A5070674964- Transportation Planning and Optimization
- Bacteriophages and microbial interactions
- Bacterial Genetics and Biotechnology
- Urban Transport and Accessibility
- Antibiotic Resistance in Bacteria
- Transportation and Mobility Innovations
- Urban Design and Spatial Analysis
- Clostridium difficile and Clostridium perfringens research
- Evaluation and Optimization Models
- Legionella and Acanthamoeba research
- Gut microbiota and health
- Legume Nitrogen Fixing Symbiosis
- Enterobacteriaceae and Cronobacter Research
- Multi-Criteria Decision Making
- Genomics and Phylogenetic Studies
- Complex Network Analysis Techniques
- Biosensors and Analytical Detection
- Economic and Environmental Valuation
- Early Childhood Education and Development
- Antimicrobial Peptides and Activities
- Probiotics and Fermented Foods
- Listeria monocytogenes in Food Safety
- Vibrio bacteria research studies
- Pharmacological Effects of Natural Compounds
- Microbial infections and disease research
Kyungpook National University
2020-2024
Ajou University
2013-2018
Yonsei University
2007
Multidrug-resistant (MDR) bacteria are a major threat to public health. Bacteriophage endolysins (lysins) promising alternative treatment traditional antibiotics. However, the lysins currently under development still underestimated. Herein, we cloned lysin from SAP-26 bacteriophage genome. The recombinant LysSAP26 protein inhibited growth of carbapenem-resistant Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa, oxacillin-resistant Staphylococcus...
This research developed a geographical presentation method to show which areas of the city need be improved in terms directness transit service using two measures, Degree Competitiveness and Circuity, were first author's previous research. In this research, networks five cities Korea was analyzed compared as an example demonstrated geographically. The results that although more populated are likely provide direct than less cities, population density affects network more. Also, showed there...
Nosocomial infections caused by multidrug-resistant (MDR) bacteria are severe life-threatening factors. Endolysins (lysins) degrade the bacterial cell wall peptidoglycan and may help control pathogens, especially MDR prevalent in hospital settings. This study was conducted to verify potential of lysin as disinfectant kill contaminating medical devices that cause infections. Eight catheters removed from hospitalized patients were collected tested for their ability using two lysins, LysSS...
Abstract Background Development of novel antimicrobial agents is imperative due to the increasing threat antibiotic-resistant pathogens. This study aimed validate enhanced antibacterial activity and in vivo efficacy a truncated endolysin, CHAP SAP26 -161, derived from domain LysSAP26, against multidrug-resistant bacteria. Methods Two deletion mutants, -139 were constructed by deleting C-terminal portion LysSAP26. These cloned expressed, their activities, together with protein purification...
In this study, value of VMS (Variable Message Sign) traffic information is estimated by using CVM (Contingent Valuation Method), which developed to quantify the non-marketable goods in environmental economics. used estimate provided a project under consideration and then feasibility can be indirectly examined on basis value. This study focuses estimating through VMS, part transportation system enhancement Korea Expressway Corporation aimed at mitigating problems expressways. particular,...
Clostridioides difficile is a spore-forming enteric pathogen that causes life-threatening diarrhea and colitis. Notably, C. infection (CDI) major healthcare-associated with increasing incidence morbidity rates. Antibiotic-induced microbial disruption has been linked to susceptibility CDI transmission relapse. Therefore, alternative therapeutic approaches effectively prevent growth spore germination are urgently needed. Bacteriophage-derived endolysins their derivatives have recently shown...
Personal Rapid Transit(PRT)는 대중교통중심의 지속가능한 사회를 위한 교통수단으로 각광받고 있다. 본 연구에서는 경험하지 못한 교통수단에 대한 이용자들의 인식을 효과적으로 측정하기 설문 설계방법을 제시하고, PRT 잠재적 지불의사액(WTP: Willingness-to-pay)을 고려한 수단전환율 모형을 구축하여 이용경험이 부재한 사람들의 교통수단 이용선호의 변화를 분석하였다. 또한, 연구의 적정성을 검증하기 위해 설문조사 결과를 기초로 구축된 추정모형을 도입이 논의 중인 송도신도시에 적용하여 이용수요를 예측하고, 요금수준에 따른 수단전환율의 기존 예측모형의 결과와 비교하였다. 모형적용결과를 통해 연구에서 제안된 설계방식은 이용선호와 관련된 설명변수를 측정함을 알 수 예측에 있어서, 제시하고 있는 모형이 모형보다 이용자가 느끼는 요금에 저항을 현실적으로 반영하는 것으로 나타났다. Transit(PRT) has emerged as a promising...