- Musculoskeletal pain and rehabilitation
- Botulinum Toxin and Related Neurological Disorders
- Pain Management and Placebo Effect
- Pain Mechanisms and Treatments
- Pediatric Pain Management Techniques
- Clinical practice guidelines implementation
- Anesthesia and Pain Management
- Medical History and Innovations
- Spine and Intervertebral Disc Pathology
- Cardiac pacing and defibrillation studies
- Anesthesia and Sedative Agents
- Shoulder Injury and Treatment
- Trigeminal Neuralgia and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Opioid Use
- Hip disorders and treatments
- Nerve Injury and Rehabilitation
- Pain Management and Treatment
- Global Health and Surgery
- Respiratory and Cough-Related Research
- Cardiovascular Syncope and Autonomic Disorders
- Scoliosis diagnosis and treatment
- Dietetics, Nutrition, and Education
- Neurological diseases and metabolism
- Travel-related health issues
Médecins Sans Frontières
2016
University Medical Center Groningen
2006-2015
University of Groningen
2002-2015
Pain Management Institute
2006-2011
Dialyse Centrum Groningen
2002
Leiden University
1985
In the last decade, illness perceptions have been identified as important in treatment of fibromyalgia (FM). The aim present study was to examine and use revised Illness Perception Questionnaire patients with FM (IPQ-R-FM) their relationship quality life catastrophizing.A domain specific causal attributions related added IPQ-R-FM. psychometric properties IPQ-R-FM dimensions attribution scales were examined. domain, which describe most perceived causes for FM, analyzed. To analyze...
In patients who experience unilateral chronic pain, abnormal sensory perception at the non-painful side has been reported. Contralateral changes in these have given little attention, possibly because they are regarded as clinically irrelevant. Still, bilateral could become relevant if challenge correct identification of their dysfunction terms hyperalgesia and allodynia. Therefore, we used standardized quantitative testing (QST) protocol German Research Network on Neuropathic Pain (DFNS) to...
Objective. The aim of this study was to calculate the incidence and prevalence radiating low back pain, explore long-term clinical course pain including influence radiculopathy (in a subsample population) non-radiating thereon, describe general practitioners' (GPs') treatment strategies for pain. Design. A historic prospective cohort study. Setting. Dutch practice. Subjects. Patients over 18 years age with first episode registered by ICPC code L86. Main outcome measures. Incidence...
The African continent has the greatest burden of surgical disability-adjusted life years, yet least is known about operative care here. This analysis describes patients admitted to 7 hospitals supported by Médécins Sans Frontières (MSF) over 3 years in conflict-affected countries-Eastern Democratic Republic Congo, Central Republic, and South Sudan.A standardized data collection tool was used for routine inpatient between 2011 2013 at MSF facilities. Surgical records 14,482 were analyzed...
Patients with chronic pain and severe disuse syndrome have physiological, psychological social adaptations. The duration severity of complaints, combined previously failed treatments, makes them unsuitable for treatment in primary care.A prospective waiting list controlled study.A total 32 patients at least one year were included an inpatient multidisciplinary cognitive behavioural treatment.Patients assessed before the period, clinical phase, after phase follow-ups 6 months year. visual...
When patients cannot indicate pain, physiological parameters may be useful. We tested whether heart rate variability (HRV) parameters, as reflection of sympathetic and vagal tone, can used to quantify pain intensity.Prospective study.A standardized heat stimulus was applied the forearm in 75 healthy volunteers during three study periods 2 minutes.Before after each application, intensity measured by a visual analog scale (VAS) inter beat interval (IBI) recorded. Standard deviation normal...
The aim of this study is to investigate whether quantitative sensory testing with Von Frey monofilaments (VFMs) can be used for the quantification allodynia in patients chronic neuropathic pain, and how pain threshold affected skin differs from healthy skin.Using VFMs, we aimed determine 22 suffering as a consequence unilateral syndrome. We performed according Method Limits protocol. patient's own contralateral side 5 control participants obtain reference values.On side, found 20 out that...
Allodynia is a common and disabling symptom in many patients with neuropathic pain. Whereas quantification of pain mostly depends on subjective reports, allodynia can also be measured objectively quantitative sensory testing. In this pilot study, we investigated the clinical relevance testing Von Frey monofilaments as consequence syndrome, by means correlating scores thresholds obtained testing.During 4-week trial, administered cannabis extract to 17 allodynia. We quantified severity before,...
Lumbosacral radicular syndrome (LRS) is a self-limiting, benign, painful and impairing condition caused by lumbar disc herniation inflammatory processes around the nerve root. Segmental epidural steroid injections (SESIs) are helpful to reduce pain on short-term basis. It unknown whether SESIs an effective addition usual treatment of LRS in general practice. In our study, we assessed effectiveness disability as care for acute practice.A pragmatic, single-blinded, randomized controlled trial...
In Brief Study Design. A pragmatic, randomized, controlled, single-blinded trial in Dutch general practice. Objective. Assessing the costs and cost-effectiveness of adding segmental epidural steroid injections to care as usual radiculopathy Summary Background Data. Lumbosacral radicular syndrome (radiculopathy) is a benign, generally self-limiting but painful condition caused by herniated lumbar intervertebral disc, which results an inflammatory process around nerve root. Segmental could...
The ‘complex neural pulse’TM (CNP) is a neuromodulation protocol employing weak pulsed electromagnetic fields (PEMF). A pioneering paper reported an analgesic effect in healthy humans after 30 minutes of CNP-stimulation using three nested whole head coils. We aimed to devise and validate stimulator with novel design entailing multitude small coils at known anatomical positions on cap, improve applicability. main hypothesis was that CNP delivery this device would also increase heat pain...
Due to the lack of a specific diagnostic tool for neuropathic pain, grading system categorize pain as ‘definite’, ‘probable’, ‘possible’ and ‘unlikely’ was proposed. Somatosensory abnormalities are common in it has been suggested that greater number would be present patients with ‘probable’ ‘definite’ grades. To test this hypothesis, we investigated presence somatosensory by means Quantitative Sensory Testing (QST) clinical diagnosis correlated sensory profiles different Of who were...
Midazolam, a new short-acting benzodiazepine with promising premedicant effects, was investigated in double-blind, randomized clinical trial 203 patients versus fentanyl/droperidol and placebo. Subjective side-effects, amnesia overall satisfaction were recorded. Midazolam caused the greatest decrease anxiety level, while causing more confusion somnolence than placebo, less fentanyl/droperidol. Half who received midazolam reported anterograde amnesia. No serious side-effects reported. Patient...
Summary The aim of this study was to evaluate the ability a preliminary intravenous diagnostic test classify chronic orofacial pain patients into different subgroups. Patients with conditions that could not be unambiguously diagnosed. A retrospective evaluation series conducted pharmacodiagnostic tests, consisting consecutive administration drugs. Visual analogue scale scores were retrieved from all patients, based on which they classified responder groups. In total, 46 profiles analysed. Of...