- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Breast Implant and Reconstruction
- Cancer Diagnosis and Treatment
- Historical Studies and Socio-cultural Analysis
- French Urban and Social Studies
- Ear and Head Tumors
- Pituitary Gland Disorders and Treatments
- European Political History Analysis
- Bone fractures and treatments
- Cancer Immunotherapy and Biomarkers
- Adrenal and Paraganglionic Tumors
- Salivary Gland Tumors Diagnosis and Treatment
- Meningioma and schwannoma management
- Trauma Management and Diagnosis
- Sinusitis and nasal conditions
- Tracheal and airway disorders
- Nonmelanoma Skin Cancer Studies
- Pancreatic and Hepatic Oncology Research
- French Historical and Cultural Studies
- Mesenchymal stem cell research
- Orthopedic Surgery and Rehabilitation
- Glioma Diagnosis and Treatment
Bordeaux Population Health
2021-2025
Inserm
2021-2025
Louisiana State University Health Sciences Center New Orleans
2013-2025
Université de Bordeaux
2018-2025
Hôpital Cardiologique du Haut-Lévêque
2015-2024
Centre Hospitalier Universitaire de Bordeaux
2015-2024
Université de Rouen Normandie
2024
Centre Henri Becquerel
2024
University Medical Center New Orleans
1997-2021
Centre Antoine Lacassagne
2019
This study examined 758 deep inferior epigastric perforator flaps for breast reconstruction, with respect to risk factors and associated complications. Risk that demonstrated significant association any or abdominal complication included smoking (p = 0.0000), postreconstruction radiotherapy hypertension 0.0370). Ninety-eight (12.9 percent) developed fat necrosis. Associated were 0.0226) 0.0000). Interestingly, as the number of perforators increased, so did incidence There only 19 cases (2.5...
Tissue resident mesenchymal stem cells (MSCs) are known to participate in tissue regeneration that follows cell turnover, apoptosis, or necrosis. It has been long aging impedes an organism's repair/regeneration capabilities. In order study the age associated changes, molecular characteristics of adipose derived MSCs (ASCs) from three groups healthy volunteers i.e., young, middle aged, and aged were investigated. The number multilineage differentiation potential ASCs declined with age. Aging...
Due to its increasing popularity, more and articles on the use of perforator flaps have been reported in literature during past few years. Because area is new rapidly evolving, there are no definitions standard rules terminology nomenclature, which creates confusion when surgeons try communicate compare surgical techniques. This article attempts represent opinion a group pioneers field flap surgery. consensus was reached after meeting held Fifth International Course Perforator Flaps Gent,...
Type 2 diabetes is associated with numerous long-term complications. This study aims to investigate whether impaired function of tissue-resident multipotent cells play role in pathogenesis allied Adipose-tissue-derived mesenchymal stem (ASCs) derived from nondiabetic (nASCs) and diabetic (dASCs) donors were compared regard glucose metabolism, cell replication, apoptosis, differentiation potential. The data evidenced that elevation reduces proliferative capacity both dASCs nASCs, but impacts...
The most common recipient site for free-flap breast reconstruction is the subscapular system. Because of a number problems we encountered using this site, became interested in revisiting internal mammary vessels. This paper reports use artery and vein as 110 consecutive cases 87 patients. We also report technical details recipient-vessel dissection vessel size our series. Complications series are discussed, advantages vessels enumerated. Our experience 99 percent successful flap transfer...
Bilateral prophylactic mastectomy can reduce the incidence of breast cancer by 87 to 93% in high-risk individuals and is an appealing option for many patients if reconstruction be provided with acceptable morbidity outstanding esthetic results. Autogenous techniques have evolved over last 20 years meet this goal. Familiarity deep inferior epigastric perforator (DIEP) flap led us carry out simultaneous bilateral superior outcome 3 patient groups: (1) after mastectomy, (2) therapeutic...
Fujino was the first to introduce gluteal tissue as a free flap for breast reconstruction. The use of musculocutaneous from buttock in reconstruction has been championed by Shaw. Despite initial enthusiasm this area donor site, few other large series exist on subject. Two decades experience with region site led recognition advantages and drawbacks. Furthermore, both superior inferior associated certain important complications vein grafts allow microvascular anastomosis. evolution transfer...
The thoracodorsal artery perforator flap is a relatively new that has yet to find its niche in reconstructive surgery. At the authors' institution it been used for limb salvage, head and neck reconstruction, trunk reconstruction cases related trauma, burns, malignancy. authors have found be advantageous cranial base resurfacing face oral cavity. successfully of traumatic upper lower extremity defects, can as pedicled or free tissue transfer. perforating branches offer robust blood supply...
Complex osteocutaneous maxillofacial reconstruction requiring multiple free flaps and with an extensive zone of injury can be fraught complications difficulty. Often, the remnants native mandible are malpositioned skeletal structure upper face is distorted. The authors seek to extend use virtual planning complex by presenting their early experience in these difficult patients.A retrospective chart review 10 consecutive patients who underwent using surgical was undertaken. define as that flap...
Breast cancer is primarily a diagnosis of older women. Many patients seeking breast reconstruction are elderly women (aged 65 years or older). However, many surgeons anecdotally believe that surgery in inherently dangerous, at least prone to more complications.The authors conducted retrospective cohort study composed chart review all deep inferior epigastric perforator flap single institution divided into an (65 older) and nonelderly (younger than years). Cohort was the primary predictor...
Nasal reconstruction is a constantly evolving area of plastic surgery. Many nasal defects are managed with staged local or regional flaps, which often impart significant donor site morbidity and may place psychosocial stress on patients. Full-thickness skin grafts (FTSGs) viable option for reconstruction. When FTSGs used, the typically taken from behind in front ear, though this does not always match well. This study examines use forehead, specifically widow's peak area, to reconstruct...
White adipose tissue (WAT) is a critical organ in both health and disease. However, physiologically faithful culture models of primary human WAT remain limited, at best. In this study we describe novel system which sandwiched between tissue-engineered sheets adipose-derived stromal cells. This construct, called "sandwiched white tissue" (SWAT), can be defined as microphysiological (MPS) since it tissue-engineered, multicellular, three-dimensional construct produced using We validated SWAT...
Natural history and optimal therapeutic strategies of patients with head-and-neck paragangliomas (HNPGL) associated germline mutations in succinate dehydrogenase genes (SDHx) are barely known. This study aims to describe the outcome these depending on selected strategies. We retrospectively analyzed 65 SDHx-mutated presenting 108 HNPGL mostly located carotid (57%) jugulotympanic (JT) (21.5%) areas. One hundred five HNPGLs (97%) were nonsecreting nonmetastatic, multiple tumors observed 40...