- Stock Market Forecasting Methods
- Complex Systems and Time Series Analysis
- Neural Networks and Applications
- Fuzzy Logic and Control Systems
- Market Dynamics and Volatility
- Financial Risk and Volatility Modeling
- Financial Markets and Investment Strategies
- Lipoproteins and Cardiovascular Health
- Color perception and design
- Blockchain Technology Applications and Security
- Cancer, Lipids, and Metabolism
- Metaheuristic Optimization Algorithms Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Banking stability, regulation, efficiency
- Multisensory perception and integration
- Peptidase Inhibition and Analysis
- Handwritten Text Recognition Techniques
- Cardiovascular Function and Risk Factors
- Educational Tools and Methods
- Fuzzy Systems and Optimization
- Signaling Pathways in Disease
- Subtitles and Audiovisual Media
- Categorization, perception, and language
- Data Stream Mining Techniques
- Cardiac Imaging and Diagnostics
Georgia Canines for Independence
2016-2022
The University of Tokyo
2015-2019
University of Yamanashi
2013
Shionogi (Japan)
2013
Tokyo Metropolitan Institute of Medical Science
2013
St. Marianna University School of Medicine
1997-1998
Nagaoka Red Cross Hospital
1979-1990
Niigata University
1975-1978
Niigata College of Technology
1976-1978
Abstract Secretory phospholipase A2 (sPLA2) plays a critical role in the genesis of lung inflammation through proinflammatory eicosanoids. A previous vitro experiment showed possible cell surface receptor for sPLA2 (PLA2R) clearance extracellular sPLA2. PLA2R and groups IB X are expressed lung. This study examined pathogenic airway using PLA2R-deficient (PLA2R−/−) mice. Airway was induced by immunosensitization with OVA. Compared wild-type (PLA2R+/+) mice, PLA2R−/− mice had significantly...
Recent evidence indicates that the biological effects of secretory phospholipase A2 (sPLA2) cannot be fully explained by its catalytic activity. A cell surface receptor for sPLA2 (PLA2 1 [PLA2R]) and high-affinity ligands (including sPLA2-IB, sPLA2-IIE, sPLA2-X) are expressed in infarcted myocardium.This study asked whether PLA2R might play a pathogenic role myocardial infarction (MI) using mice lacking (PLA2R(-/-)).MI was induced permanent ligation left coronary artery. PLA2R(-/-) exhibited...
Interleukin 1 (IL-1) mediates many cellular functions, but the signal transduction mechanisms of its actions are not clearly understood. Here, we have examined exact participation cAMP in IL-1-induced production precursors matrix metalloproteinase (MMPs) and their specific inhibitor, tissue inhibitor metalloproteinases (TIMP) human uterine cervical fibroblasts. IL-1 significantly augmented proMMP-1 (vertebrate procollagenase), proMMP-3 (prostromelysin), TIMP without detectable changes...
To examine the association between depressive symptoms and plasma amino acid related metaboli in older adults.A total of 152 adults aged ≥65 years, residing Niigata, Japan, were used for analysis. We evaluated using Geriatric Depression Scale-15, which has been validated community-dwelling individuals, a cut off score ≥5 to classify participants as having symptoms. high-performance liquid chromatography-electrospray ionization mass spectrometry measure concentrations acid-related...
Low-density lipoprotein cholesterol (LDL-C), the ratio of LDL-C to high-density (HDL-C; LDL-C/HDL-C), and non-HDL-C were evaluated determine their ability predict cardiovascular disease (CVD) risk with pravastatin treatment.We conducted a large-scale randomized primary prevention trial in Japan (MEGA Study), which we randomly allocated 7832 mild hypercholesterolemic patients diet alone (n= 3966) plus groups 3866) followed them for an average 5 years. We compared baseline levels CVD incidence...
This paper proposes a framework of robust technical trading with fuzzy knowledge-based systems (KBSs).
One of the fundamental questions about grapheme-colour synaesthesia is how specific associations between graphemes and colours are formed. We addressed this question by focusing on determinants synaesthetic for Japanese Kanji characters (logographic characters) using a psycholinguistic approach. Study 1 explored influence meaning has representing abstract meanings examining antonym pairs (i.e. with opposed to each other) in synaesthetes. Results showed that semantic relations influenced...
This paper explores Bitcoin intraday technical trading based on artificial neural networks for the return prediction.
This paper proposes a new fuzzy logic (FL)-based expert system with particle filtering and anomaly detection to create high-performance investment portfolios. In particular, our FL selects portfolio fine risk-return profiles from number of candidates by integrating multilateral performance measures including Sharpe, Sortino Sterling ratios. The consist various mean-variance portfolios multiple time-series models estimated filter detectors. an out-of-sample numerical experiment dataset...
A study was conducted to ascertain the presence of peroxidized low-density lipoprotein (LDL) in plasma and determine chemical structure LDL so that mechanism by which vascular complications develop may be elucidated patients with familial hypercholesterolemia (FH). Family trees showing moderate grade thickness Achilles' tendon were confirmed all patients. Cholesteryl ester, triglycerides (TG), free fatty acid (FFA), cholesterol (FC), phospholipids normal stained on a thin-layer...