A5055788193- Plant-Microbe Interactions and Immunity
- Immune Response and Inflammation
- Plant Molecular Biology Research
- Plant Pathogenic Bacteria Studies
- Antimicrobial Peptides and Activities
- Microbial Natural Products and Biosynthesis
- Polysaccharides and Plant Cell Walls
- Natural product bioactivities and synthesis
- Plant Pathogens and Fungal Diseases
- Invertebrate Immune Response Mechanisms
University of Zurich
2021-2024
Max Planck Institute for Plant Breeding Research
2021-2022
Toll/Interleukin-1 receptor (TIR) domains are integral to immune systems across all kingdoms. In plants, TIRs present in nucleotide-binding leucine-rich repeat (NLR) receptors, NLR-like, and TIR-only proteins. Although TIR-NLR TIR signaling plants require the ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1) protein family, persist species that have no EDS1 members. To assess whether particular groups evolved with EDS1, we searched for TIR-EDS1 co-occurrence patterns. Using a large-scale phylogenetic...
Abstract Toll/interleukin-1 Receptor (TIR) domains are integral to immune systems across all of life. TIRs exist as single-domain and larger receptor or adaptor proteins. In plants, constitute N-terminal nucleotide-binding leucine-rich repeat (NLR) receptors. Although TIR-NLR TIR signaling requires the Enhanced disease susceptibility 1 (EDS1) protein family, persist in species that have incomplete no EDS1 members. To assess whether particular groups appear with EDS1, we searched for TIR-EDS1...
ABSTRACT Ligand recognition by cell-surface receptors underlies development and immunity in both animals plants. Modulating receptor signaling is critical for appropriate cellular responses but the mechanisms ensuring this are poorly understood. Here, we show that plant pathogen-associated molecular patterns (PAMPs) CLAVATA3/EMBRYO SURROUNDING REGION-RELATED peptides (CLEp) employ a similar regulatory module. In absence of ligand, dampened through association with specific type-2C protein...