Jialei Xu

ORCID: 0000-0001-6919-0883
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About
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Research Areas
  • Neurological Disease Mechanisms and Treatments
  • Oral microbiology and periodontitis research
  • Cerebrovascular and genetic disorders
  • Maternal Mental Health During Pregnancy and Postpartum
  • Salivary Gland Disorders and Functions
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Dementia and Cognitive Impairment Research
  • Streptococcal Infections and Treatments
  • Anesthesia and Neurotoxicity Research
  • Birth, Development, and Health
  • Neurological Disorders and Treatments
  • Circular RNAs in diseases

Guangxi Medical University
2024

Liaocheng People's Hospital
2020-2022

Soochow University
2013

Vascular dementia (VaD) is a progressive neurodegenerative disease with cognitive decline caused by cerebrovascular factors. Despite the great progress made in past decade, VaD still lacks effective treatments and peripheral blood biomarkers. In this study, we tested level of neurofilament light chain (NfL) patients explored its relationship impairment.A total 176 study subjects including 80 normal controls (NC) 96 were included our study. Upon admission, collected clinical biochemical...

10.1155/2020/6612871 article EN Disease Markers 2020-11-01

Neuregulin 1 (NRG 1) is a member of the epidermal growth factor (EGF) family and believed to play an important role in neuroplasticity. However, relationship between NRG vascular dementia (VaD) poorly understood. The purpose this study explore correlation neuregulin VaD. Patients Methods. From October 2018 September 2020, 93 VaD patients 79 control populations who attended Liaocheng People's Hospital were included study. Baseline characteristics including age, gender, years education, HDL,...

10.1155/2020/6683747 article EN cc-by BioMed Research International 2020-11-12

Cerebral atherosclerosis (AS) leads to high risk of cerebrovascular events. This study aims evaluate the diagnostic performance serum microRNA-130a-3p (miR-130a-3p) in cerebral AS patients, and construct a logistic model for 2-year events on basis prognostic potential miR-130a-3p.Serum samples were collected from 74 patients 62 control individuals, miR-130a-3p expression was investigated using reverse transcription quantitative PCR. Risk factors related with assessed regression analysis,...

10.1186/s12883-022-02829-5 article EN cc-by BMC Neurology 2022-08-22
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