- COVID-19 Clinical Research Studies
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Diabetes Management and Research
- Diabetes and associated disorders
- Urinary Tract Infections Management
- Drug-Induced Adverse Reactions
- Antibiotic Use and Resistance
- Long-Term Effects of COVID-19
- Clinical practice guidelines implementation
- Autoimmune Bullous Skin Diseases
- Contact Dermatitis and Allergies
- Mast cells and histamine
- Antifungal resistance and susceptibility
- Biochemical and Structural Characterization
- Medicine and Dermatology Studies History
- Bacterial biofilms and quorum sensing
- Emergency and Acute Care Studies
- Vitamin C and Antioxidants Research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Vectors
- Interprofessional Education and Collaboration
- Pharmaceutical and Antibiotic Environmental Impacts
- Problem and Project Based Learning
- Mycobacterium research and diagnosis
University of Washington
2007-2025
VA Puget Sound Health Care System
2019-2025
Museum of Heilongjiang Province
2021
University of California, Los Angeles
2017-2018
Seattle Children's Hospital
2008
Bristol Hospital
1957
Bristol Royal Hospital for Children
1954
OBJECTIVE To examine associations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection/coronavirus disease 2019 with incident diabetes. RESEARCH DESIGN AND METHODS We conducted a retrospective cohort study using Veterans Health Administration data. defined all patients without preexisting diabetes one or more nasal swabs positive for SARS-CoV-2 (1 March 2020–10 2021; n = 128,255) as exposed and those no swab laboratory tests 2020–31 2,679,851) unexposed. The index date...
(a) Constitutional.-In some individuals favourable condi tions are provided for the growth of staphylococci by virtue, example, a hormonal imbalance (especially androgen excess) or metabolic (with particular reference to sugar and water content skin). One cannot hope alter these factors permanently. (b) Immunity.-Active immunization against Staphylo coccus pyogenes is, on whole, disappointing. Favour able results have, however, been reported with vaccines toxoid, especially latter (Barber...
ABSTRACT The objective of this study was to investigate the trends and patterns resistance in β-lactamase-producing members family Enterobacteriaceae a children's hospital over 9-year period (1999 2007). Clinically significant isolates were screened for broad-spectrum β-lactams. strains likely be resistant subsequently confirmed by an inhibitor-based disc test. plasmid-mediated determinants these identified PCR vitro transformation, which successfully reproduced AmpC phenotype unrestricted...
Abstract Objective: To explore the progress that Veterans Health Administration has made to minimize impact of penicillin (PCN) allergy label, we determined proportion who reported a PCN-class at time hospitalization and described antibiotic use in hospitalizations with without allergy. Design: Cross-sectional study. Participants: National sample 6,541,299 acute care admissions between 2011 2022. Methods: We calculated prevalence allergies on admission used Poisson regression compare...
OBJECTIVE To identify preinfection risk factors for adverse outcomes among veterans with diabetes and coronavirus disease 2019 (COVID-19) infection. RESEARCH DESIGN AND METHODS We identified all Veterans Health Administration patients one or more positive nasal swab(s) severe acute respiratory syndrome 2 (1 March 2020–10 2021) (n = 64,892). examined associations of HbA1c glucose-lowering medication use hospitalization, intensive care unit (ICU) admission, mortality at 30 days using logistic...
deserves special comment.This disease is a primary degeneration of the neuro-epithelium retina on hereditary basis, importance blood relationship among parents for manifestation having been established (Nettleship, 1907-8).Cataracts often complicate retinitis pigmentosa and are always present in cases Werner's syndrome.If we accept view that belongs to group diseases which have this common, cells tissues affected become prematurely senile (Verhoeff, 1931), then cataracts, common two...
Risk factors and mediators of associations diabetes with COVID-19 outcomes are unclear.We identified all veterans receiving Department Veterans Affairs healthcare ≥1 positive nasal swab for SARS-CoV-2 (28 February-31 July 2020; n=35 879). We assessed (with without insulin use) hospitalization, intensive care unit (ICU) admission, or death at 30 days, hazard until the censoring date. Among participants (n=13 863), we examined hemoglobin A1c antihyperglycemic medication use outcomes. estimated...
