Ruoxuan Huang

ORCID: 0000-0001-6620-5824
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About
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Research Areas
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Corneal surgery and disorders
  • Ophthalmology and Visual Impairment Studies
  • Occupational and environmental lung diseases
  • Intraocular Surgery and Lenses
  • Extracellular vesicles in disease
  • Glaucoma and retinal disorders
  • Cancer-related molecular mechanisms research
  • Bone and Dental Protein Studies
  • CAR-T cell therapy research
  • RNA modifications and cancer
  • Inflammasome and immune disorders
  • T-cell and B-cell Immunology
  • Connective tissue disorders research
  • Immunotherapy and Immune Responses
  • Ocular Surface and Contact Lens
  • Circular RNAs in diseases
  • Mesenchymal stem cell research
  • Histiocytic Disorders and Treatments
  • Protease and Inhibitor Mechanisms

Sun Yat-sen University
2024-2025

Stomatology Hospital
2024

Zhengzhou University
2019-2021

To evaluate the predictive accuracy of 11 intraocular lens (IOL) calculation formulas in eyes with an axial length (AL) less than 22.00 mm. New-generation (Barrett Universal II [BUII], Emmetropia Verifying Optical [EVO] 2.0, Hill-Radial Basis Function [Hill-RBF] 3.0, Hoffer QST, K6, Kane, Pearl-DGS) and traditional (Haigis, Q, Holladay 1 SRK/T) were evaluated for accuracy. Subgroup analyses performed based on AL anterior chamber depth (ACD). The study enrolled a total 184 from patients....

10.1186/s12886-024-03793-z article EN cc-by-nc-nd BMC Ophthalmology 2025-01-16

Abstract Purpose To evaluate the performance of intraocular lens (IOL) calculation formulas and effect anterior chamber depth (ACD), axial length (AL) thickness (LT) on prediction accuracy in shallow ACD eyes. Methods This retrospective, consecutive case‐series study included 648 eyes patients with an < 3.0 mm who underwent phacoemulsification IOL implantation. Eleven were evaluated: Barrett Universal II (BUII), Emmetropia Verifying Optical (EVO) 2.0, Hill‐Radial Basis Function (RBF) 3.0,...

10.1111/aos.16654 article EN Acta Ophthalmologica 2024-02-09

This study aimed to investigate the effect of bone marrow-derived mesenchymal stem cells (BMSCs) on silica-induced lung fibrosis in a rat model. Thirty SD rats were randomly divided into three groups: control group, silica and BMSC group (n = 10 per group). BMSCs injected successively 14th, 28th, 42nd days after exposure. All sacrificed 56 We detected pathological fibrotic changes, apoptosis, autophagy, pyroptosis their tissue by histopathological examination, hydroxyproline content assays,...

10.1016/j.ecoenv.2021.112181 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-04-10

Abstract Silicosis is a devastating occupational disease caused by long‐term inhalation of silica particles, inducing irreversible lung damage and affecting function, without effective treatment. Mesenchymal stem cells (MSCs) are heterogeneous subset adult that exhibit excellent self‐renewal capacity, multi‐lineage differentiation potential immunomodulatory properties. The aim this study was to explore the effect bone marrow‐derived mesenchymal (BMSCs) in silica‐induced rat model pulmonary...

10.1111/jcmm.16621 article EN cc-by Journal of Cellular and Molecular Medicine 2021-06-02

Purpose: To investigate the impact of back-to-front corneal radius ratio (B/F ratio) and posterior keratometry (PK) on accuracy intraocular lens power calculation formulas in eyes after myopic laser situ keratomileusis (LASIK)/photorefractive keratectomy (PRK) surgery. Methods: A retrospective, consecutive case series study included 101 patients (132 eyes) with cataract LASIK/PRK. Mean prediction error (PE), mean absolute PE (MAE), median (MedAE), percentage within ±0.25, ±0.50, ±1.00...

10.3928/1081597x-20240718-01 article EN Journal of Refractive Surgery 2024-09-01

Esophageal cancer is one of the most deadly malignant tumors. Among common tumors in world, esophageal ranked seventh, which has a high mortality rate. Long noncoding RNAs (lncRNAs) play an important role occurrence and development various lncRNAs can competitively bind microRNAs (miRNAs) with mRNA, regulate expression level encoded gene at posttranscriptional level. This regulatory mechanism called competitive endogenous RNA (ceRNA) hypothesis, ceRNA research value tumor-related research....

10.1155/2020/3075729 article EN cc-by BioMed Research International 2020-12-10

<title>Abstract</title> A fundamental question in oral science is elucidating the factors that underpin distinct tissue characteristics of human keratinized and non-keratinized mucosa. Clinical autotransplantation large animal studies have observed intrinsic regulation within connective defines mucosal phenotypes, emphasizing need for in-depth molecular characterization, which remains largely unexplored. This study aimed to map blueprints <italic>in situ</italic> tissues isolated fibroblasts...

10.21203/rs.3.rs-5368489/v1 preprint EN cc-by Research Square (Research Square) 2024-11-14

To investigate the proportion of patients with predicted refractive astigmatism (PRA) 0.75 diopters (D) or greater and associated risk factors among cataract surgery candidates low corneal astigmatism.A retrospective cross-sectional study was conducted in Zhongshan Ophthalmic Center, Guangzhou, China. Patients who had preoperative simulated keratometric less than D were recruited. The PRA calculated by Barrett toric calculator using posterior (PCA) measured IOLMaster 700 (Carl Zeiss Meditec...

10.3928/1081597x-20231106-03 article EN Journal of Refractive Surgery 2023-12-01
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