Abstract This study presents an assessment of scintillation observations obtained from PlanetiQ and Spire Global commercial CubeSat constellation radio occultation (RO) missions. A conservative algorithm is developed to detect distinguish ionospheric other scintillation‐like features in the RO measurements. Identified events are compared with independent instruments including ground‐based Navigation Satellite System monitors Constellation Observing for Meteorology, Ionosphere, Climate‐2...

CLN3 disease is a prevalent form of Neuronal Ceroid Lipofuscinosis (NCL) caused by inherited mutations in the gene, with symptoms such as vision loss, language impairment, and cognitive decline. The early onset visual deficits complicates neurological assessment brain pathophysiology underlying decline, while small number mutation cases humans hinders study sex differences. Building on our recent progress assessing auditory neurophysiological changes patients, we developed parallel approach...

Abstract Objective While immune checkpoint inhibitors are increasingly used for various cancers, unpredictable immune‐related adverse events (irAEs) such as autoimmune encephalitis is life‐threatening. Here, we report an association between human leukocyte antigen (HLA) and atezolizumab‐induced encephalitis. Methods From institutional prospective cohort encephalitis, identified patients with after the use of atezolizumab, a PD‐L1 (programmed death‐ligand 1) inhibitor, from August 2016 to...

Abstract Responding to the ever-growing demand for environmental information, National Oceanic and Atmospheric Administration (NOAA) seeks enter into contracts purchase Global Navigation Satellite System (GNSS) radio occultation (RO) observations produced by commercial vendors at a low-cost. GeoOptics is one vendor awarded contract with NOAA. operates Community Initiative Cellular Earth Remote Observation (CICERO) constellation of low-earth-orbiting (LEO) 6U CubeSats. The 6U-sized CICERO...

Abstract Deep signal fading due to ionospheric scintillation severely impacts global navigation satellite system (GNSS)‐based applications. GNSS receivers run the risk of loss under deep fading, which directly leads a significant decrease in availability. The impact on GNSS‐based applications can be mitigated via dual‐frequency signals provide backup channel. However, benefit diversity highly depends correlation processes between at different frequencies. This paper proposes Markov...

Abstract Plasma density depletions at midlatitudes during geomagnetic storms are often understood in terms of equatorial plasma bubbles (EPBs) due to their morphological similarity. However, our study reports the observations that reveal generation by local sources. During storm on 26 August 2018, Defense Meteorological Satellite Program and Swarm satellites detected Asian sector absence EPBs region. This observation total electron content (TEC) maps over Japan demonstrate traveling...

Abstract The development of an intense total electron content (TEC) depletion band over the United States during 8 September 2017 geomagnetic storm was understood as extension equatorial plasma bubble (EPB) to midlatitudes in previous studies. However, this study reports non‐EPB aspects within phenomenon. First, simultaneous emergence TEC at and EPBs region indicates that midlatitude is not initiated by EPB. Second, intensification decay intermediate latitudes anomalous. Third, location...

Deep signal fading due to ionospheric scintillation may cause loss-of-lock on one or more satellites in GNSS receiver tracking loops, which can degrade the navigation availability of GNSS-based aviation applications. Scintillation impact be mitigated via frequency diversity, decreases chance satellite loss presence deep and frequent fades. This study presents an improved process model that generates correlated processes dual-frequency signals simulates resulting evaluate benefit utilizing...

This paper presents a radial basis function (RBF) support vector machine (SVM)-based learning (ML) model to detect and classify disturbances observed in dual-frequency carrier phase measurements obtained by side-looking antennas on low Earth orbiting (LEO) CubeSats. The is designed distinguish radio frequency interference, satellite oscillator anomaly, ionospheric disturbances. trained ML applied collected Spire Global CubeSats 2021. testing validation results show that the RBF SVM achieved...

<h3>Abstract</h3> Extensive ionospheric studies were conducted to support the initial phase of system design approval for existing SLS-4000 GBAS installed at Antonio Carlos Jobim International Airport (formerly Galeão Airport) (GIG) in Rio de Janeiro, Brazil. This paper focuses on determining broadcast value standard deviation vertical gradients (or 𝜎_vig) that is required bound spatial Brazil under nominal conditions during daytime hours. The time-step method useful gaining...

