A5103198538- Hearing, Cochlea, Tinnitus, Genetics
- Ion Channels and Receptors
- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
- Hearing Loss and Rehabilitation
- Primate Behavior and Ecology
- Medicinal Plants and Neuroprotection
- Asthma and respiratory diseases
- Animal Vocal Communication and Behavior
- Animal Nutrition and Physiology
- Ruminant Nutrition and Digestive Physiology
- Neuroscience and Neuropharmacology Research
- Pediatric health and respiratory diseases
- Synthesis and biological activity
- Hemispheric Asymmetry in Neuroscience
- IL-33, ST2, and ILC Pathways
- Head and Neck Anomalies
- Ion channel regulation and function
- Biochemical Acid Research Studies
- Obstructive Sleep Apnea Research
- Innovative Teaching Methods
- Post-Communist Economic and Political Transition
- Intracranial Aneurysms: Treatment and Complications
- Service-Oriented Architecture and Web Services
- Endometriosis Research and Treatment
Jiangnan University
2012-2021
Soochow University
2008-2021
State Key Laboratory of Food Science and Technology
2012-2021
Shanghai Huali Microelectronics (China)
2021
Nantong University
2016
Tongji Hospital
2004-2012
Huazhong University of Science and Technology
2004-2012
Shandong Agricultural University
2006-2011
Soochow University
2010
Air Force Engineering University
2010
The exposures to extremely low frequency magnetic field (ELF-MF) in our environment have dramatically increased. Epidemiological studies suggest that there is a possible association between ELF-MF exposure and increased risks of cardiovascular disease, cancers neurodegenerative disorders. Animal show may interfere with the activity brain cells, generate behavioral cognitive disturbances, produce deficits attention, perception spatial learning. Although, many research efforts been focused on...
Abstract Nanoparticulate titanium dioxide (nano TiO 2 ) is extensively applied in biological tissue engineering materials, food additives, cosmetics, and sunscreens. Numerous studies to date have demonstrated that nano penetrates through the digestive system possibly blood circulation, leading accumulation ovary consequent reproductive toxicity. However, mechanisms underlying toxic effects of on female remain be established. In this study, mice were exposed different doses (1.25, 2.5, or 5...
High-fat diets (HFDs) have been found to influence central nervous system development and cause cognitive impairments in human epidemiologic studies, as well animal investigations. These adverse effects on learning memory induced by an HFD associated with impaired hippocampus, including hippocampal oxidative damage. Previously, we had that α-lipoic acid (α-LA) could ameliorate the stress non-neural organs (liver, jejunum, spleen) a 10-week (21.2% fat) food regimen mice. In this study,...
Research in mammalian hair cell regeneration is hampered by a lack of vivo model adult mouse inner ear injury. In the present study we investigated effects combination single dose aminoglycoside followed loop diuretic mice. The auditory brainstem response threshold shift, extent and defining characteristics cochlear lesion were assessed verified at different time points post-treatment. Our data indicated that this drug caused rapid extensive death outer cells (OHCs). OHC presented throughout...
Although Ca(V)1.3 channels are known to be essential for neuronal excitation and signal transduction in the auditory system, their expression patterns cochlea still not fully understood, particularly regions where non-sensory cells located. We performed immunohistochemistry, western blotting reverse transcription-polymerase chain reaction (RT-PCR) identify distribution of rat cochlea. Immunohistochemistry revealed that were localized outer hair (OHCs), inner (IHCs), limbus laminae spiralis,...
Abstract Introduction In adolescence, the brain is still maturing, and disorders in maturation may affect normal development of brain. Exposure to titanium dioxide nanoparticles (TiO 2 NPs) has various potential negative effects on central nervous system. Bergamot essential oil (BEO) been found be effective for neuroprotection. Methods The rats were injected intraperitoneally with TiO NPs (20 mg/kg) and/or BEO (200 mg/kg). endogenous antioxidant state inflammatory parameters estimated using...
Objective To study the effect of hydrogen sulfide (H2S) on acute cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) and explore its mechanism. Methods (1) A total 48 adult male SD rats were randomly allocated into a normal group, SAH low dose NaHS group high (n=12). Rat models induced by injecting autologous blood prechiasmatic cistern. Rats in later two groups given 0.7 mg/kg 2.8 NaHS, respectively, 0.5 h modeling. Neurological scale scores assessed 24 modeling; HE...