A5045652283- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Hematopoietic Stem Cell Transplantation
- CAR-T cell therapy research
- Chronic Lymphocytic Leukemia Research
- Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Chronic Myeloid Leukemia Treatments
- Protein Degradation and Inhibitors
- Mesenchymal stem cell research
- Complement system in diseases
- Immunodeficiency and Autoimmune Disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Immune Cell Function and Interaction
- Renal Transplantation Outcomes and Treatments
- Viral-associated cancers and disorders
- Diabetes and associated disorders
- Cytomegalovirus and herpesvirus research
- Peptidase Inhibition and Analysis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cancer Mechanisms and Therapy
- Melanoma and MAPK Pathways
- Glioma Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- Oral health in cancer treatment
Mayo Clinic
2020-2025
WinnMed
2024
The Barbara Ann Karmanos Cancer Institute
2022-2023
Wayne State University
2022-2023
Mayo Clinic in Arizona
2020-2023
University of Arkansas for Medical Sciences
2013-2021
Suraj Eye Institute
2007-2010
Depression and anxiety are some of the most common mental health disorders in world contributing to significant morbidity mortality. Past treatments have focused primarily on treating depression anxiety. However, there is an urgent need detect chronic stress states potentially intervene using just-in-time personalized interventions. Modern technology has revolutionized our ability passively measure various biological physiological signals. In daily lives, we generate amounts electronic data...
Transplant-associated thrombotic microangiopathy (TA-TMA) is an endothelial dysfunction syndrome observed after allogeneic hematopoietic cell transplant (alloHCT). Our aim was to externally validate the impact of high-risk features on clinical outcomes adult patients meeting updated TA-TMA harmonizing criteria. Between 2005 and 2022, 99 were diagnosed with at Mayo Clinic Rochester (incidence 6.2%) a median 137 days post alloHCT (IQR: 34-283 days). The development associated inferior overall...
BackgroundBecause relatively little has been known about the actual prevalence of hypertension in India, particularly for its rural population, we investigated arterial a Indian population.
Light chain deposition disease (LCDD) is characterized by monotypic immunoglobulin depositions which will eventually lead to loss of organ function if left untreated. While the kidney almost always affected, presence and degree LCDD in other organs vary. Ten thirty percent patients have underlying Multiple Myeloma (MM), yet outcome prognostic markers this particular patient group are still lacking. Here, we analyzed 69 with MM biopsy proven report on renal extra-renal involvement its impact...
Patients with newly diagnosed acute myeloid leukemia (ND-AML) derive variable survival benefit from venetoclax + hypomethylating agent (Ven-HMA) therapy. The primary objective in the current study was to develop genetic risk models that are predictive of and applicable at time diagnosis after establishing treatment response. Among 400 ND-AML patients treated Ven-HMA Mayo Clinic, 247 (62%) achieved complete remission (CR) or without (CRi) count recovery. Multivariable analysis-derived hazard...
Large pericardial effusion (LPE) and tamponade are purported manifestations associated with atypical chronic graft-versus-host disease (cGVHD); however, their temporal association GVHD, management, impact on overall outcome not well established. We report a retrospective analysis of 38 patients who developed LPE from cohort 1265 (3.00%) age ≥18 years underwent allogeneic hematopoietic cell transplantation (alloHCT) at Mayo Clinic between March 1993 August 2020. The median patient the time...
Immune checkpoint inhibitors (ICIs) and brentuximab vedotin (BV) are novel agents for classic Hodgkin lymphoma, including relapse after autologous stem cell transplant (ASCT). However, their impact on survival post-ASCT relapse, in comparison with conventional therapy, is less known due to the lack of randomized controlled trials. Clinical characteristics outcomes 115 patients (or progression) ASCT studied. After a median follow-up 8.59 years from progression-free (PFS) overall (OS) were...
Autologous hematopoietic stem cell transplant (AHSCT) is the standard of care in treatment multiple myeloma worldwide. Infections are one most common complications chemotherapy regimen and AHSCT. Thrombotic microangiopathies rare but potentially life-threatening infections associated with thrombocytopenic purpura hemolytic uremic syndrome (HUS) two type thrombotic microangiopathies. The HUS classically related to diarrheal illness such as E. coli strain O157: H7 that produce Shiga-like...
Patients with renal cell carcinoma (RCC) often remain asymptomatic until the disease is advanced, about 25% presenting at an advanced stage. We present a case of metastatic RCC treated combination ipilimumab and nivolumab complete radiological pathological response. Currently, preferred option for intermediate- poor-risk patients clear stage IV RCC.