A5022320937- Cardiac Imaging and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Acute Myocardial Infarction Research
- Advanced MRI Techniques and Applications
- Medical Imaging Techniques and Applications
- Lung Cancer Treatments and Mutations
- Cardiac Health and Mental Health
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Congenital Heart Disease Studies
- Occupational exposure and asthma
- Health Promotion and Cardiovascular Prevention
- Occupational and environmental lung diseases
- COVID-19 diagnosis using AI
- Pleural and Pulmonary Diseases
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
University Medical Center Groningen
2016-2025
University of Groningen
2016-2025
Medisch Spectrum Twente
2024
University of Twente
2014-2024
RELX Group (United States)
2018
London Borough of Camden
2018
Screening for a high cardiovascular disease (CVD) risk followed by preventive treatment can potentially reduce coronary heart disease-related morbidity and mortality. ROBINSCA (Risk Or Benefit IN CArdiovascular disease) is population-based randomized controlled screening trial that investigates the effectiveness of CVD in asymptomatic participants using Systematic COronary Risk Evaluation (SCORE) model or artery calcium (CAC) scoring. This study describes distributions trial.Individuals at...
Lung cancer, chronic obstructive pulmonary disease (COPD), and coronary artery (CAD) are expected to cause most deaths by 2050. State-of-the-art computed tomography (CT) allows early detection of lung cancer simultaneous evaluation imaging biomarkers for the stages COPD, based on density bronchial wall thickness, CAD, calcium score (CACS), at low radiation dose. To determine cut-off values positive tests elevated risk presence is one major tasks before considering implementation CT screening...
Introduction A teachable moment for preventive behavioural change can occur when asymptomatic individuals receive their cardiovascular disease screening result. This study investigated prevention-seeking behaviour and compliance with treatment of participants the population-based Risk Or Benefit IN Screening CArdiovascular (ROBINSCA) trial after receiving a Methods Asymptomatic Dutch ( n = 43,447) were randomly assigned (1:1:1) to by either traditional risk assessment (intervention arm A),...
Background This population-based study aimed to identify the risk factors for lung nodules in a Western European general population. Methods We quantified presence or absence of among 12 055 participants Dutch ImaLife (Imaging Lifelines) (age ≥45 years) who underwent low-dose chest computed tomography. Outcomes included 1) at least one solid nodule (volume ≥30 mm 3 ) and 2) clinically relevant ≥100 ). Fully adjusted multivariable logistic regression models were applied overall stratified by...
Background Most of the data regarding prevalence and size distribution solid lung nodules originates from cancer screening studies that target high-risk populations or Asian general cohorts. In recent years, identification in non-high-risk populations, scanned for clinical indications, has increased. However, little is known about presence Northern European nonsmoking population. Purpose To study by age sex a Materials Methods Participants included nonsmokers (never former smokers)...
Peak velocity measurements are used to evaluate the significance of stenosis in patients with transposition great arteries after arterial switch operation (TGA ASO). 4D flow cardiovascular magnetic resonance (CMR) provides 3-directional encoding and full volumetric coverage may thus improve hemodynamic evaluation these patients. The aim this study was compare peak velocities measured by CMR 2D phase contrast (PC) gold standard Doppler echocardiography (echo) TGA ASO. Nineteen (mean age 13 ±...
Objective To address the relationship between tissue accumulation of advanced glycation end-products, assessed by skin autofluorescence (SAF), and subclinical atherosclerosis quantified with coronary artery calcium score (CACS) in general Dutch population. Methods A total 3,839 participants LifeLines Cohort Study without diabetes or cardiovascular disease were included this cross-sectional evaluation. They underwent SAF measurement cardiac computed tomography to measure CACS. Associations...
To evaluate detectability and quantification of coronary calcifications for CT with a tin filter spectral shaping. Phantom inserts 100 small 9 large calcifications, moving artificial artery 3 (speed 0–30 mm/s) were placed in thorax phantom simulating different patient sizes. The was scanned high-pitch spiral mode at kVp (Sn100 kVp), reference 120 kVp, electrocardiographic (ECG) gating. Detectability analyzed standard (130 HU) adapted thresholds. Sn100 yielded lower (9 % versus 12 %, p =...
To investigate the effect of slab thickness in maximum intensity projections (MIPs) on candidate detection performance a deep learning-based computer-aided (DL-CAD) system for pulmonary nodule CT scans. The public LUNA16 dataset includes 888 scans with 1186 nodules annotated by four radiologists. From those scans, MIP images were reconstructed thicknesses 5 to 50 mm (at intervals) and 3 13 2 intervals). architecture part DL-CAD was trained separately using various thicknesses. Based ten-fold...