A5101565738- Luminescence and Fluorescent Materials
- Nanoplatforms for cancer theranostics
- Nanocluster Synthesis and Applications
- Advanced Photocatalysis Techniques
- Epigenetics and DNA Methylation
- Carbon and Quantum Dots Applications
- Molecular Sensors and Ion Detection
- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- Protist diversity and phylogeny
- Mercury impact and mitigation studies
- Photochromic and Fluorescence Chemistry
- Advanced Fluorescence Microscopy Techniques
- Lipid Membrane Structure and Behavior
- Click Chemistry and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Radical Photochemical Reactions
- Pharmacological Effects and Toxicity Studies
- Quantum Dots Synthesis And Properties
- Mass Spectrometry Techniques and Applications
- Renal cell carcinoma treatment
- bioluminescence and chemiluminescence research
- Porphyrin and Phthalocyanine Chemistry
- Analytical chemistry methods development
- Analytical Methods in Pharmaceuticals
Xiangyang Central Hospital
2024
South China University of Technology
2015-2022
Ministry of Education of the People's Republic of China
2020
State Key Laboratory of Luminescent Materials and Devices
2016-2018
Wuhan Center for Disease Control and Prevention
2012-2016
Wuxi Institute of Technology
2015-2016
Centers for Disease Control and Prevention
2015
Amines play vital roles in agricultural, pharmaceutical, and food industries, but volatile amine vapors are serious threats to human health. Previously reported fluorescent sensors for vapor detection usually suffer from aggregation-caused quenching (ACQ) effect need be dispersed solution or matrix materials. Herein, based on the fluorogen of 2-(2-hydroxyphenyl)quinazolin-4(3H)-one (HPQ) with aggregation-induced emission (AIE) properties, we have developed a sensor HPQ-Ac light-up through...
Photoactivatable probes for lipid droplets (LDs)-specific live-cell imaging are powerful tools investigating their biological functions through precise spatial and temporal control.
An easily accessible aggregation-induced emission (AIE) probe is developed for LD-specific imaging and dynamic movement tracking with advantages of NIR two-photon excited red fast cell permeability.
Photoactivatable fluorescent probes are ideal tools for organelle study with a significant advantage of high spatiotemporal resolution.
Highly red luminescent GSH–Cu nanoclusters were synthesized and could be used as nanosensors for Cr(<sc>vi</sc>) ions temperature.
A photoactivatable strategy is proposed for precise cancer therapy based on photooxidative dehydrogenation reaction, which demonstrated with the natural dihydroalkaloids of DHCHE and DHSAN as an example.
The development of a sensitive and reliable method for the detection bioaccumulated heavy metal toxins is highly desirable biotoxicity evaluation. However, conventional evaluation based on luminescent bacteria suffers from only being able to detect overall toxicity without selectivity in light-off mode. Although various synthetic fluorescent probes have been developed selective ions, they usually suffer aggregation-caused quenching after local accumulation biological systems. To tackle these...
Highly red luminescent Ag<sub>2</sub>S nanoclusters were synthesized and they show higher sensitivity as nanosensors for copper(<sc>ii</sc>) ion temperature.
Cancer therapies usually suffer from poor targeting ability and serious side effects. Photoactivatable cancer therapy has the significant advantage of a high spatiotemporal resolution, but most photoactivatable prodrugs require decoration with stoichiometric photocleavable groups, which are only responsive to ultraviolet irradiation low reaction efficiency. To tackle these challenges, we herein propose photoactivation strategy biogenic riboflavin as photosensitizer promote in situ...
Abstract Functional carbon materials have aroused much attention owing to their applications in cellular imaging and sensing. In this paper, we use a hydrothermal approach prepare luminescent sodium citrate dots (CDs) using glutathione (GSH) as the surface capping reagent. The effects of feed ratio, reaction temperature time on behavior CDs are investigated. Subsequently, as‐prepared characterized by UV‐vis, photoluminescence, X‐ray photoelectron spectroscopy (XPS), Fourier transform...
