Ali D. Yucel
A5048263007- Computational Drug Discovery Methods
- Protein Structure and Dynamics
- CRISPR and Genetic Engineering
- Pluripotent Stem Cells Research
- thermodynamics and calorimetric analyses
- SARS-CoV-2 and COVID-19 Research
- Epigenetics and DNA Methylation
- Vitamin C and Antioxidants Research
Koç University
2020-2024
The COVID-19 pandemic has resulted in 198 million reported infections and more than 4 deaths as of July 2021 (covid19.who.int). Research to identify effective therapies for includes: (1) designing a vaccine future protection; (2) de novo drug discovery; (3) identifying existing drugs repurpose them immediate treatments. To assist repurposing design, we determine two apo structures severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease at ambient temperature by serial...
Abstract The COVID19 pandemic has resulted in 25+ million reported infections and nearly 850.000 deaths. Research to identify effective therapies for includes: i) designing a vaccine as future protection; ii) structure-based drug design; iii) identifying existing drugs repurpose them immediate treatments. To assist repurposing design, we determined two apo structures of Severe Acute Respiratory Syndrome CoronaVirus-2 main protease at ambienttemperature by Serial Femtosecond X-ray...