Martin C. Nwadiugwu

ORCID: 0000-0001-6788-8305
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About
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Research Areas
  • Alzheimer's disease research and treatments
  • Pharmaceutical Practices and Patient Outcomes
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Health Systems, Economic Evaluations, Quality of Life
  • Marine Biology and Environmental Chemistry
  • Wikis in Education and Collaboration
  • Bacillus and Francisella bacterial research
  • Bioinformatics and Genomic Networks
  • Zoonotic diseases and public health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Chronic Disease Management Strategies
  • Organometallic Compounds Synthesis and Characterization
  • Thyroid Cancer Diagnosis and Treatment
  • HIV-related health complications and treatments
  • Diabetes Management and Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Gene expression and cancer classification
  • Epigenetics and DNA Methylation
  • Artificial Intelligence in Healthcare and Education
  • Frailty in Older Adults
  • Pluripotent Stem Cells Research
  • Dementia and Cognitive Impairment Research
  • Expert finding and Q&A systems
  • Animal Disease Management and Epidemiology

Tulane University
2022-2025

University of Southern California
2021-2022

University of Nebraska at Omaha
2020-2022

University of Stirling
2020-2021

In recent years, several studies have provided insight on the functioning of brain which consists neurons and form networks via interconnection among them by synapses. Neural are formed interconnected systems neurons, two types, namely, Artificial Network (ANNs) Biological (interconnected nerve cells). The ANNs computationally influenced human used in modelling neural systems. reasoning foundations been useful anomaly detection, areas medicine such as instant physician, electronic noses,...

10.48550/arxiv.2101.08635 preprint EN cc-by arXiv (Cornell University) 2021-01-01

Understanding the current state of real-world Fast Healthcare Interoperability Resources (FHIR) applications (apps) will benefit biomedical research and clinical care facilitate advancement standard. This study aimed to provide a preliminary assessment these apps' clinical, technical, implementation characteristics.We searched public repositories for potentially eligible FHIR apps surveyed app implementers other stakeholders.Of 112 surveyed, most focused on (74) or (45); were implemented...

10.1093/jamiaopen/ooac077 article EN cc-by JAMIA Open 2022-10-04

Current treatments for Alzheimer’s disease (AD) focus on slowing memory and cognitive decline, but none offer curative outcomes. This study aims to explore curate the common properties of active, drug-like molecules that modulate glycogen synthase kinase 3β (GSK-3β), a well-documented with increased activity in tau hyperphosphorylation neurofibrillary tangles—hallmarks AD pathology. Leveraging quantitative structure–activity relationship (QSAR) data from PubChem ChEMBL databases, we employed...

10.3390/ijms25052646 article EN International Journal of Molecular Sciences 2024-02-24

Fortifying our preparedness to cope with biological threats by identifying and targeting virulence factors may be a preventative strategy for curtailing infectious disease outbreak. Virulence evoke successful pathogenic invasion, the science technology of genomics offers way them, their agents evolutionary ancestor. Genomics possibility deciphering if release pathogen was intentional or natural observing sequence annotated data causative agent, evidence genetic engineering such as cloned...

10.1136/postgradmedj-2021-139916 article EN cc-by Postgraduate Medical Journal 2022-01-12

Glycemic variability (GV) is an obstacle to effective blood glucose control and autonomous risk factor for diabetes complications. We, therefore, explored sample data of patients with mellitus who maintained better amplitude glycemic fluctuations compared their disease outcomes groups having poor control. A retrospective study was conducted using electronic hemoglobin A1C (HbA1c) values five recent time points from Think Whole Person Healthcare (TWPH). The grid analysis (CVGA) plot...

10.3390/jcm10071477 article EN Journal of Clinical Medicine 2021-04-02

The follicular thyroid carcinoma (FTC) and adenoma (FTA) are malignant benign neoplasms, respectively. MicroRNA (miRNA) expressions have been touted as an indicator for prognostic outcome in cancer. study objective was to explore genes suppressed by miRNA-21-3p miRNA-21-5p potential therapeutic insights. Differentially expressed their functional enrichment were obtained from 25 FTA 27 FTC gene microarray dataset GSE82208 using R Bioconductor tools. miRNA target sites miR-TarBase database. A...

10.1177/1176935120948474 article EN cc-by-nc Cancer Informatics 2020-01-01

Pseudogenes have been classified as functionless and their annotation is an ongoing problem. The Adh6-ps1-a mouse pseudogene belonging to the alcohol dehydrogenase gene complex (Adh) was analyzed review conservation, homology, expression, interactions identify any role it plays in disease phenotypes using bioinformatics databases. Results showed that Adh6-ps1 2 transcripts (processed unprocessed) which may emerged from a transposition duplication event, respectively, induced inversions (Uox...

10.1177/11779322211040591 article EN cc-by-nc Bioinformatics and Biology Insights 2021-01-01

Trimethyltin-induced cerebellar damage on adult male Wistar rats.

10.21931/rb/2018.03.04.6 article EN Bionatura 2018-11-15

As social media influence becomes popular, having an understanding of why some posts are more highly followed thanothers as viewed from the perspective those leading post allows us to gain insight on how followership is beinginfluenced. A

10.33965/ict_csc_wbc_2020_202008l021 article EN 2020-07-21

Fortifying our preparedness to cope with biological threats by identifying and targeting virulence factors may be a preventative strategy for curtailing infectious disease outbreak. Virulence evoke successful pathogenic invasion, the science technology of genomics offers way them, their agents evolutionary ancestor. Genomics possibility deciphering if release pathogen was intentional or natural observing sequence annotated data causative agent, evidence genetic engineering such as cloned...

10.1136/postmj/postgradmedj-2021-139916 article EN PubMed 2022-01-12

As social media influence become increasingly popular, understanding why some posts are highly followed than others, especially from the perspective of those leading discussion allows us to gain insight on how followership is being influenced. A qualitative study eight participants active discussions Quora was conducted using semi-structured in-depth interviews, by thematic analysis. The open coding method used iteratively code related answers develop themes. Results suggest that copyright...

10.3389/fcomp.2021.582242 article EN cc-by Frontiers in Computer Science 2021-03-29
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