A5101946287- Regional Economic and Spatial Analysis
- Ocular Oncology and Treatments
- Hearing, Cochlea, Tinnitus, Genetics
- Economic Growth and Productivity
- Connexins and lens biology
- Nerve injury and regeneration
- Microtubule and mitosis dynamics
- Cancer-related molecular mechanisms research
- Global Trade and Competitiveness
- Efficiency Analysis Using DEA
- Wound Healing and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Congenital Ear and Nasal Anomalies
- Genomics and Phylogenetic Studies
- Vestibular and auditory disorders
- RNA regulation and disease
- Protist diversity and phylogeny
Shanghai East Hospital
2025
Shanghai Ninth People's Hospital
2017-2020
Shanghai Jiao Tong University
2007-2020
Shanghai Institute of Hematology
2019
Increasing evidence suggests that aberrant long non-coding RNAs (lncRNAs) are significantly correlated with the pathogenesis, development and metastasis of cancers. RHPN1 antisense RNA 1 (RHPN1-AS1) is a 2030-bp transcript originating from human chromosome 8q24. However, role RHPN1-AS1 in uveal melanoma (UM) remains to be clarified. In this study, we aimed elucidate molecular function UM. The levels UM cell lines were examined using quantitative real-time polymerase chain reaction (qRT-PCR)....
Despite significant progress in skin wound healing, it is still a challenge to construct multifunctional bioactive dressings based on highly aligned protein fiber coated hydrogel matrix for antifibrosis regeneration that indistinguishable native skin. In this study, "dual-wheel-driven" strategy adopted modify the surface of methacrylated gelatin (GelMA) with magnetic nanocomposites-protein assemblies (MPF) consisting photothermal responsive antibacteria superparamagnetic...
Abstract Background Recessive mutations in GJB2 is the most common cause of genetic hearing loss worldwide. The aim this study to determine spectrum and frequency variants Chinese Han deaf patients investigate underlying causative genes with mono-allelic mutations. Methods We analyzed mutation screening results 1852 probands apparently autosomal-recessive our laboratory. Targeted next-generation sequencing 139 known deafness-related were performed 44 Results Bi-allelic was identified 25.65%...
Hearing loss is the most common sensory deficit in humans. Identifying genetic cause and genotype-phenotype correlation of hearing sometimes challenging due to extensive clinical heterogeneity. In this study, we applied targeted next-generation sequencing (NGS) resolve etiology a Chinese Han family with multiple affected members. Targeted 415 deafness-related genes identified heterozygous c.481C>T (p.R161C) mutation SOX10 homozygous c.235delC (p.L79Cfs∗3) GJB2 as separate pathogenic...
Regional innovation system is a vital component of the national system, as well base development regional economy. At present, shortage human resources and financial main obstruction for improvement innovative capacity system. Meanwhile, structure both inputs outputs gradually becomes factor influencing allocation efficiency. Due to certain constrains macroeconomic factors, can not be met in short period. Consequently, strategy improvement, analyzed by view very heated topic, efforts firms...