- Neonatal and fetal brain pathology
- Fetal and Pediatric Neurological Disorders
- Innovations in Medical Education
- Neuroscience of respiration and sleep
- Neonatal Respiratory Health Research
- Metabolism and Genetic Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced Neuroimaging Techniques and Applications
- Acupuncture Treatment Research Studies
- Electrolyte and hormonal disorders
- Epilepsy research and treatment
- Neuroendocrine regulation and behavior
- Cardiac Arrest and Resuscitation
- Infectious Encephalopathies and Encephalitis
- Bacterial Infections and Vaccines
- Cerebrospinal fluid and hydrocephalus
- Simulation-Based Education in Healthcare
- Ultrasound in Clinical Applications
- Neurosurgical Procedures and Complications
- Amino Acid Enzymes and Metabolism
- Electronic Health Records Systems
- Social Media in Health Education
- Infant Development and Preterm Care
- Growth Hormone and Insulin-like Growth Factors
- Tuberous Sclerosis Complex Research
Harvard University
2024
Wake Forest University
2016-2022
Mackay Memorial Hospital
1994-2020
Mackay Medical College
2020
Atrium Health Wake Forest Baptist
2020
China Medical University Hospital
2009-2017
China Medical University
2007-2017
Taipei Medical University Hospital
2009-2013
Wan Fang Hospital
2005-2012
Taipei Medical University
2005-2012
Recent studies have shown that adult tissues contain stem/ progenitor cells capable of not only generating mature their tissue origin but also transdifferentiating themselves into other cells. Murine skin-derived precursor cells, for example, been described as unique, nonmesenchymal-like stem mesodermal and ectodermal neurogenic differentiation. Human-derived skin precursors are less well characterized. In this study, the isolation characterization adherent, mesenchymal cell-like from human...
We undertook a prospective ultrasound study of subependymal cyst formation in normal neonates. Twenty five 500 Chinese neonates (5%) were found to have cysts. Most these (18 25) showed no obvious perinatal insult. This suggests rather high incidence concealed intrauterine haemorrhage term
Baihui (GV20) is one of the most important acupoints Du meridian (the government vessel) and commonly used in neurology psychiatry as a distal point anorectal disorders by general practitioners. The anatomical relationship between scalp region acupoint underlying corresponding cortex remains obscure. In this study, we first prepared indicator for MRI scanning on GE 1.5 T excite machine mode suitable 3D reconstruction. Avizo software system (version 6.0, Mercury Computer Systems, Inc.,...
Ear acupuncture stimulation has been used for body weight reduction as early the 1970s. Several hypotheses have proposed in literature regarding its mechanism of action, among which are effects hypothalamic satiety center on decreased neuropeptide Y production. Here, we present another possible to account temporary and short-term ear treatment obesity, sympathetic autonomic nervous system. 14 female volunteers underwent a randomized clinical trial stimulation. A prospective, sham-point...
1. Intracellular recordings were made from sympathetic preganglionic neurons (SPNs) in transverse thoracolumbar spinal cord slices of 12- to 16-day-old rats. 2. A population SPNs exhibited spontaneous, rhythmic activities that can be grouped into regular firing, bursting, or tonic oscillatory mode; the spikes interspersed with subthreshold afterdepolarizing potentials (ADPs). 3. Spontaneous not abolished by excitatory amino acid antagonists 6-cyano-7-nitroquinoxoline-2,3-dione (CNQX, 10-20...
<h3>Objective</h3> In this study, we obtained relevant data from a nationwide cohort database to investigate the risk of attention deficit-hyperactivity disorder (ADHD) in children with history febrile seizures (FS). <h3>Methods</h3> We identified 1081 FS as case cohort, and date diagnosis was used an index date. Four controls were matched randomly each based on age, sex, urbanisation level, parents' occupation, applied Cox9s proportional hazards regression estimate HR CI FS-associated ADHD....
Six of 83 asphyxiated neonates showed a diffuse increase echodensity in bilateral thalami with or without other lesions the basal ganglia on sonographic examination. The thalamic image still had fairly high echogenecity compared surrounding brain parenchyma follow up examination and was hence termed bright thalamus. These six patients poor neurological outcome, including psychomotor retardation, spastic diplegia quadriplegia, microcephaly, failure to thrive, seizures, one death. thalamus is...
Acupuncture and moxibustion are used to treat pruritus atopic dermatitis. However, whether cold stimulation (defined as that the temperature conducted under skin temperature) of acupoints affects itching in experimental murine models remains unclear. The present study was designed determine therapeutic effects different thermal stimulations at Quchi acupoint (LI11) a model which scratching behaviour elicited by subcutaneous injection with pruritogenic agent (compound 48/80). Male ICR mice...
Point-of-care ultrasound (PoCUS) has been integrated into undergraduate medical education. The COVID-19 pandemic forced schools to evolve clinical rotations minimize interruption through implementation of novel remote learning courses. To address the students' need for education, we created a virtual PoCUS course our fourth-year class. We present details course's development, implementation, quality improvement processes, achievements, and limitations.A was 141 students. objectives included...
Objective The objective of the study was to evaluate factors associated with abnormal laboratory findings in patients visiting emergency department (ED) after having their first seizure. Methods We included ED seizures and divided them into groups based on normal results for serum levels sodium, potassium, calcium, glucose. evaluated differences age, sex, presence fever, gastrointestinal symptoms, duration pattern seizure, whether seizure still present at ED. Results 240 patients. Among...
The purpose of this study was to evaluate parenting stress in parents children with refractory epilepsy before and after their received vagus nerve stimulation (VNS) implantation.Parents completed the Parenting Stress Index (PSI) under a psychologist's assessment at least 12 months VNS implantation. PSI questionnaire measures two domains; parent domain seven subscales, child six. Age, gender, comorbidity, implantation date, seizure frequency, anticonvulsant history were obtained from reviews...