One strong fluorescent Bodipy-containing derivative was synthesized and characterized using 1H NMR, electrospray ionization mass spectrometry elemental analysis. Its electrochemical photophysical properties were investigated. In addition, the Bodipy could be used as an on–off probe for detection of Fe3+ ions based on inner filter effect because absorption band ion overlaps excitation very well upon irradiation with UV light. Furthermore, Bodipy-based sensor has obvious advantages including...
Abstract : Low toxicity and fluorescent nanomaterials have many advantages in biological imaging. Herein, we report a simple protein‐directed synthesis of water‐soluble gold nanoclusters (NCs) using bovine serum albumin (BSA) as the stabilizing agent. The as‐prepared Au NCs show red fluorescence with maximum peak at about 630 nm (quantum yield 7.6 %) are characterized terms photoluminescence spectrum, excitation transmission electron microscopy, Fourier transform infrared spectroscopy...
Chemotherapeutics with systemic administration usually suffer from low treatment efficacy and off-target toxicity. In contrary, the photoactivatable cancer theranostics can achieve image-guided precise control of therapeutic dose location. However, conventional chemotherapeutics require decoration additional photo-responsive groups through tedious synthetic procedures, which lead to undesirable toxic byproducts seriously restrict their applications. Herein, we propose a new strategy for...
Chemotherapies for cancer treatment usually suffer from poor targeting ability and serious side-effects. To improve the efficiency reduce side effects, photoactivatable chemotherapy has been recently proposed precise with high spatiotemporal resolution. However, most prodrugs require decoration by stoichiometric photo-cleavable groups, which are only responsive to ultraviolet irradiation low reaction efficiency. tackle these challenges, we herein propose a bioorthogonal photo-catalytic...
Chemotherapies for cancer treatment usually suffer from poor targeting ability and serious side-effects. To improve the efficiency reduce side effects, photoactivatable chemotherapy has been recently proposed precise with high spatiotemporal resolution. However, most prodrugs require decoration by stoichiometric photo-cleavable groups, which are only responsive to ultraviolet irradiation low reaction efficiency. tackle these challenges, we herein propose a bioorthogonal photo-catalytic...
Chemotherapies for cancer treatment usually suffer from poor targeting ability and serious side-effects. To improve the efficiency reduce side effects, photoactivatable chemotherapy has been recently proposed precise with high spatiotemporal resolution. However, most prodrugs require decoration by stoichiometric photo-cleavable groups, which are only responsive to ultraviolet irradiation low reaction efficiency. tackle these challenges, we herein propose a bioorthogonal photo-catalytic...
Chemotherapies for cancer treatment usually suffer from poor targeting ability and serious side-effects. To improve the efficiency reduce side effects, photoactivatable chemotherapy has been recently proposed precise with high spatiotemporal resolution. However, most prodrugs require decoration by stoichiometric photo-cleavable groups, which are only responsive to ultraviolet irradiation low reaction efficiency. tackle these challenges, we herein propose a bioorthogonal photo-catalytic...
Chemotherapies for cancer treatment usually suffer from poor targeting ability and serious side-effects. To improve the efficiency reduce side effects, photoactivatable chemotherapy has been recently proposed precise with high spatiotemporal resolution. However, most prodrugs require decoration by stoichiometric photo-cleavable groups, which are only responsive to ultraviolet irradiation low reaction efficiency. tackle these challenges, we herein propose a bioorthogonal photo-catalytic...
Chemotherapies for cancer treatment usually suffer from poor targeting ability and serious side-effects. To improve the efficiency reduce side effects, photoactivatable chemotherapy has been recently proposed precise with high spatiotemporal resolution. However, most prodrugs require decoration by stoichiometric photo-cleavable groups, which are only responsive to ultraviolet irradiation low reaction efficiency. tackle these challenges, we herein propose a bioorthogonal photo-catalytic...