Joseph B. Zwischenberger

ORCID: 0000-0001-6812-2571
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About
Contact & Profiles
Research Areas
  • Mechanical Circulatory Support Devices
  • Respiratory Support and Mechanisms
  • Cardiac Arrest and Resuscitation
  • Cardiac Structural Anomalies and Repair
  • Congenital Heart Disease Studies
  • Tracheal and airway disorders
  • Airway Management and Intubation Techniques
  • Pleural and Pulmonary Diseases
  • Transplantation: Methods and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Esophageal and GI Pathology
  • Esophageal Cancer Research and Treatment
  • Thermal Regulation in Medicine
  • Surgical Simulation and Training
  • Cardiac and Coronary Surgery Techniques
  • Neonatal Respiratory Health Research
  • Ultrasound and Hyperthermia Applications
  • Trauma Management and Diagnosis
  • Burn Injury Management and Outcomes
  • Organ Transplantation Techniques and Outcomes
  • Gastric Cancer Management and Outcomes
  • Intensive Care Unit Cognitive Disorders
  • Cardiac Valve Diseases and Treatments
  • Inhalation and Respiratory Drug Delivery

University of Kentucky
2015-2024

Markey Cancer Center
2014-2023

Medical University of South Carolina
2020-2022

The University of Texas Health Science Center at Houston
2022

University of Kentucky HealthCare
2012-2021

The University of Texas Medical Branch at Galveston
2001-2020

National Heart Lung and Blood Institute
2020

Society of Thoracic Surgeons
2006-2015

National Institutes of Health
2015

490 BioTech (United States)
2015

A prospective controlled randomized study of the use extracorporeal membrane oxygenation to treat newborns with respiratory failure was carried out using "randomized play-the-winner" statistical method. In this method chance randomly assigning an infant one treatment or other is influenced by outcome each patient in study. If more successful, patients are assigned that treatment. group 12 infants birth weight greater than 2 kg met objective criteria for high mortality risk. One conventional...

10.1542/peds.76.4.479 article EN PEDIATRICS 1985-10-01

Section:ChooseTop of pageAbstract <<METHODSRESULTSDISCUSSIONAPPENDIX: VENTILATOR MANA...ReferencesCITING ARTICLES

10.1164/ajrccm.165.6.2003052 article EN American Journal of Respiratory and Critical Care Medicine 2002-03-15

Each year thousands of patients require extracorporeal life support (ECLS) for a variety respiratory, cardiac, and emergency reasons. The ECLS registry, Federal Drug Administration approved control group, provides database approximately 37,000 from domestic international hospitals, with details about demographic factors, diagnosis, treatment, complications. report is circulated to Extracorporeal Life Support Organization members the goal providing feedback on each center's practices relative...

10.1097/mat.0b013e318190b6f7 article EN ASAIO Journal 2008-12-17

We are developing a high performance double lumen cannula (DLC) for minimally invasive, ambulatory and percutaneous paracorporeal artificial lung (PAL). The Wang-Zwische (W-Z) DLC was designed insertion into the Internal Jugular (IJ) vein with drainage open to both superior vena cava (SVC) inferior (IVC) maximizing venous drainage. A separate collapsible but nondistensible membrane infusion right atrium (RA) achieves minimal recirculation allowing total gas exchange. W-Z prototypes made by...

10.1097/mat.0b013e31818c69ab article EN ASAIO Journal 2008-11-01

Correct placement of the Avalon Elite Bicaval Dual Lumen catheter (Avalon Laboratories, LLC, CA) for single-site venovenous extracorporeal membrane oxygenation (VV ECMO) is safe using image guidance. Using this technique, 26 27 patients (96%) had uneventful cannula in right internal jugular vein. One patient a superior vena cava injury during serial dilation, and another required repositioning improved flows. We recommend both fluoroscopy transesophageal echocardiogram (TEE) training...

10.1097/mat.0b013e3182155fee article EN ASAIO Journal 2011-04-15

Objectives: We sought to determine the long-term survival of patients treated for bronchial carcinoid tumors and whether lesser resections have had an effect on outcomes. Methods: conducted a retrospective, multi-institutional review surgically primary since 1980. Operative approach, pathologic stage, histology, surgical complications, tumor recurrence, were assessed. Results: There 50 men 89 women with mean age 52.2±17.4 58.9±13.3 years, respectively (P=0.021). Men more likely be current or...

10.1016/s1010-7940(00)00493-0 article EN European Journal of Cardio-Thoracic Surgery 2000-08-01

Intracranial hemorrhage is a complication of extracorporeal membrane oxygenation for the treatment neonatal respiratory failure. A retrospective review 35 neonates treated with was performed; ten had intracranial hemorrhage. Infants lower birth weights and were gestationally younger than infants Eight eight less weeks' gestational age sustained Six died immediately after stopped. Two lived 1 year. 27 older 34 One child normal, other at 18 months age. Based on results this study, risk appears...

10.1542/peds.78.4.699 article EN PEDIATRICS 1986-10-01

Patients with severe cardiac or pulmonary failure who require transport to specialized hospitals currently pose a challenge. Mechanical support in the form of extracorporeal membrane oxygenation (ECMO) may increase safety transporting such patients an institution where they will have access advanced medical therapy. Over 2.5 years, 17 were successfully cannulated and placed on simplified ECMO circuit at other institutions transported via ambulance our hospital. Fourteen acute respiratory...

10.1097/mat.0b013e3182238b55 article EN ASAIO Journal 2011-09-01

The severe acute respiratory syndrome-CoV-2 is an emerging viral pathogen responsible for the global coronavirus disease 2019 pandemic resulting in significant human morbidity and mortality. Based on preliminary clinical reports, hypoxic failure complicated by distress syndrome leading cause of death. Further, septic shock, late-onset cardiac dysfunction, multiorgan system are also described as contributors to overall Although extracorporeal membrane oxygenation other modalities mechanical...

10.1161/circheartfailure.120.007175 article EN mit Circulation Heart Failure 2020-05-01
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