Ayesha Ihsan

ORCID: 0000-0001-6605-1466
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About
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Research Areas
  • Nanoparticle-Based Drug Delivery
  • Advanced Drug Delivery Systems
  • Lipid Membrane Structure and Behavior
  • Electrochemical sensors and biosensors
  • Nanoplatforms for cancer theranostics
  • Nanocluster Synthesis and Applications
  • Bacterial biofilms and quorum sensing
  • Advanced Nanomaterials in Catalysis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Antimicrobial Peptides and Activities
  • Luminescence and Fluorescent Materials
  • Quantum Dots Synthesis And Properties
  • Copper-based nanomaterials and applications
  • Chalcogenide Semiconductor Thin Films
  • Nanoparticles: synthesis and applications
  • Antimicrobial agents and applications
  • RNA Interference and Gene Delivery
  • Electrochemical Analysis and Applications
  • Advancements in Transdermal Drug Delivery
  • Carbon and Quantum Dots Applications
  • Enzyme Catalysis and Immobilization
  • Orthopedic Infections and Treatments
  • Gas Sensing Nanomaterials and Sensors
  • Nanomaterials for catalytic reactions
  • Graphene and Nanomaterials Applications

National Institute for Biotechnology and Genetic Engineering
2015-2024

Pakistan Institute of Engineering and Applied Sciences
2020-2024

Government College University, Faisalabad
2023

Government Sadiq College Women University
2020

Abdus Salam Centre for Physics
2020

Pakistan Institute of Nuclear Science and Technology
2020

Quaid-i-Azam University
2020

University of Faisalabad
2017-2019

National Institute of Genetic Engineering and Biotechnology
2017

Czech Academy of Sciences, Institute of Biotechnology
2017

Natural antimicrobial agents, particularly essential oils present an excellent alternative to current antibiotics due their potent and broad-spectrum potential, unique mechanisms of action low tendency induce resistance. However potential as a viable therapeutic is greatly compromised hydrophobic volatile nature. The objective the research was explore anti-pathogenic in bio-based nano-carrier system. Six different were tested on multi-drug resistant bacterial pathogens. However, cardamom oil...

10.3389/fmicb.2016.01580 article EN cc-by Frontiers in Microbiology 2016-10-04

Combination therapy, especially photodynamic/photothermal therapy (PDT/PTT), has shown promising applications in cancer therapy. However, sequential irradiation by two different laser sources and even the utilization of single high-power to induce either combined PDT/PTT or individual PTT will be subjected prolonged treatment time, complicated process, potential skin burns. Thus, low power activatable is still a formidable challenge. Herein, we propose an effective strategy achieve...

10.1021/acsnano.8b09552 article EN ACS Nano 2019-02-07

Abstract: Binary fatty acid mixture-based solid lipid nanoparticles (SLNs) were prepared for delivery of diacerein, a novel disease-modifying osteoarthritis drug, with and without simultaneously loaded gold (GNPs). In order to optimize SLNs temperature-responsive release, mixtures using different ratios (stearic or lauric acid) liquid (oleic acids. by microemulsification (53 nm), hot melt encapsulation (10.4 solvent emulsification-evaporation technique (7.8 nm). The physicochemical...

10.2147/ijn.s67147 article EN cc-by-nc International Journal of Nanomedicine 2015-04-01

Frequent incidents of antibiotic-resistant biofilm forming pathogens in community-associated and hospital-acquired infections have become a global concern owing to failure conventional therapies. Nano-antibiotics (NABs) are de novo tools overcome the multi-drug resistant mechanisms employed by superbugs. Inhibition formation is one those strategies curb multi drug resistance phenomenon. In current study, anti-biofilm antibacterial potential newly synthesized cefotaxime loaded chitosan based...

