A5052124444- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Electrochemical Analysis and Applications
- Ionic liquids properties and applications
- Asymmetric Synthesis and Catalysis
- Molecular spectroscopy and chirality
- Crystallography and molecular interactions
- Chemical Synthesis and Analysis
- Molecular Junctions and Nanostructures
- Molecular Sensors and Ion Detection
- Advanced battery technologies research
- Analytical Chemistry and Chromatography
- Electrochemical sensors and biosensors
- Fluorine in Organic Chemistry
- Conducting polymers and applications
- Photoreceptor and optogenetics research
- Cyclopropane Reaction Mechanisms
- Organic and Molecular Conductors Research
- Chemical Reaction Mechanisms
- Lanthanide and Transition Metal Complexes
- Synthesis of Indole Derivatives
- Origins and Evolution of Life
- Luminescence and Fluorescent Materials
- Catalytic Cross-Coupling Reactions
- Biotin and Related Studies
Université Paris Cité
2009-2024
Centre National de la Recherche Scientifique
2008-2024
Laboratoire d'Electrochimie Moléculaire
2014-2024
Délégation Paris 7
2014-2019
Sorbonne Paris Cité
2014-2019
Délégation Paris 6
2014-2017
Laboratoire de Chimie de Coordination
2014
Université de Toulouse
2014
3M (United States)
2014
Université de Montréal
2011-2013
Due to their eco-sustainability and versatility, organic electrodes are promising candidates for large-scale energy storage in rechargeable aqueous batteries. This is notably the case of hybrid batteries that pair low voltage a zinc anode with high quinone-based (or analogue quinone-based) cathode. However, mechanisms governing charge-discharge cycles remain poorly understood even matter debate controversy. No consensus exists on charge carrier mild electrolytes, especially when working an...
A new methodology for the asymmetric synthesis of quaternary α-substituted amino acids using memory chirality has been developed. The strategy utilizes dynamic axial tertiary aromatic amides to memorize initial an α-amino acid during enolization step. Starting from five different l-amino acids, corresponding oxazolidin-5-ones containing a amide group have synthesized in one step and then alkylated with various electrophiles, good yields enantioselectivities (up 96% up >99% after...
The halogen bond donor properties of iodo-tetrathiafulvalene (I-TTF) can be electrochemically switched and controlled via reversible oxidation in the solution phase. Interestingly activation only one single yielded already a strong selective interaction, quantified by cyclic voltammetry. standard potentials redox couples I-TTF(0/1+) I-TTF(1+/2+) were observed to shift upon addition halides. These anions selectively stabilize cationic I-TTF species through bonding polar liquid electrolytes....
Ionic liquid self-assembled monolayers (SAM) were designed and applied for binding streptavidin, promoting affinity biosensing enzyme activity on gold surfaces of sensors. The synthesis 1-((+)-biotin)pentanamido)propyl)-3-(12-mercaptododecyl)-imidazolium bromide, a biotinylated ionic (IL-biotin), which self-assembles film, afforded streptavidin sensing with surface plasmon resonance (SPR). IL-biotin-SAM efficiently formed full monolayer....
A new methodology for the asymmetric synthesis of quaternary α-substituted amino acids using memory chirality has been developed. This strategy employs dynamic axial tertiary aromatic amides to memorize initial an α-amino acid during enolization step. Starting from l-valine, oxazolidin-5-one containing a amide was synthesized in one step and then alkylated with various electrophiles good yield enantioselectivity (up 96%). Quaternary products can be obtained enantiomerically pure by...
Cyclic voltammetry has been used for the first time to probe and activate non-covalent halogen bonding <italic>via</italic> redox switching in solution.
Frozen: The spontaneous crystallization of an achiral compound in a chiral conformation is used as the unique source chirality absolute asymmetric synthesis tertiary amino acids. dynamic axial aromatic amides frozen crystal (see picture) and responsible for stereoselectivity deprotonation/alkylation scheme). α-Amino acid derivatives are synthesized up to 96 % ee.
A variety of imaging technologies are now routinely used in the medical field, their use being continuously enlarged through development contrast agents. Recently nanoparticles (NPs) proved efficient to improve <italic>in vivo</italic> by increasing and targeting capabilities. The current trend is focused on dual agents combining two or more functionalities same NP. Motivated this new challenge we developed FeBi NPs as nanomaterials with potential application a agent for MRI CT imaging. In...
Due to their eco-sustainability and versatility, organic electrodes are promising candidates for large-scale energy storage in rechargeable aqueous batteries. This is notably the case of hybrid batteries that pair low voltage a zinc anode with high quinone-based (or analogue quinone-based) cathode. However, mechanisms governing charge-discharge cycles remain poorly understood even matter debate controversy. No consensus exists on charge carrier mild electrolytes, especially those containing...