Abstract Objective Lamotrigine is one of the most widely used antiepileptic drugs, but it has a critical issue skin rash if starting dose too high or escalation rate rapid. We investigated efficacy and safety novel rapid titration protocol for lamotrigine that takes only 11 days to reach daily 200 mg. Methods prospectively enrolled 33 adult patients (age 18‐85) who were diagnosed with epilepsy started administration first time at single tertiary hospital. Our new starts subthreshold drug...

Abstract Associations between human leukocyte antigen ( HLA ) and postural orthostatic tachycardia syndrome POTS have not been investigated. We included patients diagnosed with showing heart rate increases ≥ 50 during vital sign measurement or experiencing syncope/near‐syncope while standing (prominent ; n = 17). DQB 1*06:09 was present in seven (41%) patients, a significantly higher percentage than healthy Koreans (7%; odds ratio [ OR ] 8.7, 95% confidence interval CI 3.1–24.3, corrected P...

In this paper, we proposed a probabilistic localization of service robot using laser scanner and indoor GPS system. This scheme is sample based algorithm as an application Monte Carlo localization. Samples are scattered by referring to odometry data position And those evaluated map-matching method sensor distance error matching We able get more robust results these processes, even though the floor condition deteriorated there many or huge obstacles it possible that remove errors which caused...

Extensive ionospheric studies were conducted to support the initial phase of system design approval (SDA) for existing SLS-4000 GBAS installed at Galeão Airport (GIG) in Rio de Janeiro, Brazil. This paper focuses on determining broadcast value standard deviation vertical gradients (or sigma_vig) that is required bound spatial Brazilian region under nominal conditions during daytime hours. The days analysis selected by a combination high levels or nighttime scintillation and/or severe values...

Abstract Large amplitude plasma density irregularities have occasionally been detected at night in the midlatitude F region during geomagnetic storms. They are often interpreted terms of equatorial bubbles (EPBs) because morphology EPBs. This study assesses whether can be a determining factor ascribing origin such ionospheric irregularities. We address this question by analyzing observations First Republic China satellite (ROCSAT‐1) and Defense Meteorological Satellite Program (DMSP)‐F14...

The Total Electron Content (TEC) derived from Global Positioning System (GPS) radio occultation (RO) measurements contains residual bending errors that arise signal refraction and dispersion in the ionosphere. Motivated by need to ensure accuracy of TEC retrievals, particularly under high solar activity conditions, we investigate impact ionospheric on conventional dual-frequency TEC. This work marks a new attempt assessing error estimates using real RO measurements, contrast prior research...

Reliable Position Estimation Method of the Mobile Robot by Laser Scanner and Indoor GPS System Hyeyeon Chang, JongSuk Choi, Munsang Kim Pages 505-510 (2006 Proceedings 23rd ISARC, Tokyo, Japan, ISBN 9784990271718, ISSN 2413-5844) Abstract: The robust position estimation has been important issue mobile robot research for past few years. However, because physical constraint each sensor, sensor fusion algorithm arise alternative proposal solving problem. In this paper, we proposed a...

In recently years, various localization methods using two or more sensors have been proposed. Though it is still difficult to cope with the situation that sensor data are polluted. this paper, we proposed a probabilistic of service robot laser scanner and indoor GPS system for treating polluted situations. This scheme sample based algorithm as an application Monte Carlo localization. prediction phase, number samples scattered by referring odometry position system. And those evaluated...

Community Initiative for Cellular Earth Remote Observation (CICERO) is a planned constellation of low-earth-orbiting 6U cubeSats performing GNSS radio occultation (RO) Earth's atmosphere and surface. The goal CICERO to provide the first high-quality commercial data from space at low costs while enhancing weather climate forecasting capabilities. Before are used reliable forecasting, assessment its performance necessary. This study shows by comparing it with that COSMIC I. analysis was...

The discrepancy between social and biological time, described as 'social jetlag',can be estimated by the difference in mid-sleep time during weekend weekdays. Social jetlag is known to increase risk of metabolic complications, heart disease other problems. Anemia associated with sleep related conditions such night duration quality. In this study, we aimed evaluate association jet lag anemia. We analyzed adult participants (age ≥19) seventh Korea national health nutrition examination survey...