A5023896912- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- COVID-19 and healthcare impacts
- Reconstructive Surgery and Microvascular Techniques
- Nosocomial Infections in ICU
- Urinary Tract Infections Management
- Infection Control and Ventilation
- Antimicrobial Resistance in Staphylococcus
- COVID-19 and Mental Health
- Reconstructive Facial Surgery Techniques
- HIV Research and Treatment
- Wound Healing and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Clostridium difficile and Clostridium perfringens research
- Pediatric Urology and Nephrology Studies
- HIV/AIDS Research and Interventions
- Salivary Gland Tumors Diagnosis and Treatment
- Surgical site infection prevention
- Pneumonia and Respiratory Infections
- Sepsis Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Streptococcal Infections and Treatments
- Respiratory viral infections research
- Healthcare cost, quality, practices
University of Washington
2016-2025
Harborview Medical Center
2016-2025
Washington Center
2025
Washington State University Vancouver
2024
Office of the National Coordinator for Health Information Technology
2024
SIL International
2024
American Society For Engineering Education
2024
Seattle University
2012-2023
Harborview Injury Prevention and Research Center
2023
Neurological Surgery
2023
The coronavirus disease 2019 (COVID-19) pandemic initially manifested in the United States greater Seattle area and has rapidly progressed across nation past 2 months, with having highest number of cases world. Radiology departments play a critical role policy guideline development both for department institutions, specifically planning diagnostic screening, triage, management patients. In addition, radiology workflows, volumes, access must be optimized preparation expected surges patients...
Abstract Background UW Medicine was one of the first health systems to encounter and treat COVID-19 patients in United States, starting late February 2020. Objective Here we describe rapid rollout capabilities by Information Technology Services (ITS) support our clinical response pandemic provide recommendations for urgently consider, as they plan their own this potentially other future pandemics. Methods Our include establishing a hospital incident command structure that includes tight...
Despite modern antiseptic techniques, surgical site infection (SSI) remains a leading complication of surgery. However, the origins SSI and high rates antimicrobial resistance observed in these infections are poorly understood. Using instrumented spine surgery as model clean (class I) skin incision, we prospectively sampled preoperative microbiomes postoperative isolates cohort 204 patients. Combining multiple forms genomic analysis, correlated identity, anatomic distribution, profiles...
In the Seattle, Washington metropolitan area, where first case of novel coronavirus 2019 disease (COVID-19) in United States was reported (1), a community-level outbreak is ongoing with evidence rapid spread and high morbidity mortality among older adults long-term care skilled nursing facilities (SNFs) (2,3). However, COVID-19 residents senior independent assisted living communities, which do not live as closely together SNFs require services, has been described. During March 5-9, 2020, two...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused epidemic spread of disease 2019 (COVID-19) in the Seattle, Washington, metropolitan area, with morbidity and mortality concentrated among residents skilled nursing facilities. The prevalence COVID-19 older adults independent/assisted living is not understood.To conduct surveillance for SARS-CoV-2 describe symptoms staff an community.In March 2020, public health was conducted on site at assisted independent residence...
Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible virus that can infect healthcare personnel (HCP) and patients in settings. Specific care activities, particular, aerosol-generating procedures, may have higher risk of transmission. The rapid emergence global spread SARS-CoV-2 has created significant challenges facilities, particularly with severe shortages personal protective equipment (PPE) used to protect HCP. Evidence-based...
Two near-identical clinical Streptococcus pyogenes isolates of emm subtype emm43.4 with a pbp2x missense mutation (T553K) were detected. Minimum inhibitory concentrations (MICs) for ampicillin and amoxicillin 8-fold higher, the MIC cefotaxime was 3-fold higher than near-isogenic control isolates, consistent first step in developing β-lactam resistance.
Abstract Background Healthcare workers (HCWs) who serve on the front lines of coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe acute respiratory syndrome 2 (SARS-CoV-2) in some settings. Healthcare-acquired has reported similar epidemics, but there are limited data prevalence COVID-19 among HCWs and their associated clinical outcomes United States. Methods We established high-throughput employee testing centers Seattle, Washington, with...
It is difficult to define visual acuity, which changes from day and minute minute. In the discrimination of details, a part played by physical, physiologic psychologic factors. highest grade discriminations—the form sense—the factors play major rôle obscure ones. Visual acuity varies with illumination object surrounds—the general in subject sits—and adaptation eye. was once believed that two points separated one angle appear discrete. The images these lie about 0.0043 mm. apart on retina,...
Aerosols generated from metered dose inhalers may be highly charged. The aim of this study was to determine whether lining the walls a polycarbonate spacer device with an antistatic agent would result in increase drug output. effects multiple actuations into and increasing residence time within were also determined.The amount sodium cromoglycate contained particles various size available for inhalation (per 5 mg actuation) 750 ml determined by impinger measurement spectrophotometric...
In a prospective study, 31 patients with brown recluse spider bites were treated by either immediate surgical excision or the leukocyte inhibitor, dapsone, followed delayed excision. Patients matched for age, gender, and lesion size excluded if typical history physical findings not present. (N = 14), wound healing 5) objectional scarring 7) common complications. However, pretreatment treatment dapsone reduced incidence of complications 1) (p less than 0.05), while reducing need 1). There no...
A series of 100 patients in a general plastic surgery population were interviewed by standard format to determine their retention rate preoperative information given them. An overall recall, or rate, 35 percent was found.
SCHLENKER, JAMES D. M.D.; BUENO, REUBEN A. RICKETSON, GREER LYNCH, JOHN B. M.D. Author Information
Abstract Across 20 vaccine breakthrough cases detected at our institution, all (100%) infections were due to variants of concern (VOCs) and had a median Ct 20.2 (IQR, 17.1–23.3). When compared with 5174 contemporaneous samples sequenced in laboratory, VOCs significantly enriched among (P < .05).
Rees, Riley M.D.; Shack, R Bruce Withers, Edward Madden, James Franklin, John Lynch, J B M.D. Author Information
Adriamycin is an anti-cancer drug which has been recently released by the U. S. Food and Drug Administration to open market, its use increasing in frequency. Unfortunately, when it extravasates into soft tissues causes massive tissue necrosis about site of attempted intravenous administration. This develops at a slow rate, continues increase severity for several weeks, does not heal usual manner. The resulting ulcers are indolent, they remain source severe pain functional impairment many...
In wounds in rabbit ears, the application every 12 hours of an ointment containing epidermal growth factor appears to produce faster and better healing. The resulting epithelium is thicker more cellular than untreated ear wounds, fibroblasts appeared sooner during healing process. Less wound contracture occurred EFG-treated maturation earlier. healed that had been treated with EGF closely resembled surrounding normal tissue, producing less local deformity controls. It too early know whether...
On January 19, 2020, the first case of a patient with coronavirus disease 2019 (COVID-19) in United States was reported Washington State. February 29, infected severe acute respiratory syndrome 2 (SARS-CoV-2) passed away hospital Seattle-King County, COVID-19-related death States. That same day, skilled nursing and rehabilitation facility county that several its residents tested positive for SARS-CoV-2 many staff had symptoms compatible COVID-19. The University Medicine health system (UW...
The coronavirus disease 2019 (COVID-19) pandemic initially manifested in the United States greater Seattle area and has rapidly progressed across nation past 2 months, with having highest number of cases world. Radiology departments play a critical role policy guideline development both for department institutions, specifically planning diagnostic screening, triage, management patients. In addition, radiology workflows, volumes, access must be optimized preparation expected surges patients...