A5100379914- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac tumors and thrombi
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiac electrophysiology and arrhythmias
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Diagnosis and treatment of tuberculosis
- Lysosomal Storage Disorders Research
- Ion channel regulation and function
- Rheumatoid Arthritis Research and Therapies
- Cellular transport and secretion
- Coronary Interventions and Diagnostics
- Cardiac Arrest and Resuscitation
- Musculoskeletal Disorders and Rehabilitation
- Topic Modeling
- Explainable Artificial Intelligence (XAI)
- Child Abuse and Related Trauma
- Tuberculosis Research and Epidemiology
- Medication Adherence and Compliance
NorthShore University HealthSystem
2022-2025
University of Chicago
2022-2025
North Memorial Medical Center
2024
University of Illinois Chicago
2020-2024
St. Luke's Hospital
2024
Clinical Research Solutions
2024
Queen's University
2023
University of Nevada, Las Vegas
2023
Grace (United States)
2022
Western University
2017
ABSTRACT Severe tricuspid regurgitation (TR) is associated with significant morbidity and mortality. Management of severe TR includes treatment the underlying cause(s), medical therapy less commonly surgical valve repair. Newer transcatheter repair devices show promise for those patients who remain symptomatic despite such efforts. The presence a Cardiac Implantable Electronic Device (CIED) leads across poses challenge from both diagnostic therapeutic standpoints. In this paper, we propose...
Tuberculosis (TB) remains a leading cause of death in children globally. It is recognized that human immunodeficiency virus (HIV) infection increases the risk developing TB, but our understanding impact HIV on mortality for treated TB limited. We aimed to identify predictors drug-susceptible TB. A retrospective analysis all (<15 years age) routinely between 2005 and 2012 Cape Town was conducted using programmatic electronic treatment database. Survival Cox regression used estimate hazard...
We develop a general framework for aligning large language models (LLMs) with business and economic objectives using available data. Our approach adapts an LLM to enhance the quality of decisions that can be expressed in terms text, e.g. persuasive messaging, while overcoming safety issues have hindered practical deployment LLMs. The core idea is fine-tune on data which credible causal inferences made. Using results from past A/B tests, we train convert worse-performing into...
NGLY1 Deficiency is an ultra-rare, multisystemic disease caused by biallelic pathogenic variants. The aims of this study were to (1) characterize the variants and clinical features largest cohort patients reported date, (2) estimate incidence disorder.The Grace Science Foundation collected genotypic data from 74 patients, which 37 also provided phenotypic data. We analyzed estimated in United States (U.S.).Analysis patient genotypes, including 10 previously unreported variants, showed strong...
Primary cardiac tumors account for only 0.3% of all tumors; these, lymphomas 2% primary tumors. Cardiac have a grim prognosis, often less than 1 year due to delays in diagnosis and treatment. MRI is the gold standard imaging We describe case 76-year-old man with no significant past medical history who presented emergency department large pericardial effusion that was found be consistent lymphoma on prior tissue diffuse B-cell lymphoma. The clinical radiological features are reviewed,...
The human ether-a-go-go-related gene (hERG) encodes for the pore-forming subunit of channel that conducts rapidly activating delayed K+ current (IKr) in heart. hERG is important cardiac repolarization, and reduction its expression plasma membrane due to mutations causes long QT syndrome type 2 (LQT2). As such, promoting a strategy rescue mutant function. In present study, we applied patch clamp, western blots, immunocytochemistry, quantitative reverse transcription polymerase chain reaction...
Background: As a growing rural Primary Stroke Center (PSC), we found acute stroke patients bypassing PSC via air care to receive at Comprehensive (CSC) without Large Vessel Occlusion (LVO) severity scale assessment. In collaboration with our local Emergency Medicine Services (EMS), aimed initiate LVO assessment routing algorithm enhance care. Our goal was improve pre-hospital assessments standard and algorithm. Further improving time sensitive utilizing resources appropriately during of...