10.3389/fmicb.2016.00330 article EN cc-by Frontiers in Microbiology 2016-03-18

Recently, water contamination caused by metal ions has become one of the most serious problems as it several deaths and socioeconomic around world. Hence, fast accurate detection in aqueous media important area research; from time to time, new probes have been designed for this purpose. Among previously reported sensors, based on fluorescent organic nanoparticles (FONs) gaining tremendous attention due their ease preparation/fabrication, synthetic diversity according targeted ions, quick...

10.1039/c8an01801d article EN The Analyst 2019-01-01

An electrolyte is a vital component that creates an avenue for zinc ions to migrate and forms cathode–anode intermediary in based battery system. Zinc metal thermodynamically unstable prone dissolve acidic aqueous solutions. Indeed, there are still lot of issues with using liquid on frequent basis. Given its intimate connection the ionic conductivity electrochemical stability window, liquids (ILs) deep eutectic solvents (DESs) as 'Designer electrolytes' investigated by controlling their...

10.1016/j.molliq.2021.117606 article EN cc-by-nc-nd Journal of Molecular Liquids 2021-09-20

Thermoresponsive lipid nanoparticles were formulated to transition into a liquid phase pass the blood brain barrier treat numerous disorders.

10.1039/c7nr05216b article EN Nanoscale 2017-01-01

Abstract: Thermoresponsive drug delivery systems are designed for the controlled and targeted release of therapeutic payload. These exploit hyperthermic tempera­tures (> 39°C), which may be applied by some external means or due to an encountered symptom in inflammatory diseases such as cancer arthritis. The objective this paper was provide solid evidence support hypothesis that lipid nanoparticles (SLNs) can used thermoresponsive targeting undergoing solid–liquid phase transition at their...

10.2147/ijn.s147506 article EN cc-by-nc International Journal of Nanomedicine 2017-11-01

Thyroid cancer in humans has a fast-growing prevalence, with the most common lethal endocrine malignancy for unknown reasons. The current study was aimed to perform qualitative and quantitative investigation characterization of gut bacterial composition euthyroid thyroid patients. fecal samples were collected from sixteen patients ten healthy subjects. PCR-DGGE conducted by targetting V3 region 16S rRNA gene, as well real-time PCR Bacteroides vulgatus, E.coli Bifidobacterium, Clostridium...

10.7150/jca.66816 article EN cc-by-nc Journal of Cancer 2022-01-01

Alpha-amylases hydrolyze 1,4 α-glycosidic bonds of starch and produce malto-oligosaccharides. It is an important enzyme generally applied in textile, food brewing industries. Enhancement thermal stability productivity enzymes are the two most sought after properties for industrial use. The Aspergillus oryzae (Koji) has Generally Recognized as Safe (GRAS) status safe use industry. Hence, Koji strain's development screening potent mutants, hyper producer thermostable α-amylases, with desired...

10.1186/s12866-018-1345-y article EN cc-by BMC Microbiology 2018-11-28

In the present work, novel molecularly imprinted polymer porous beads for selective separation of copper ions have been synthesized by combining two material-structuring techniques, namely, molecular imprinting and oil-in-water-in-oil emulsion polymerization. This method produces monodisperse spherical with an average diameter ∼2-3 mm, in contrast to adsorbents produced traditional way grinding sieving. Field-emission scanning electron microscopy indicates that are nature interconnected...

10.1002/jssc.201500984 article EN Journal of Separation Science 2015-12-03

Gold nanoparticles (GNPs) with dimension in the range of 1-100 nm have a prominent role number biomedical applications like imaging, drug delivery, and cancer therapy owing to their unique optical features biocompatibility. In this work, we report novel technique for synthesis two types GNPs namely porous gold (PGNPs) solid (SGNPs). PGNPs size 35 were fabricated by reduction (III) solution lecithin followed addition L-ascorbic acid tri-sodium citrate, whereas SGNPs 28 prepared reflux method...

10.2147/ijn.s127996 article EN cc-by-nc International Journal of Nanomedicine 2017-02-01
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