Purpose: To use the 2010 to 2011 data collected by structured chart review provide a detailed up-to-date description of epidemiology and microbiology sepsis syndromes. Methods: Prospective observational study conducted at university-affiliated urban teaching hospital level-1 trauma burn center. All adult patients who triggered Code Sepsis in emergency department (ED) between January December were included. Results: One hundred eighty four presented with verified syndrome ED during studied...
To estimate associations of statin use with hospitalisation, intensive care unit (ICU) admission and mortality at 30 days among individuals without a positive test for SARS-CoV-2. Retrospective cohort study. US Veterans Health Administration (VHA). All veterans receiving VHA healthcare ≥1 nasal swab SARS-CoV-2 between 1 March 2020 10 2021 (cases; n=231 154) comparator group controls comprising all who did not have but clinical lab performed during the same time period (n=4 570 252)....
Journal Article PORPHYKIA CUTANEA TARDA FOLLOWING JAUNDICE.: Report of Two Cases. Get access L. G. TULLOCH, M.D., M.D. United Bristol Hospitals Search for other works by this author on: Oxford Academic Google Scholar K. P. Warin, M.R.C.P. British Dermatology, Volume 69, Issue 3, 1 March 1957, Pages 82–85, https://doi.org/10.1111/j.1365-2133.1957.tb13233.x Published: 01 1957
Abstract Objectives: To describe the association between duration of antimicrobial prophylaxis (AMP) and 30-day surgical site infection (SSI), 7-day acute kidney injury (AKI), 90-day Clostridioides difficile (CDI), prolonged hospitalization, reoperation after lumbar spine surgery for noninfectious indications, to report adherence current guidelines. Design: Survey. Participants setting: The study cohort comprised 6,198 patients who underwent indications across 137 Veterans’ Health...
Estimated excess acute-care length of stay and extra cost testing-based versus symptom-based isolation strategies among veterans hospitalized with coronavirus disease 2019 (COVID-19) discharging to a congregate setting - Volume 42 Issue 3
The Clinical and Laboratory Standards Institute (CLSI) recently lowered minimum inhibitory concentration (MIC) ciprofloxacin (CIP) levofloxacin (LEV) breakpoints for Enterobacteriaceae. These revisions are based on pharmacokinetic-pharmacodynamic attainment analyses, which may not accurately predict clinical outcomes all infections. We evaluated the of patients receiving CIP or LEV treatment bacteremia caused by Enterobacteriaceae isolates considered intermediate resistant to these agents...
<b>Objective: </b>To identify pre-infection risk factors for adverse outcomes among Veterans with diabetes mellitus and COVID-19 infection. <p><b> </b></p> <p><b>Research design methods: </b>We identified all Health Administration patients ≥1 positive nasal swab SARS-CoV-2 (March 1, 2020–March 10, 2021) (n=64,892). We examined associations of HbA1c glucose-lowering medication use hospitalization, ICU admission, mortality at 30 days using...
Abstract Objective: We examined the use of comprehensive and targeted polymerase chain reaction (PCR) Clostridioides difficile infection (CDI) among immunocompetent patients with without CDI risk factors across different outpatient settings. A priori, we expected higher to be associated testing reflect providers incorporating pretest in their choice test assay. Design: Retrospective analysis adult from clinic, emergency room, non-medically acute inpatient Setting: tertiary academic medical...
Background Strains of Klebsiella pneumoniae with multiple determinants drug resistance present a serious management problem. The that confer to cephalosporins and carbapenems are particular interest since these drugs frequently used in the treatment Enterobacteriaceae infections. Extended-spectrum β-lactamases (ESBLs), general, hydrolyze third-generation aztreonam (a monobactam). TEM, SHV, CTX-M families most prominent ESBLs. Carbapenem-hydrolyzing (carbapenemases) substrates ESBLs...