Leyao Xu

ORCID: 0000-0002-1684-8335
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About
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Research Areas
  • Advanced Photocatalysis Techniques
  • Aluminum Alloys Composites Properties
  • MXene and MAX Phase Materials
  • Bone Tissue Engineering Materials
  • Advanced ceramic materials synthesis
  • Bone and Dental Protein Studies
  • Microstructure and mechanical properties
  • Electromagnetic wave absorption materials
  • Transition Metal Oxide Nanomaterials
  • Covalent Organic Framework Applications
  • 2D Materials and Applications
  • Mechanical Behavior of Composites
  • Bone Metabolism and Diseases
  • Connective tissue disorders research
  • Nanoporous metals and alloys
  • Anodic Oxide Films and Nanostructures
  • Copper Interconnects and Reliability
  • nanoparticles nucleation surface interactions
  • Advanced Materials Characterization Techniques
  • Injection Molding Process and Properties
  • Surface Modification and Superhydrophobicity
  • Advanced materials and composites
  • Perovskite Materials and Applications
  • Metabolism, Diabetes, and Cancer
  • Protease and Inhibitor Mechanisms

Sun Yat-sen University
2022-2025

Stomatology Hospital
2022-2025

Hospital of Stomatology, Sun Yat-sen University
2022-2024

Northwest University
2022-2024

Shandong University of Science and Technology
2023-2024

Ningbo University of Technology
2021-2023

We reported the rationally designed Ta 3 N 5 @ReS 2 heterojunctions with promoted photocatalytic hydrogen evolution, which is ∼16 times higher than that of counterpart, and superior to those -based photocatalysts ever reported.

10.1039/d1ta09030e article EN Journal of Materials Chemistry A 2021-01-01

Biological-derived hydroxyapatite is widely used as a bone substitute for addressing defects, but its limited osteoconductive properties necessitate further improvement. The osteo-immunomodulatory hold crucial promise in maintaining homeostasis, and precise modulation of macrophage polarization essential this process. Metabolism serves guiding force immunity, fluoride modification represents promising strategy modulating the osteoimmunological environment by regulating immunometabolism. In...

10.1186/s12967-024-05261-0 article EN cc-by Journal of Translational Medicine 2024-05-08

Biological hydroxyapatite (BHA) has been extensively employed in alveolar socket preservation, yet its clinical application is often compromised by delayed bone healing triggered macrophage-mediated pro-inflammatory responses. Building upon our previous work, which we successfully incorporated fluorine into BHA to develop fluorinated biogenic (FBHA) with superior physicochemical and biological properties, this study systematically investigated the effects of doping on osteoimmunomodulation...

10.3390/bioengineering12040396 article EN cc-by Bioengineering 2025-04-07

Two-dimensional germanium is considered a promising new channel material to replace silicon owing its lower effective mass and larger electron–hole mobility. To investigate the transport characteristics of single-layer germanane transistors with gate lengths (Lg) below 5 nm, we utilize an ab initio quantum methodology. It was found that n-type having Lg 3 nm satisfy International Technology Roadmap for Semiconductors (ITRS) requirements on-state current (Ion), delay time, power-delay...

10.1063/5.0192389 article EN cc-by-nc-nd Journal of Applied Physics 2024-04-05

<title>Abstract</title> A fundamental question in oral science is elucidating the factors that underpin distinct tissue characteristics of human keratinized and non-keratinized mucosa. Clinical autotransplantation large animal studies have observed intrinsic regulation within connective defines mucosal phenotypes, emphasizing need for in-depth molecular characterization, which remains largely unexplored. This study aimed to map blueprints <italic>in situ</italic> tissues isolated fibroblasts...

10.21203/rs.3.rs-5368489/v1 preprint EN cc-by Research Square (Research Square) 2024-11-14

2-deoxyglucose (2-DG), targeting Hexokinase I (HKI) to inhibit glycolysis in cancer cells, has inspired drug design. Increasing evidence suggests that its phosphorylated form, 2-deoxyglucose-6-phosphate (2-DG-6-P), may HKI more effectively, highlighting the need understand molecular mechanisms behind this effect. Using simulations, we examined interactions between and substrates—glucose (G) glucose-6-phosphate (G-6-P)—and inhibitors—2-DG 2-DG-6-P. G G-6-P showed stable with HKI, involving...

10.20944/preprints202411.2341.v1 preprint EN 2024-11-29
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