Alexander Vakurov

ORCID: 0000-0001-6654-4287
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About
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Research Areas
  • Electrochemical sensors and biosensors
  • Electrochemical Analysis and Applications
  • Lipid Membrane Structure and Behavior
  • Enzyme Catalysis and Immobilization
  • Luminescence Properties of Advanced Materials
  • Advanced biosensing and bioanalysis techniques
  • Analytical Chemistry and Sensors
  • Nanoparticles: synthesis and applications
  • bioluminescence and chemiluminescence research
  • Analytical Chemistry and Chromatography
  • Biotin and Related Studies
  • Radiation Detection and Scintillator Technologies
  • Advanced Photocatalysis Techniques
  • Molecular Junctions and Nanostructures
  • Chemical Synthesis and Analysis
  • Mass Spectrometry Techniques and Applications
  • Enzyme-mediated dye degradation
  • Nanoparticle-Based Drug Delivery
  • Force Microscopy Techniques and Applications
  • Spectroscopy and Quantum Chemical Studies
  • Nuclear materials and radiation effects
  • Hydrogels: synthesis, properties, applications
  • Analytical chemistry methods development
  • Advanced Polymer Synthesis and Characterization
  • Cholinesterase and Neurodegenerative Diseases

University of Leeds
2010-2022

University of Engineering and Technology Lahore
2017

Aarhus University
2017

Lomonosov Moscow State University
1994-2000

In this study, the effect of ZnO nanoparticles and ZnCl2 on growth, reproduction accumulation zinc in Daphnia magna was determined a 21-day chronic toxicity test. A variety techniques were used to distinguish free ion, dissolved, nanoparticle aggregated fraction test medium. The results showed similar effects for (EC10, 20, 50 reproduction: 0.030, 0.049, 0.112 mg Zn/l) 0.014, 0.027, 0.082 Zn/l). large rapidly dissolved after introduction exposure Aggregation also observed but within 48 h...

10.3109/17435390.2013.822594 article EN Nanotoxicology 2013-07-10

Upconversion nanoparticles (UCNPs) are utilized extensively for biomedical imaging, sensing, and therapeutic applications, yet the molecular weight of UCNPs has not previously been reported. Herein, we present a theory based upon crystal structure to estimate UCNPs: enabling insight into UCNP first time. We theoretical various reported in literature, predicting that spherical NaYF4 ~ 10 nm diameter will be ~1 MDa (i.e.

10.1038/s41598-018-19415-w article EN cc-by Scientific Reports 2018-01-12

Formation of noncovalent complexes between α-chymotrypsin (CT) and a polyelectrolyte, polybrene (PB), has been shown to produce two major effects on enzymatic reactions in binary mixtures polar organic cosolvents with water. (i) At moderate concentrations (10% 30% v/v), activity CT is higher than aqueous solutions, this activation effect more significant for complex PB (5- 7-fold) free enzyme (1.5- 2.5-fold). (ii) The range cosolvent that the tolerates without complete loss catalytic much...

10.1002/(sici)1097-0290(19970720)55:2<267::aid-bit4>3.0.co;2-g article EN Biotechnology and Bioengineering 1997-07-20

The interaction of amorphous colloidal silica (SiO2) nanoparticles well-defined sizes with a dioleoyl phosphatidylcholine (DOPC) monolayer on mercury (Hg) film electrode has been investigated. It was shown using electrochemical methods and microcalorimetry that particles interact the monolayer, data shows extent is inversely proportional to particle size. Scanning electron microscopy (SEM) images electrode-supported monolayers following exposure bind DOPC irrespective their size, forming...

10.1021/la203568n article EN Langmuir 2011-12-05

Upconversion nanoparticles (UCNPs) with sodium yttrium fluoride, NaYF

10.1002/jbio.201800256 article EN cc-by Journal of Biophotonics 2018-10-23

To test the biocompatible character of room-temperature ionic liquids (ILs), interaction various ILs with biological membrane (biomembrane) models was studied in this work. Dioleoyl phosphatidylcholine (DOPC) adsorbed on a mercury (Hg) electrode forms an impermeable defect-free monolayer which is well established biomembrane model, prone to be by electrochemical techniques. We have monitored modifications Hg supported caused using rapid cyclic voltammetry (RCV), alternating current (ACV),...

10.1021/la400923d article EN Langmuir 2013-05-08

Phospholipid monolayers on mercury (Hg) surfaces have received substantial and extensive scientific interest not only because of their use as a biomembrane model but also for application successful toxicity-sensing element. The show characteristic very reproducible phase transitions manifest consecutive voltammetric peaks in response to applied transverse electric fields. Unfortunately, apart from the results simulation studies, there is lack data lipid structures help interpret these peaks....

10.1021/nn4037267 article EN ACS Nano 2014-03-13

Aims: Neuropeptide substance P (SP) is produced and released by a subset of peripheral sensory neurons that respond to tissue damage (nociceptors). SP exerts excitatory effects in the central nervous system, but actions are still poorly understood; therefore, here, we aimed at investigating these mechanisms. Results: acutely inhibited T-type voltage-gated Ca2+ channels nociceptors. The effect was mediated neurokinin 1 (NK1) receptor-induced stimulation intracellular release reactive oxygen...

10.1089/ars.2015.6560 article EN cc-by Antioxidants and Redox Signaling 2016-06-16

Up-conversion nanoparticles (UCNPs) of sodium yttrium fluoride with ytterbium and erbium ions as sensitizer activator (β-NaYF4/Yb3+/Er3+) have been synthesised by a solvothermal method. The particles were found to be highly uniform in size (~50 nm) hexagonal crystal phase producing strong up-conversion luminescence dominated the green wavelength region. During synthesis, photoluminescence properties reaction mixture monitored at regular intervals ensure required particle distribution...

10.1016/j.bioadv.2022.212763 article EN cc-by Biomaterials Advances 2022-03-17

Dual labeled contrast agents could provide better complementary information for bioimaging than available solely from a single modality. In this paper we investigate the suitability of Yb3+ and Er3+-doped BaYF5 upconversion nanoparticles (UCNPs) as both optical X-ray micro computed tomography (μCT) agents. Stable, aqueous UCNP dispersions were synthesised using hydrothermal method with addition polyethyleneimine (PEI). UCNPs crystal had truncated cuboidal and/or octahedral morphology,...

10.1016/j.msec.2021.111937 article EN cc-by Materials Science and Engineering C 2021-02-06
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