- Lipoproteins and Cardiovascular Health
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrest and Resuscitation
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Pharmaceutical Economics and Policy
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Diabetes, Cardiovascular Risks, and Lipoproteins
- HIV-related health complications and treatments
- Pharmaceutical Practices and Patient Outcomes
- Climate Change and Health Impacts
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Risk Factors
- Cardiac Valve Diseases and Treatments
- Health Promotion and Cardiovascular Prevention
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiac Health and Mental Health
- Medication Adherence and Compliance
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
University of North Carolina at Chapel Hill
2015-2024
University Medical Center Hamburg-Eppendorf
2023-2024
Universität Hamburg
2023-2024
University of North Carolina Health Care
1982-2024
Merck & Co., Inc., Rahway, NJ, USA (United States)
2007-2024
University of Cambridge
2024
Weatherford College
2023
Analysis Group (United States)
2023
East Carolina University
2017-2021
Rutgers, The State University of New Jersey
2017-2021
We investigated the cognitive and psychiatric outcome 6 months after bilateral subthalamic nucleus deep brain stimulation (DBS) for treatment of Parkinson's disease (PD) using a control group.23 patients who underwent DBS were compared with 28 medically treated PD at baseline neuropsychological measures. In addition to group outcomes, we report reliable change indices (RCI) dementia caseness analysis.Patients demonstrated significant decline in verbal memory (p<0.003), trends on oral...
The effect of cycle length on atrial vulnerability was studied in 14 patients manifesting reproducible repetitive firing during extra-stimulus (A2) testing. Repetitive defined as the occurrence two or more premature responses with return (A2-A3) 250 msec less and subsequent mean 300 less, following A2. zone could be terms its longest shortest A1-A2 coupling intervals. Each patient tested at a long (CL1) (mean 884 msec) short (CL2) 557 msec). CL1 sinus rhythm CL2, an paced rhythm. occurred...
Omega-3 fatty acids (fish oils) reduce fasting serum triglyceride levels and cardiovascular disease risk in individuals without HIV infection. Whether omega-3 acid supplementation can hypertriglyceridemia associated with antiretroviral therapy is not known.We conducted an open-label, randomized trial that enrolled 52 patients receiving > or =3 active antiretrovirals who had of >200 mg/dL were to receive nutritionist-administered dietary exercise counseling fish oil for 16 weeks.Patients...
Abstract Background Global coronary heart disease (CHD) risk assessment is recommended to guide primary preventive pharmacotherapy. However, little known about physicians' understanding and use of global CHD assessment. Our objective was examine US awareness, use, attitudes regarding in clinical practice, how these vary by provider specialty. Methods Using a web-based survey family physicians, general internists, cardiologists, we examined awareness tools available calculate risk, method...
Premature ventricular complexes (PVCs) on a 2-minute electrocardiogram are common, largely asymptomatic finding associated with increased risk of coronary heart disease and death. They may reflect atherosclerosis or other pathogenic pathways that predispose to arrhythmias stroke.We conducted prospective evaluation the Atherosclerosis Risk In Communities Study cohort (n=14,783) middle-aged men women assess whether presence PVCs at study baseline (1987 1989) influenced incident stroke through...
Efficacious strategies for the primary prevention of coronary heart disease (CHD) are underused, and, when used, have low adherence. Existing efforts to improve use and adherence these efficacious been so intensive that they impractical clinical practice. We conducted a randomized trial CHD intervention (including computerized decision aid automated tailored messages) at one university general internal medicine After obtaining informed consent collecting baseline data, we patients (men women...