A5032152246- Veterinary Pharmacology and Anesthesia
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Veterinary Equine Medical Research
- Human-Animal Interaction Studies
- Thermal Regulation in Medicine
- Drug-Induced Adverse Reactions
- Inflammatory mediators and NSAID effects
- Hormonal and reproductive studies
- Ion channel regulation and function
- Spinal Cord Injury Research
- Inhalation and Respiratory Drug Delivery
- Nerve Injury and Rehabilitation
- Spinal Hematomas and Complications
- Adrenal Hormones and Disorders
- Pituitary Gland Disorders and Treatments
- Neurological Disorders and Treatments
- Potassium and Related Disorders
- Veterinary Orthopedics and Neurology
- Dermatology and Skin Diseases
- Veterinary Oncology Research
- Oral and Maxillofacial Pathology
- Lipoproteins and Cardiovascular Health
- Dental Anxiety and Anesthesia Techniques
- Cardiovascular Health and Disease Prevention
Alta Bates Summit Medical Center
2023-2024
Midwestern University
2020-2023
University of Saskatchewan
2017-2021
The Ohio State University
2005
Abstract Cystic fibrosis is caused by mutations in the gene encoding cystic transmembrane conductance regulator (CFTR) channel, which can result chronic lung disease. The sequence of events leading to disease not fully understood but recent data show that critical pathogenic event loss ability clear bacteria due abnormal airway surface liquid secretion (ASL). However, whether inhalation triggers ASL and this has never been tested. Here we show, using a novel synchrotron-based vivo imaging...
Abstract OBJECTIVE To evaluate sedative and behavioral effects of a client-administered preappointment protocol with PO gabapentin melatonin oral-transmucosal acepromazine (GMA protocol). ANIMALS 45 client-owned dogs between 1 12 years old that underwent standardize examinations February August 2021. METHODS In this clinical trial, history anxiety, fearfulness, and/or aggression during hospital visits were assessed videotaped before (baseline) after administration the GMA protocol. For...
Albuterol by inhalation (IH) is a common treatment for hyperkalemia in humans but its effect on blood potassium concentrations dogs unknown.Determine whether albuterol decreases healthy normokalemic and if effects are dose-dependent.Ten dogs.Prospective, crossover experimental study. sulfate was administered at low-dose (90 μg) phase I and, 7 days later, high-dose (450 II. Blood glucose (measured via gas analyzer) heart rates were obtained baseline then 3, 5, 10, 15, 30, 60, 90, 120, 180,...
Pain assessment in veterinary medicine is challenging. Uncertainty the ability to recognise pain animals contributes suboptimal analgesia. scales have been developed aid recognition. It unknown if such are routinely utilised practices.A survey using RedCap software was emailed veterinarians and technicians working practices across USA. This study aimed investigate whether scoring performed reasons use or not scales. One hundred forty-four participants were required estimate prevalence (95%...
Objectives The objective of this study was to evaluate the time decreased reactivity arytenoid cartilages in cats after application topical lidocaine. Methods One hundred and ten mixed-breed were randomly assigned one five groups based on between lidocaine stimulation larynx: 5 (T5), 15 (T15), 30 (T30), 45 (T45) or 60 (T60) s. Cats premedicated with dexmedetomidine, ketamine buprenorphine. Anesthesia induced propofol effect. Lidocaine 2% (2 mg/kg) applied topically vocal cords using a...
To determine the frequency, severity and duration of adverse events including myoclonus, pain on injection, hypersalivation, regurgitation apnoea after administration midazolam or saline followed by etomidate in hydromorphone premedicated dogs.Dogs undergoing elective dental prophylaxis soft tissue surgeries were enrolled this randomised trial. Dogs with 0.1 mg/kg IV. Sixty seconds later, 0.3 at an equivalent volume was administered that, 1.5 IV over 60 seconds. Additional doses 0.5 until...
The objective of this study was to evaluate owner assessment appetite, demeanor, and mouth soreness following dental extractions in dogs receiving either bupivacaine hydrochloride (BH) or liposomal encapsulated (LEB) for blocks. Thirty healthy, adult requiring were enrolled the study. All procedures completed with under general anesthesia. A non-steroidal anti-inflammatory drug administered subcutaneously preoperative period. Dogs randomly assigned receive BH LEB. An at end both first second...
Introduction Alzheimer's disease (AD) is the most common form of dementia and 6th leading cause death in US. Growing evidence supports a link between AD cardiovascular (CVD). Variant isoforms apolipoprotein E (APOE) are risk factors for both CVD. The APOE isoform, APOE3, has neutral developing AD, whereas APOE4 increases risk. Pathogenic alterations cardiac (C), aortic (TA) carotid artery (CA) function known to contribute neurodegenerative diseases including AD. Previous studies our lab have...
An 11-year-old female spayed domestic medium-hair cat presented for dental prophylaxis, at which time no oral mass was appreciated. Fifteen days after a cleaning, expanding the mucosa of rostral mandible identified. incisional biopsy revealed that infiltrated by neoplastic round-to-spindloid mesenchymal cells arranged in streams and small, dense aggregates consistent with an undifferentiated sarcoma. The patient managed medically approximately 6 months following diagnosis, but, owing to...
Introduction Alzheimer's disease (AD) is the most common form of dementia and 6th leading cause death in US. Growing evidence supports a link between AD cardiovascular (CVD). Variant isoforms apolipoprotein E (APOE) are risk factors for both CVD. The APOE isoform, APOE3, has neutral developing AD, whereas APOE4 increases risk. In order to study APOE-mediated processes, cerebral vessels were isolated from mice expressing human-ApoE targeted replacement APOE3 (B6.129P2-Apoetm2(APOE*3)Mae N8)...