A5068589756- Advanced Sensor and Energy Harvesting Materials
- Conducting polymers and applications
- Electrochemical sensors and biosensors
- Antimicrobial agents and applications
- Anatomy and Medical Technology
- Dental Research and COVID-19
- Tactile and Sensory Interactions
- Digital Imaging in Medicine
- Pelvic floor disorders treatments
- Pickering emulsions and particle stabilization
- Advanced Materials and Mechanics
- RNA Interference and Gene Delivery
- Ion-surface interactions and analysis
- Polymer Surface Interaction Studies
- Nanoparticles: synthesis and applications
- Bacterial biofilms and quorum sensing
- Soft Robotics and Applications
- Additive Manufacturing and 3D Printing Technologies
- Nosocomial Infections in ICU
- Electrospun Nanofibers in Biomedical Applications
- Dental materials and restorations
- 3D Printing in Biomedical Research
- Organic Electronics and Photovoltaics
- Urinary Tract Infections Management
- Lipid Membrane Structure and Behavior
Universitat Ramon Llull
2017-2024
Institut Químic de Sarrià
2017-2024
In view of the current increase and spread antimicrobial resistance (AMR), there is an urgent need to find new strategies combat it. This study had two aims. First, we synthesized highly monodispersed silver nanoparticles (AgNPs) approximately 17 nm, functionalized them with mercaptopoly(ethylene glycol) carboxylic acid (mPEG-COOH) amikacin (AK). Second, evaluated antibacterial activity this treatment (AgNPs_mPEG_AK) alone in combination hyperthermia against planktonic biofilm-growing...
pH sensing for healthcare applications requires sensors with mechanically stable materials of high sensitivity and reproducibility combined low-cost fabrication technologies. This work proposes a fully printed sensor based on specially formulated conducting polymer deposited microelectrode in flexible substrate. A formulation, which polyaniline (PANI) polypyrrole (PPy) integrated polyelectrolyte poly(sodium 4-styrenesulfonate) (PSS), was prepared to be by inkjet printing (IJP). The has good...
This article describes the development of silicone gel-based inks for direct ink writing (DIW) with tunable viscoelastic properties that mimic mechanical behavior a wide range soft tissues.
Bioanalytical methods, in particular electrochemical biosensors, are increasingly used different industrial sectors due to their simplicity, low cost, and fast response. However, be able reliably use this type of device, it is necessary undertake in-depth evaluation fundamental analytical parameters. In work, parameters an amperometric biosensor based on covalent immobilization glucose oxidase (GOx) were evaluated. GOx was immobilized using plasma-grafted pentafluorophenyl methacrylate...
Abstract Despite modern advancements in sterilization and medical practices, bacterial infections remain a significant concern the implantation of devices. There is currently an urgent need for long‐lasting high‐stable strategies to avoid adhesion bacteria wide range materials present Here, versatile methodology create anti‐biofouling coatings that prevent silicone‐based used healthcare reported. These consist bifunctional ethylene glycol dimethacrylate as anchor between zwitterionic polymer...
Catheter-associated urinary tract infections (CAUTIs) are the most common health care-associated due to rapid bacterial colonization+ and biofilm formation in catheters. This behavior has been extensively documented medical devices. However, there is a few literature works on CAUTI providing model that allows exhaustive study of environment. The development an effective would be helpful identify factors promote strategies avoid it. In this work, we have developed test device surfaces by...
The use of transdermal delivery for nucleic acid administration is an interesting approach to overcoming limitations systemic routes, such as first-pass effects, the painful needle injection, or their poor biodistribution. Thus, a microneedle-based patch could represent turning point delivery, thanks possibility self-administration actives in painless and easy procedure. However, design systems with higher degree precision release clear need that has not been fully resolved. Committed...
Abstract Strain sensors for wearable electronic devices have received attention due to their potential application in medicine physiological monitoring or as part of advanced prosthetics. However, low sensitivity values well complex fabrication procedures remain significant challenges limiting the applicability. This work presents a strain sensor based on separation silver microplates immobilized stretchable substrate. The deposition is achieved through exposition glucosamine‐functionalized...
Biofilm formation in medical devices represents one of the major problems for healthcare system, especially those that occur on implantable silicone-based devices. To provide a general solution to avoid biofilm first stages development, this work studied how nanostructured metallic silver coatings hinder bacteria-surface interaction by preventing bacteria adhesion. The three nanostructures ("Sharp blades", "Thick blades" and "Leaves") combined superhydrophobic behavior with physical...
The synthesis of 2,2′-bipyrroles substituted at positions 5,5′ with pyrrolyl, N-methyl-pyrrolyl and thienyl groups their application in the preparation conducting polymers is reported herein. these monomers consisted two synthetic steps from a functionalized 2,2′-bipyrrole: Bromination corresponding 2,2′-bipyrrole followed by Suzuki or Stille couplings. These display low oxidation potential compared to pyrrole because extended length conjugation pathway. resulting can be polymerized through...
In this paper, we report a one-step method to obtain conductive polypyrrole thin films on flexible substrates. To do this, substrates were modified through allylamine plasma grafting create high amount of reactive amine groups PDMS surface. These are used during particle synthesis as anchoring points immobilize the polymeric chains substrate polymerization. Surface morphology modified, tailoring polyelectrolyte in obtaining different shapes nanoparticles that conform film. Depending...
Creating customizable soft medical implants and devices tailored to patient-specific anatomy represents a significant challenge in healthcare, requiring 3D-printable materials with viscoelastic properties similar those of natural tissue, high adaptability, biocompatibility. Here, we develop family silicone organogel inks for 3D printing tunable biomaterials via direct ink writing (DIW). We have developed set formulations comprising photo-cross-linkable polymers, oil, fumed silica...
Biofilm formation in medical devices represents one of the major problems for healthcare system, especially those that occur on implantable silicone-based devices. To provide a general solution to avoid biofilm first stages development, this work studied how nanostructured metallic silver coatings hinder bacteria-surface interaction by preventing bacteria adhesion. The three nanostructures ('Sharp blades', 'Thick blades' and 'Leaves') combined superhydrophobic behavior with physical...
Stretchable Electronics In article number 2200717, Salvador Borrós and co-workers report the fabrication of a strain sensor based on silver microplates immobilized stretchable substrate. The sensors stand out for its high conductivity (105 S m−1), sensitivity (GF = 900 000) ability to measure very small deformations even in dynamic range (0.02% strain).
Anti-Biofouling Coatings In article number 2201152, Robert Texidó, Pol Cabanach, Abdon Pena-Francesch, and colleagues use a coating strategy combining dopamine zwitterionic polymers to prevent bacteria from adhering soft flexible materials commonly used in medical devices. The coatings exhibit superhydrophilic anti-biofouling properties, leading >99% reduction bacterial adhesion. This bacteriophobic is implemented commercial urinary catheter, reducing adhesion by 2 orders of magnitude,...