Soichiro Takahashi

ORCID: 0000-0001-6885-7607
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About
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Research Areas
  • Stock Market Forecasting Methods
  • Complex Systems and Time Series Analysis
  • Neural Networks and Applications
  • Fuzzy Logic and Control Systems
  • Market Dynamics and Volatility
  • Financial Risk and Volatility Modeling
  • Financial Markets and Investment Strategies
  • Lipoproteins and Cardiovascular Health
  • Color perception and design
  • Blockchain Technology Applications and Security
  • Cancer, Lipids, and Metabolism
  • Metaheuristic Optimization Algorithms Research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Banking stability, regulation, efficiency
  • Multisensory perception and integration
  • Peptidase Inhibition and Analysis
  • Handwritten Text Recognition Techniques
  • Cardiovascular Function and Risk Factors
  • Educational Tools and Methods
  • Fuzzy Systems and Optimization
  • Signaling Pathways in Disease
  • Subtitles and Audiovisual Media
  • Categorization, perception, and language
  • Data Stream Mining Techniques
  • Cardiac Imaging and Diagnostics

Georgia Canines for Independence
2016-2022

The University of Tokyo
2015-2019

University of Yamanashi
2013

Shionogi (Japan)
2013

Tokyo Metropolitan Institute of Medical Science
2013

St. Marianna University School of Medicine
1997-1998

Nagaoka Red Cross Hospital
1979-1990

Niigata University
1975-1978

Niigata College of Technology
1976-1978

10.1016/j.physa.2018.07.017 article EN Physica A Statistical Mechanics and its Applications 2018-07-20

Abstract Secretory phospholipase A2 (sPLA2) plays a critical role in the genesis of lung inflammation through proinflammatory eicosanoids. A previous vitro experiment showed possible cell surface receptor for sPLA2 (PLA2R) clearance extracellular sPLA2. PLA2R and groups IB X are expressed lung. This study examined pathogenic airway using PLA2R-deficient (PLA2R−/−) mice. Airway was induced by immunosensitization with OVA. Compared wild-type (PLA2R+/+) mice, PLA2R−/− mice had significantly...

10.4049/jimmunol.1300738 article EN The Journal of Immunology 2013-07-02

Recent evidence indicates that the biological effects of secretory phospholipase A2 (sPLA2) cannot be fully explained by its catalytic activity. A cell surface receptor for sPLA2 (PLA2 1 [PLA2R]) and high-affinity ligands (including sPLA2-IB, sPLA2-IIE, sPLA2-X) are expressed in infarcted myocardium.This study asked whether PLA2R might play a pathogenic role myocardial infarction (MI) using mice lacking (PLA2R(-/-)).MI was induced permanent ligation left coronary artery. PLA2R(-/-) exhibited...

10.1161/circresaha.114.302319 article EN Circulation Research 2013-12-05

Interleukin 1 (IL-1) mediates many cellular functions, but the signal transduction mechanisms of its actions are not clearly understood. Here, we have examined exact participation cAMP in IL-1-induced production precursors matrix metalloproteinase (MMPs) and their specific inhibitor, tissue inhibitor metalloproteinases (TIMP) human uterine cervical fibroblasts. IL-1 significantly augmented proMMP-1 (vertebrate procollagenase), proMMP-3 (prostromelysin), TIMP without detectable changes...

10.1016/s0021-9258(18)54867-5 article EN cc-by Journal of Biological Chemistry 1991-10-01

To examine the association between depressive symptoms and plasma amino acid related metaboli in older adults.A total of 152 adults aged ≥65 years, residing Niigata, Japan, were used for analysis. We evaluated using Geriatric Depression Scale-15, which has been validated community-dwelling individuals, a cut off score ≥5 to classify participants as having symptoms. high-performance liquid chromatography-electrospray ionization mass spectrometry measure concentrations acid-related...

10.1111/ggi.13585 article EN Geriatrics and gerontology international/Geriatrics & gerontology international 2018-12-18

Low-density lipoprotein cholesterol (LDL-C), the ratio of LDL-C to high-density (HDL-C; LDL-C/HDL-C), and non-HDL-C were evaluated determine their ability predict cardiovascular disease (CVD) risk with pravastatin treatment.We conducted a large-scale randomized primary prevention trial in Japan (MEGA Study), which we randomly allocated 7832 mild hypercholesterolemic patients diet alone (n= 3966) plus groups 3866) followed them for an average 5 years. We compared baseline levels CVD incidence...

10.5551/jat.9183 article EN cc-by-nc-sa Journal of Atherosclerosis and Thrombosis 2011-12-01

This paper proposes a framework of robust technical trading with fuzzy knowledge-based systems (KBSs).

10.2139/ssrn.2996303 article EN SSRN Electronic Journal 2017-01-01

One of the fundamental questions about grapheme-colour synaesthesia is how specific associations between graphemes and colours are formed. We addressed this question by focusing on determinants synaesthetic for Japanese Kanji characters (logographic characters) using a psycholinguistic approach. Study 1 explored influence meaning has representing abstract meanings examining antonym pairs (i.e. with opposed to each other) in synaesthetes. Results showed that semantic relations influenced...

10.1098/rstb.2018.0349 article EN Philosophical Transactions of the Royal Society B Biological Sciences 2019-10-21

This paper explores Bitcoin intraday technical trading based on artificial neural networks for the return prediction.

10.2139/ssrn.3128726 article EN SSRN Electronic Journal 2018-01-01

This paper proposes a new fuzzy logic (FL)-based expert system with particle filtering and anomaly detection to create high-performance investment portfolios. In particular, our FL selects portfolio fine risk-return profiles from number of candidates by integrating multilateral performance measures including Sharpe, Sortino Sterling ratios. The consist various mean-variance portfolios multiple time-series models estimated filter detectors. an out-of-sample numerical experiment dataset...

10.2139/ssrn.2919171 article EN SSRN Electronic Journal 2017-01-01

A study was conducted to ascertain the presence of peroxidized low-density lipoprotein (LDL) in plasma and determine chemical structure LDL so that mechanism by which vascular complications develop may be elucidated patients with familial hypercholesterolemia (FH). Family trees showing moderate grade thickness Achilles' tendon were confirmed all patients. Cholesteryl ester, triglycerides (TG), free fatty acid (FFA), cholesterol (FC), phospholipids normal stained on a thin-layer...

10.1159/000163920 article EN Pathobiology 1994-01-01
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