Due to their eco-sustainability and versatility, organic electrodes are promising candidates for large-scale energy storage in rechargeable aqueous batteries. This is notably the case of hybrid batteries that pair low voltage a zinc anode with high quinone-based (or analogue quinone-based) cathode. However, mechanisms governing charge-discharge cycles remain poorly understood even matter debate controversy. No consensus exists on charge carrier mild electrolytes, especially those containing...
Five <italic>N</italic>-phenylviologen (PV<sup>2+</sup>) derivatives have been synthesized and their electrochemical behavior in the presence of halide anions has studied. Further investigations were carried out by <sup>1</sup>H <sup>19</sup>F NMR spectroscopy at different chloride concentrations. This is first time a systematic study combines cyclic voltammetry order to analyse contribution halogen bonding among various non-covalent interactions between iodinated...
The first Faraday Discussion on halogen bonding was held in the beautiful capital city of Canada, Ottawa, from 10<sup>th</sup> to 12<sup>th</sup> July, 2017.
Abstract Herein, a new molecular autocatalytic reaction scheme based on H 2 O ‐mediated deprotection of boronate ester probe into redox cycling compound is described, generating an exponential signal gain in the presence and reducing agent or enzyme. For such purpose, chemosensing probes built around naphthoquinone/naphthohydroquinone redox‐active core, masked by self‐immolative boronic protecting group, were designed. With these probes, typical kinetic traces with characteristic lags phases...
A simple anion metathesis in diluted aqueous carbonate at room temperature affords 1-(12-mercaptododecyl)-3-methyl-imidazolium (MDMI-HCO3) from MDMI salts self-assembled on gold films and nanoparticles. The properties of MDMI-SAM differ solution, for which the exchange reaction does not proceed.
Abstract Herein, we report the development of biohybrid catalysts that are capable catalyzing aldol reaction. The use biotinylated imidazolium salts in combination with racemic or enantiomerically pure catalytic anions allowed us to study adaptive and cooperative positioning anionic catalyst inside protein. Supramolecular encapsulation into avidin resulted good selectivity for reaction performed ionic liquid/water mixtures.
The properties of a surface modified with an ionic liquid self-assembled monolayer (IL-SAM) can be tuned by simply changing the deposition temperature. Mid-IR, SERS, and molecular modelling demonstrated that 1-(12-mercaptododecyl)-3-methylimidazolium bromide (MDMIBr) exhibited crystalline for temperatures below 25 °C. Above °C, aliphatic chain collapsed into disordered conformation. At 40 another phase transition occurs due to imidazolium group tilting parallel surface. Consequently,...
Here we report a simple autocatalytic organic reaction network based on the redox chemistry of quinones and reactive oxygen species. Autocatalysis arises from cross-activation between H2O2-catalyzed deprotection pro-benzoquinone arylboronic ester probe benzoquinone-catalyzed H2O2 production through cyling with ascorbate in an aerated buffered solution.
Christer Aakeröy opened a general discussion of the paper by Paul Beer: Does selectivity towards an anion change as function water content in your system? Beer answered: Although we have not undertaken such investigation with these host systems, I would predict t
Gefroren: Die spontane Kristallisation einer achiralen Verbindung in chiraler Konformation wird als Chiralitätsursprung absoluten asymmetrischen Synthese tertiärer Aminosäuren genutzt. dynamische axiale Chiralität aromatischer Amide im Kristall (siehe Bild) eingefroren und führt zur stereoselektiven Deprotonierung/Alkylierung Schema). α-Aminosäuren werden so mit bis zu 96% ee synthetisiert. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such...
Abstract The alkylation of 4‐substituted tetrazolo‐pyridines bearing electron‐withdrawing groups 7a – f to give the expected tetrazolo‐pyridinium salts , Me or Et as a mixture two N3/N2 isomers in good quantitative yields toluene, has been investigated. nature alkyl group did not significantly affect chemical shifts ratio, which was approximately 9:1, except for 7d 1:1 ratio obtained. alkylated were shown react with cyclopentadiene and, some cases, 2,3‐dimethylbutadiene and isoprene, whereas...
Molecule based signal amplifications relying on an autocatalytic process may represent ideal strategy for the development of ultrasensitive analytical or bioanalytical assays, main reason being exponential nature amplification. However, to take full advantage such amplification rates, high stability starting co-reactants is required in order avoid any undesirable background Here, basis a simple kinetic model cross-catalysis including certain degree intrinsic instability co-reactants, we...
Alison Edwards opened a general discussion of the paper by Christer Aakeröy: In first crystal structure depicted, imidazole nitrogen which is not making supramolecular interaction looks to be an electrostatically favourable (if hydrogen bonded) adjacent ri
The strength of autocatalytic reactions lies in their ability to provide a powerful means molecular amplification, which can be very useful for improving the analytical performances multitude and bioanalytical methods. However, one major difficulties designing an efficient amplification system is requirement reactants that are both highly reactive chemically stable order avoid limitations imposed by undesirable background amplifications. In present work, we devised reaction network based on...
Abstract The development of a new type biohybrid catalyst active in ionic liquid/water mixtures is described.