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A5116713519Rutgers, The State University of New Jersey
2025
Abstract Dysregulated innate immune responses contribute to multisystem inflammatory syndrome in children (MIS-C), characterized by gastrointestinal, mucocutaneous, and/or cardiovascular injury occurring weeks after severe acute respiratory coronavirus 2 (SARS-CoV-2) exposure. To investigate functions, we stimulated ex vivo peripheral blood cells from MIS-C patients with agonists of Toll-like receptors (TLR), key response initiators. We found severely dampened cytokine and elevated gene...
10.1093/jimmun/vkaf006
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The Journal of Immunology
2025-03-18
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