A5026832269- Asthma and respiratory diseases
- Air Quality and Health Impacts
- Noise Effects and Management
- Indoor Air Quality and Microbial Exposure
- Allergic Rhinitis and Sensitization
- Pediatric health and respiratory diseases
- Neonatal Respiratory Health Research
- Urban Green Space and Health
- Health and Medical Studies
- Dermatology and Skin Diseases
- Respiratory viral infections research
- Climate Change and Health Impacts
- Child and Adolescent Health
- Health Literacy and Information Accessibility
- Misinformation and Its Impacts
- Health, Environment, Cognitive Aging
- Workplace Health and Well-being
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inhalation and Respiratory Drug Delivery
- Contact Dermatitis and Allergies
- Health disparities and outcomes
- Behavioral Health and Interventions
- Vaccine Coverage and Hesitancy
- Congenital Diaphragmatic Hernia Studies
- Food Allergy and Anaphylaxis Research
Finnish Institute for Health and Welfare
2022-2024
University of Würzburg
2021-2023
Otto-von-Guericke University Magdeburg
2020-2021
University of Regensburg
2019
Universitat Pompeu Fabra
2016-2018
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2016-2018
Barcelona Institute for Global Health
2016-2018
Center for Research in Environmental Epidemiology
2016-2017
Municipal Institute for Medical Research
2017
Helmholtz Zentrum München
2010-2016
Although epidemiological studies suggest that exposure to maternal smoking during fetal and early life increases the risk of childhood wheezing asthma, previous were not able differentiate effects prenatal from postnatal exposure.To assess effect only pregnancy on wheeze asthma among preschool-age children.A pooled analysis was performed based individual participant data eight European birth cohorts. Cohort-specific pregnancy, but first year, at 4 6 years age estimated using logistic...
The aim of this study was to determine the effect six traffic-related air pollution metrics (nitrogen dioxide, nitrogen oxides, particulate matter with an aerodynamic diameter <10 μm (PM 10 ), PM 2.5 , coarse and absorbance) on childhood asthma wheeze prevalence in five European birth cohorts: MAAS (England, UK), BAMSE (Sweden), PIAMA (the Netherlands), GINI LISA (both Germany, divided into north south areas). Land-use regression models were developed for each area used estimate outdoor...
We assessed the effect of three different indices urban built environment on allergic and respiratory conditions.This study involved 2472 children participating in ongoing INMA birth cohort located two bio-geographic regions (Euro-Siberian Mediterranean) Spain. Residential surrounding was characterised as 1) residential greenness based satellite-derived normalised difference vegetation index (NDVI), 2) proximity to green spaces 3) greyness land use patterns. Information wheezing, bronchitis,...
Background: Natural environments, including green spaces, may have beneficial impacts on brain development. However, longitudinal evidence of an association between long-term exposure to spaces and cognitive development (including attention) in children is limited. Objectives: We evaluated the lifelong residential space attention during preschool early primary school years. Methods: This study was based data from two well-established population-based birth cohorts Spain. assessed surrounding...
People spend most of their time inside buildings and the indoor microbiome is a major part our everyday environment. It affects humans' wellbeing therefore its composition important for use in inferring human health impacts. still not well understood how environmental conditions affect microbial communities. Existing studies have mostly focussed on local (e.g., building units) or continental scale rarely regional scale, e.g. specific metropolitan area. Therefore, we wanted to identify key...
Asthma, rhinitis and eczema often co-occur in children, but their interrelationships at the population level have been poorly addressed. We assessed co-occurrence of childhood asthma, using unsupervised statistical techniques.We included 17 209 children 4 years 14 585 8 from seven European population-based birth cohorts (MeDALL project). At each age period, were grouped, partitioning cluster analysis, according to distribution 23 variables covering symptoms 'ever' 'in last 12 months', doctor...
We studied dampness and mold in homes relation to climate, building characteristics socio-economic status (SES) across Europe, for 7127 22 centers. A subsample of 3118 was inspected. Multilevel analysis applied, including age, gender, center, SES, factors. Self-reported water damage (10%), damp spots (21%), (16%) past year were similar as observed data (19% 14% mold). Ambient temperature associated with self-reported (OR=1.63 per 10°C; 95% CI 1.02-2.63), (OR=2.95; 1.98-4.39), (OR=2.28;...
For a long time, exposure to mould and dampness-derived microbial components was considered risk factor for the development of respiratory diseases symptoms. Some recent studies suggested that early childhood components, such as (1,3)-β-d-glucan extracellular polysaccharides (EPSs), may protect children from developing allergy. We investigated association (1,3)-β-d-glucan, EPS endotoxin with asthma allergies in 6-yr-old children. This investigation follow-up nested case–control study among...
Investigations in urban areas have just begun to explore how the indoor dust microbiome may affect pathogenesis of asthma and allery.We aimed investigate early fungal bacterial house with allergic sensitization wheezing later childhood.Individual samples from 189 homes LISAplus birth cohort study were collected shortly after living room floors profiled for microbiome. Fungal diversity was assessed terminal restriction fragment length polymorphism (tRFLP) defined by Simpson's Diversity Index....
The relation between IgE sensitization and allergic respiratory symptoms has usually been evaluated by dichotomizing specific levels. aim of this study was to evaluate the association levels risk on allergen-related exposure, with special reference asthma-rhinitis comorbidity.We considered 6391 subjects enrolled within European Community Respiratory Health Survey 2, having information cat/grass/D. pteronyssinus exposure animals/pollen/dust. oculonasal/asthmalike/both a multinomial logistic...
Exposure to indoor allergens during early life may play a role in the development of immune system and inception asthma.To describe house dust mite (HDM) allergen concentrations bedroom evaluate its associations with HDM sensitization, wheezing, asthma, from birth school age, 5 geographically spread European cohorts.We included 4334 children INMA-Menorca (Spain), BAMSE (Sweden), LISAplus MAS (Germany), PIAMA-NHS (the Netherlands). Dust samples were collected bedrooms analyzed for...
Exposure to mould or dampness at home has been associated with adverse respiratory effects in all age groups. This exposure also related insomnia adults. We aimed investigate the association between visible and sleep problems children.The study population consisted of 1719 10-year-old children from German population-based birth cohort LISAplus available data on current problems. The presence was assessed by questionnaire. Parent-reported their child were analysed four binary variables: any...
<b><i>Background:</i></b> Numerous birth cohorts have been initiated in the world over past 30 years using heterogeneous methods to assess incidence, course and risk factors of asthma allergies. The aim present work is provide stepwise proceedings development current version harmonized MeDALL-Core Questionnaire (MeDALL-CQ) used prospectively 11 European cohorts. <b><i>Methods:</i></b> harmonization questions was accomplished 4 steps: (i)...
Dampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to assess predictors of microbial mattress dust throughout Europe investigate associations between exposures, home characteristics Seven different fungal bacterial parameters were assessed from 956 ECRHS II participants addition interview based characteristics. Associations asthma score lung...