A5103432305- Diabetes Management and Research
- Gestational Diabetes Research and Management
- Diabetes and associated disorders
- Alcohol Consumption and Health Effects
- Pancreatic function and diabetes
- Hemoglobinopathies and Related Disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Birth, Development, and Health
- Spectroscopy Techniques in Biomedical and Chemical Research
- Bariatric Surgery and Outcomes
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Metabolomics and Mass Spectrometry Studies
- Metabolism, Diabetes, and Cancer
- Pregnancy and preeclampsia studies
- Diet and metabolism studies
- Spectroscopy and Chemometric Analyses
- Cannabis and Cannabinoid Research
- Iron Metabolism and Disorders
- Eicosanoids and Hypertension Pharmacology
- Prenatal Screening and Diagnostics
- Thermoregulation and physiological responses
- Optical Imaging and Spectroscopy Techniques
- Ovarian cancer diagnosis and treatment
University of Utah
2009-2024
Syracuse University
2003-2024
Indiana University
2023
University of Illinois Chicago
2022
Illinois College
2022
University of Illinois Urbana-Champaign
2022
University of Miami
1981-2017
Howard Hughes Medical Institute
2017
Huntsman Cancer Institute
2017
Fred Hutch Cancer Center
2017
We studied the increased levels of hemoglobins AIa+Ib and AIc in five hospitalized diabetic patients to determine whether changes control would cause parallel these hemoglobins. Before diabetes mean fasting blood sugar for all was 343 mg per deciliter (range, 280 450), hemoglobin concentration 9.8 cent 6.8 12.1). During optimal 84 70 100), 5.8 4.2 7.6). Hemoglobin appears reflect best over previous weeks months. The periodic monitoring provides a useful way documenting degree glucose...
Clinical studies on the minor hemoglobins (hemoglobin A1a-c) have suggested that a novel adduct may form in people abusing alcohol. Such patients were found to an elevated concentration of hemoglobins, but normal or subnormal amounts glycosylated hemoglobin A1c) as determined by radioimmunoassay, Acetaldehyde, reactive metabolite ethanol, was postulated adducts with A change its chromatographic properties. At physiological concentrations, acetaldehyde stable extensive dialysis for several...
Endometriosis has been associated with an increased risk of ovarian cancer; however, the associations between endometriosis subtypes and cancer histotypes have not well-described.
Hemoglobin AIc concentration, fasting blood sugar, response to an oral glucose tolerance test, and skeletal muscle capillary basement membrane thickness were measured in diabetic patients. concentration correlates with both a test (r = 0.82, p less than 0.001) sugar 0.62, 0.001). The correlation of hemoglobin is independent (partial r 0.61, 0.005), whereas that probably reflects the relationship between levels 0.22, 0.05). do not correlate ( 0.15,
Abstract Background Laboratory animals are commonly used for evaluating the physiological properties of mammalian ovarian follicle and enclosed oocyte. The use different species to determine morphological relationship between oocyte has led a recognizable pattern follicular stages, but differences in size, diameter granulosa cell proliferation not consistent across species. In an effort better understand how these expressed multiple species, this investigation evaluates diameters mouse,...
Abstract Hemoglobin A1c (HbA1c) is a stable minor Hb variant formed in vivo by posttranslational modification glucose, originally identified using cation exchange chromatography, and containing primarily glycated N-terminal β-chains. However, the structure(s) of quantified species has not been elucidated, available methods lack reference standard. We used electrospray ionization mass spectrometry to determine extent glycation samples separated boronate affinity and/or chromatography....
Seven patients with diabetes mellitus were hospitalized and their blood sugar concentrations regulated as a result of fasting sugar, around meals, urinary hemoglobin AIc assays. Erythrocyte half-life measured by 51Cr increased in all from mean 27 days to 31 days, while levels decreased 10.1% 5.6%. Leukocyte adherence 28% 51%. Most striking the changes observed platelet function response epinephrine. The length secondary lag phase aggregation, after stimulus final concentration 70 µM...
We studied the effects of bacterial urease inhibitor acetohydroxamic acid on growth struvite stones in urinary tract. Eighteen patients who received (15 mg per kilogram body weight day, divided oral doses) for a mean 15.8 months were compared randomized double-blind study with 19 placebo 19.6 months. Seven given reached pre-determined end point: 100 cent increase two-dimensional surface area their stones. No patient had doubling stone size (P less than 0.01). Nine receiving drug and one...
This study aimed to determine differences in the rates of growth, endocrine- and calcium-related abnormalities various thalassemia syndromes North America treated with current therapies. Medical history, physical examinations blood urine collections were obtained from patients all age 6 years older Thalassemia Clinical Research Network. 361 subjects, 49% male, mean 23.2 (range 6.1-75 years) studied. Approximately 25% children adults, regardless syndrome, had short stature. Overall growth was...
The goal of this study was to evaluate a program resistance weight training on cardiovascular risk factors, blood glucose management, and overallstrength in diabetic subjects. A randomized crossover design performed eight male type I (insulin-dependent) subjects (mean ± SD age 31 3.5 yr, height 176 5.6 cm, body wt 80 15 kg, duration diabetes 12.3 9.8 insulin dose 24 U NPH/day 21 regular/day). consisted heavy-resistance 3 days/wk for 10 wk, concentrating the strengthening major muscle groups...
An attempt was made to improve the control of blood glucose in patients with insulin-dependent diabetes mellitus. Ten were studied over a period exceeding 8 mo outpatient department. Each patient taught monitor his or her own concentration and enrolled an exercise program. In addition, they calibrate insulin, food, terms response glucose. After 3 study, there significant decrease hemoglobin A1c (Hb A1c) values from mean 10.3 7.6%. Hb correlated well levels (r = 0.86). Dietary analysis...