We evaluated the pharmacokinetics of intravitreally injected ranibizumab and aflibercept, their effects on VEGF in aqueous humor vitrectomized nonvitrectomized macaque eyes.Intravitreal (IVR; 0.5 mg/50 μL) or intravitreal aflibercept (IVA; 2 was into previously right eyes three macaques macaques. The left served as controls (nonvitrectomized, noninjected). Aqueous obtained from both just before injection days 1 3, weeks to 8 after IVR IVA. ranibizumab, concentrations were measured using...

This study examined the estimated prevalence rate of posttraumatic stress disorder (PTSD) symptoms and associated risk factors among Chinese adult survivors 7 to 8 months after 2008 Sichuan earthquake. The sample was recruited from 2 areas close epicenter but different distances. PTSD 55.6% 26.4% respectively in two areas. Loss a child strong predictive factor for parents. Other included female gender, loss parent, friends or neighbors, residential house damage collapse, proximity epicenter....

Bidirectional intimate partner violence (BIPV) refers to the co-occurrence of perpetration by both partners. BIPV has been analyzed using samples from different sociodemographic contexts but yet be fully explored in China. The present study employed a latent class approach identify patterns, rates prevalence, and associated risk factors among sample 1,301 heterosexual adult women mainland Five distinct patterns were identified, including (a) bidirectional psychological aggression, (b) all...

The current study assessed the estimated rate of depression and associated risk factors among survivors 8 months after 2008 Wenchuan earthquake in China. A stratified random sample 1514 participants was recruited from all temporary camp communities a county town 45 km away epicenter. 35.7%. severity depressive symptoms significantly with female sex, perceived livelihood security, loss family member, residential house damage or collapse, not living an urban area, whereas married status is...

Although the past two decades have witnessed substantial development of sex education in mainland China, Chinese society at large is both conservative and silent addressing sex-related issues, especially with children adolescents. Against this background, how do educators understand gender, sexuality education, they put their understandings into practice? In article, we explore these questions through semi-structured interviews seven national leaders, focus group discussions eight...

The Korean film My Sassy Girl was very popular among young people in urban China 2001. After the release of movie, new image "sassy girl" emerged different media. This study uses media sassy girl as a stimulus material interviews and focus groups to explore how men women make sense women's aggression dating relationships. qualitative is mainly based on two in-depth with 20 informants (13 female 7 male). sheds light competing multilayered discourses contemporary regarding gender, love, sex...

Distance learners often experience social isolation and impoverished interaction with their remote peers. To better understand the connections that distance are able to build peers, we interviewed them about whether how they perceive or cultivate one another. Our analysis reveals in an online learning environment formed experienced across different contexts technology affordances, what strategies practices enable inhibit these connections. We discuss implications of our findings for concepts...

Mitochondrial ferritin (FtMt) is believed to play an antioxidant role via iron regulation, and FtMt gene mutation has been reported in age-related macular degeneration (AMD). However, little known about FtMt's functions the retina any links AMD. In this study, we observed increase hypoxia-inducible factor-1α (HIF-1α) murine retinal pigment epithelium (RPE). overexpression ARPE-19 cells stabilized HIF-1α, increased secretion of vascular endothelial growth factor. Conversely, HIF-1α...

Introduction: School bullying is a serious social and public health problem. This article aims to explore the association between experiences of childhood abuse involvement in school bullying, especially considering mediating effects depression. Methods: The sample this study was 3059 students (1584 males 1475 females) aged from 12 20, eleven Chinese secondary schools, which included six middle four high one vocational both urban rural areas. multinomial logit regression linear were...

Abstract This article selects the critical moment of virginity loss in young Beijing women's lives to look at meaning sexual coercion dating relationships. The authors observed that many Chinese women presented their first experience sex as containing some elements were being described "minor," do not involve obvious physical force, but are unpleasant and regretful experiences loss. contributes a new understanding China sheds light on social transformation sexuality from Maoist era...

Although domestic violence has long been identified as a serious social problem in China, little is known about police officers’ attitudinal and behavioral tendencies toward such incidents. Drawing upon survey data collected from officers two Chinese provinces, this study assesses whether officer organizational factors are correlated to inaction intervention resolving family violence. More than quarter of often sometime did not take any action when responding favored most the least punitive...

Police attitudes toward domestic violence are essential occupational outlooks that can potentially shape police response to such violence. Studies on Chinese officers' scarce even after the enactment of Counter Domestic Violence Law (the DV Law) in China 2016. Drawing upon survey data collected from 1,139 officers three provinces (Hubei, Hunan, and Jiangsu) China, this study examined effect Law, organizational support policing DV, regional differences tolerance for DV. The results showed...

Schizophrenia is one of the foremost psychological illness around world, and recent evidence shows that inflammation oxidative stress may play a critical role in etiology schizophrenia. Andrographolide diterpenoid lactone from Andrographis paniculate, which has shown anti-inflammation anti-oxidative effects. In this study, we explored whether andrographolide can improve schizophrenia-like behaviors through its inhibition Phencyclidine (PCP)-induced mouse model We found abnormal behavioral...

This article considers cultural hierarchies that may shape practices of dating and partner choice among young women men in contemporary Beijing. Our research is mainly based on 43 in-depth interviews conducted Beijing over the past six years. The distinction between Beijingers waidiren (lit., outsiders) here serves as a framework to examine socioeconomic differentiation practices. We further complicate this by highlighting internal heterogeneity waidiren, including four groups: college...

Although there exists a growing body of research on female same-sex intimate partner violence (FSSIPV) as well bidirectional (BIPV) among lesbian women, much this literature focuses the IPV experience women living in Western societies such United States. The current study represents very first to explore BIPV China. In study, we analyze survey sample 225 self-identified China examine FSSBIPV patterns, pattern-specific rates, and risk factors FSSBIPV. Using Latent Class Analysis technique,...

Workplace sexual harassment (WSH) has been recognized in the literature as a serious problem for past 40 years. Since 2017, global #MeToo movement fostered local awareness of WSH and inspired researchers China to pay increasing attention. Guided by gender empowerment theory, this study investigated relationships between women’s responses targets (e.g., choosing avoidance or confrontation) both their perceptions equality knowledge relevant national laws. We used data from recent large-scale...

This article documents the brief history of cyber marriage on Chinese Internet and shows how in-game marriage, with its game codes regulations, turns out to be most visualized, institutionalized, heteronormative form by exploring players’ gender performativity, especially swapping male gamers. study sheds light youth subculture under influence new media consumer digital network in postsocialist China.