A5011485071- RNA Research and Splicing
- Obstructive Sleep Apnea Research
- Spondyloarthritis Studies and Treatments
- Sleep and Work-Related Fatigue
- Lipid metabolism and disorders
- Cancer, Lipids, and Metabolism
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- RNA modifications and cancer
- Neuroscience of respiration and sleep
- Lipoproteins and Cardiovascular Health
- Rheumatoid Arthritis Research and Therapies
- Cytokine Signaling Pathways and Interactions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Spine and Intervertebral Disc Pathology
- Growth Hormone and Insulin-like Growth Factors
- Osteomyelitis and Bone Disorders Research
- Urban Transport and Accessibility
- Musculoskeletal pain and rehabilitation
- Retinoids in leukemia and cellular processes
- Liver Disease Diagnosis and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Skin and Cellular Biology Research
- Hearing, Cochlea, Tinnitus, Genetics
- Wnt/β-catenin signaling in development and cancer
- Cardiovascular and Diving-Related Complications
Changhua Christian Hospital
2021-2025
Harvard University
2021
Tri-Service General Hospital
2020
National Defense Medical Center
2019-2020
Ichthyosis are complex skin diseases, characterized by hyperkeratosis with various degrees of thickening, desquamation, and erythema. The prenatal diagnosis ichthyosis is challenged due to the clinical genetic heterogeneity late-onset fetal features on ultrasound scan. Here, we reported two fetuses Harlequin (HI), a severe subtype autosomal recessive congenital (ARCI), who were diagnosed prenatally images investigations. Preimplantation testing (PGT) was also performed in one case family...
Statins inhibiting 3-hydroxy-3-methylglutaryl-CoA reductase are the standard treatment for hypercholesterolemia in atherosclerotic cardiovascular disease (ASCVD), mediated by inflammatory reactions within vessel walls. Several studies highlighted pleiotropic effects of statins beyond their lipid-lowering properties. However, few investigated on T cell activation. This study evaluated immunomodulatory capacities three common statins, pitavastatin, atorvastatin, and rosuvastatin, activated...
To determine the risk of having OSA in a cohort female subjects who are infertile and odds being women with OSA.
Posttranscriptional gene regulation by Adenylate Uridylate (AU) rich element RNA binding protein, Elavl1 has been implicated in embryonic development as well progenitor cell differentiation. binds to hundreds of cellular messenger RNAs predominantly through interactions with AU-rich elements (AREs) found the untranslated regions (UTRs) and functions regulating their stability. Biological during osteogenic differentiation bone marrow derived mesenchymal stem cells is not well-understood. Here...
Abstract Hearing loss becomes increasingly common with age and affects quality of life. Recently, scientists have published articles about the relationship between metabolic disease hearing loss. Metabolic was previously found to be highly related an increase in alkaline phosphatase. Thus, there may indirect phosphatase (ALP) In this paper, we will demonstrate ALP We included 3877 National Health Nutrition Examination Survey (NHANES) participants, who represent noninstitutionalized civilian...
Abstract Non-apnea sleep disorder (NASD) increases the risk of motor vehicle accidents. However, systemic review NASD and its for all causes injury is lacking. The aim present study was to provide a detailed demographic data on in 14-year follow up. Our utilized outpatient inpatient from Longitudinal Health Insurance Database between 2000 2013 Taiwan. We enrolled 989,753 individuals aged ≥20 years who were diagnosed with as outpatients ≥3 times or inpatients ≥1 time. matched cohort...
Background: Human epididymis protein 4 (HE4) has been frequently used to study in many malignant tumors, while serum nutritional markers are determine a person’s health status. However, the link between micronutrient concentrations and HE4 not yet clarified. Methods: A total of 2464 eligible female participants biomarkers were chosen from National Health Nutrition Examination Surveys (NHANES) 2001– 2002. For statistical analysis, we χ 2 test, multivariable linear regression, analysis...
Introduction: An important clinical feature of metabolic syndrome is abdominal obesity. Microalbuminuria in predicting the risk cardiovascular and renal complications obesity patients. However, association between microalbuminuria polymorphism has not been conducted. The objective this study to analyze genetic participants with metabolically unhealthy (MUO). Methods: Among 1325 MUO participants, we identified genomic loci underlying those microalbuminuria, compared without microalbuminuria....