A5101702559- Esophageal Cancer Research and Treatment
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Pancreatic and Hepatic Oncology Research
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
- Cancer Immunotherapy and Biomarkers
- Ear and Head Tumors
- Brain Metastases and Treatment
- Cancer survivorship and care
- Metastasis and carcinoma case studies
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Diagnosis and Treatment
- Immune Cell Function and Interaction
- Childhood Cancer Survivors' Quality of Life
- Multiple Myeloma Research and Treatments
- Protein Degradation and Inhibitors
- Family Support in Illness
- Immunotherapy and Immune Responses
Weifang People's Hospital
2021-2024
Shandong University
2019-2024
Shandong First Medical University
2020
Shandong Tumor Hospital
2020
Abstract Objectives This research aimed to develop a radiomics-clinical nomogram based on enhanced thin-section CT radiomics and clinical features for the purpose of predicting presence or absence metastasis in lymph nodes among patients with resectable esophageal squamous cell carcinoma (ESCC). Methods study examined data 256 ESCC, including 140 cases node metastasis. Clinical information was gathered each case, were derived from contrast-enhanced help 3D slicer. To validate risk factors...
Purpose: Lymphocytes are central players in systemic anti-tumor immune responses. In this study, we aimed to identify the relationship between absolute lymphocyte count (ALC) nadir during definitive radiotherapy (RT) and survival outcomes patients with esophageal squamous cell carcinoma (ESCC), as well evaluate effect of RT parameters on ALC RT. Materials methods: We retrospectively reviewed 189 stage I-IVA ESCC, who were treated at a single institution 2012 2015. values assessed before,...
Abstract Purpose Few studies have reported the impact of clinical response patients with Esophageal Carcinoma to chemoradiotherapy (CRT). Our study examines association between and pretreatment variables, survival, patterns failure, benefit consolidation chemotherapy in subjects esophageal squamous cell carcinoma (ESCC) receiving CRT. Methods Data from ESCC treated at Shandong Cancer Hospital January 2013 December 2016 were analyzed retrospectively. By definition, we considered a poor as...
Abstract Background The spleen plays an important role in systemic antitumor immune response, but whether imaging features have predictive effect for prognosis and status was unknown. aim of this study to investigate computed tomography (CT)‐based radiomics predict the patients with esophageal squamous cell carcinoma (ESCC) underwent definitive radiotherapy (dRT) try find its association immunity. Methods This retrospective included 201 ESCC who received dRT. Patients were randomly divided...
Nuclear protein in testis (NUT) cancers, also known as midline tends to occur organs near the midline, such nasal sinuses and mediastinum. NUT carcinoma is very rare has a poor prognosis.
Background: The present study aimed to determine the prognostic value of size metastatic lymph node (LN) in non-surgical patients with esophageal squamous cell carcinoma (ESCC). Methods: Three hundred seventy-six ESCC treated definitive (chemo-) radiotherapy from January 2013 March 2016 were reviewed. We analyzed potential associations nodal responses, patterns failure, and survival. Log-rank testing Cox proportional hazards regression models used assess impact clinical factors on Results:...
Nasopharyngeal carcinoma is an endemic head and neck cancer in Southern China. The common metastases organs involve bone, lung, liver. Metastases the dura at multiple locations brain after a diagnosis of nasopharyngeal are extremely rare.We present case 66-year-old man who initially complained nasal congestion, epistaxis, hearing impairment. biopsy nasopharynx lesion showed basaloid squamous cell carcinoma. Eight months conventional therapy, patient was admitted to our hospital again with...
Background Esophageal squamous cell carcinoma is the predominant subtype of esophageal cancer in China and so differs from presentations Western countries. Common metastatic locations include liver, lung, bone, brain. In contrast, metastases subcutaneous soft tissue are exceedingly rare. Case presentation We present experience a 57-year-old man with complaint hand leg dysfunction on right side. He had past medical history carcinoma. Further imaging workup revealed solitary brain metastasis,...
Clinical T4 stage (cT4) esophageal tumors are difficult to be surgically resected, and definitive radiotherapy (RT) or chemoradiotherapy (dCRT) remains the main treatment. The study aims analyze association between status of lymph node (LN) metastasis survival outcomes in cT4 squamous cell carcinoma (ESCC) patients that underwent treatment with dCRT RT. This retrospective analyzed clinical data 555 ESCC treated RT at Shandong Cancer Hospital Liaocheng People's from 2010 2017. Kaplan-Meier...
Objective To explore the relationship between HLA-B allele polymorphisms and nasopharyngeal carcinoma (NPC) in Xinjiang, China its clinical significance. Methods A total of 226 patients were assigned to NPC group, while 207 healthy volunteers control group. PCR amplification with sequence-specific primers was used determine alleles. Comparison frequency above two groups, Han Uygur populations, various characteristics made by chi-square test. The Kaplan-Meier method calculate survival...
Abstract Background Whether adjuvant chemotherapy (AC) after concurrent chemoradiotherapy (CCRT) could provide benefit to esophageal squamous cell carcinoma (ESCC) patients is controversial. Therefore, we decided investigate the potential of AC CCRT for ESCC and identify biomarkers predictive a clinical benefit. Methods We retrospectively analysed data with stage II–IVa who underwent CCRT. Then, compared received (CCRT + group) those alone group). Propensity score analysis, subgroup analysis...