A5074658126- Malaria Research and Control
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Child Nutrition and Water Access
- Global Maternal and Child Health
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Parasites and Host Interactions
- Child and Adolescent Health
- Mosquito-borne diseases and control
- Asthma and respiratory diseases
- Hepatitis Viruses Studies and Epidemiology
- Neonatal Respiratory Health Research
- Blood groups and transfusion
- Pediatric health and respiratory diseases
- Travel-related health issues
- Ear Surgery and Otitis Media
- Hepatitis B Virus Studies
- Complement system in diseases
- Breastfeeding Practices and Influences
- Poverty, Education, and Child Welfare
- Air Quality and Health Impacts
- Smoking Behavior and Cessation
- Neonatal Health and Biochemistry
- Pneumonia and Respiratory Infections
Liverpool School of Tropical Medicine
2013-2023
University of Amsterdam
2009-2021
University of Liverpool
2009-2021
University of Manchester
2018
Manchester Academic Health Science Centre
2018
Emma Kinderziekenhuis
2005-2015
Academic Medical Center
1999-2012
Boston Children's Hospital
2006-2012
Liverpool Community Health NHS Trust
2007-2012
Tufts University
2011
Summary objectives To examine in pregnant women the relationship between HIV infection and malaria prevalence to determine, relation infection, effectiveness of sulphadoxine‐pyrimethamine clearing P. falciparum infection. method Descriptive cross‐sectional analysis at first antenatal visit delivery who had received two treatments for malaria. status was assessed 621 attended care rural hospitals southern Malawi 1993–94. Information collected on maternal age, parity gestational age....
<h3>AIM</h3> To determine the influence of placental malaria, maternal HIV infection, and hypergammaglobulinaemia on transplacental IgG antibody transfer. <h3>METHODS</h3> One hundred eighty materno-neonatal pairs from a Malawian population were assessed. Cord serum samples tested for total titres using nephelometry, specific to<i>Streptococcus pneumoniae</i>, measles, tetanus toxoid antibodies an enzyme linked immunsorbent assay (ELISA). <h3>RESULTS</h3> Multiple regression analyses showed...
The prevalence of infection with malarial parasites and the incidence anaemia delivery infants low birthweight (LBW) were investigated in 575 Malawian mothers who received one, two or three doses sulfadoxine-pyrimethamine (SP) during pregnancy. All subjects enrolled at their first antenatal visit all delivered hospital. Plasmodium falciparum was 35.3% primigravidae 13.6% multigravidae (P < 0.001). Mean haemoglobin concentration significantly lower than (8.8 v. 9.5 g/dl; P Of 233 women tested...
AbstractThe prevalence of anaemia during pregnancy was investigated in relation to parasite and spleen rates pregnant women living a defined study area rural Madang, Papua New Guinea. The effects anaemia, iron deficiency malaria on the foetus were investigated. There is high this population, with 44% primigravidae 29% multigravidae having severe [haemoglobin (Hb) <8 g dl−1] after 28 weeks gestation. odds ratio for at 0–16 gestation compared non-pregnant 4·7 (P<0·0001). Forty-seven per cent...
Summary The proportion of blood meals taken on humans which are infectious to mosquitoes in the Madang area, Papua New Guinea was estimated by two methods. In first, laboratory reared Anopheles farauti were fed individuals all ages at village surveys. results showed that 3·8% people and mean percentage became infected feeding these 37·9%. From average infected, probability a mosquito human would pick up infection 0·013±0·005. second approach identified Plasmodium falciparum, P. vivax...
Due to the potential risk of iron supplementation in replete children, it is important properly identify children who may require supplementation. However, assessment status has proven be difficult, especially living areas with high infection pressure (including malaria).Biochemical markers were compared bone marrow findings 381 Malawian severe anaemia.Soluble transferrin receptor/log ferritin (TfR-F index), using a cut-off 5.6, best predicted stores deficiency (sensitivity 74%, specificity...
Iron deficiency is highly prevalent in pre-school children developing countries and an important health problem sub-Saharan Africa. A debate exists on the possible protective effect of iron against malaria other infections; yet consensus lacking due to limited data. Recent studies have focused risks supplementation but individual's status risk remains unclear. Studies areas with a high burden infections often are exposed bias. The aim this study was assess predictive value baseline for...
BACKGROUND--A study was carried out to analyse the impact of maternal asthma on risk preterm delivery and contribution development childhood asthma. METHODS--Two cross sectional community studies 1872 children (5-11 years) in 1991 3746 1993 were performed. A respiratory health questionnaire distributed throughout 15 schools Merseyside completed by parents children. RESULTS--Asthmatic mothers more likely have a than non-asthmatic (odds ratio (OR) 1.49; 95% CI 1.10 2.02). Smoking separate...