A5058703438- Additive Manufacturing and 3D Printing Technologies
- 3D Printing in Biomedical Research
- Cellular and Composite Structures
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Surgical Sutures and Adhesives
- Hemostasis and retained surgical items
- Advanced Sensor and Energy Harvesting Materials
- Advanced Materials and Mechanics
- Wound Healing and Treatments
- Tissue Engineering and Regenerative Medicine
- Polymer Surface Interaction Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Smart Materials for Construction
- Additive Manufacturing Materials and Processes
- Textile materials and evaluations
- Mechanical Behavior of Composites
- Hydrogels: synthesis, properties, applications
- Nanoparticle-Based Drug Delivery
- Polymer composites and self-healing
- Pickering emulsions and particle stabilization
- Urological Disorders and Treatments
- biodegradable polymer synthesis and properties
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Mesenchymal stem cell research
Center for Special Minimally Invasive and Robotic Surgery
2020-2024
University of California, Los Angeles
2019-2024
Terasaki Foundation
2020-2024
California NanoSystems Institute
2019-2024
University of British Columbia
2016-2021
Okanagan University College
2016-2021
Shahid Rajaee Teacher Training University
2014-2019
Three-dimensional flexible porous conductors have significantly advanced wearable sensors and stretchable devices because of their specific high surface area. Dip coating polymers with graphene is a facile, low cost, scalable approach to integrate conductive layers the polymer substrate platforms; however, products often suffer from nanoparticle delamination overtime decay. Here, fabrication scheme based on accessible methods safe materials introduced surface-dope silicone nanoplatelets. The...
Next generation engineered tissue constructs with complex and ordered architectures aim to better mimic the native structures, largely due advances in three-dimensional (3D) bioprinting techniques. Extrusion has drawn tremendous attention its widespread availability, cost-effectiveness, simplicity, facile rapid processing. However, poor printing resolution low speed have limited fidelity clinical implementation. To circumvent downsides associated extrusion printing, microfluidic technologies...
Abstract Background Increasing antibiotic resistance continues to focus on research into the discovery of novel antimicrobial agents. Due its and wound healing-promoting activity, metal nanoparticles have attracted attention for dermatological applications. This study is designed investigate scope bactericidal potential zinc ferrite (ZnFe 2 O 4 NPs), mechanism anti-bacterial action along with cytocompatibility, hemocompatibility, healing properties. Results ZnFe NPs were synthesized via a...
Hydrogel patches with high toughness, stretchability, and adhesive properties are critical to healthcare applications including wound dressings wearable devices. Gelatin methacryloyl (GelMA) provides a highly biocompatible accessible hydrogel platform. However, low tissue adhesion poor mechanical of cross-linked GelMA (i.e., brittleness stretchability) have been major obstacles their application for sealing repair wounds. Here, we show that adding dopamine (DA) moieties in larger quantities...
Abstract This study presents a low‐cost, tunable, and stretchable sensor fabricated based on spandex (SpX) yarns coated with graphene nanoplatelets (GnP) through dip‐coating process. The SpX/GnP is wrapped into silicone rubber (SR) sheath to protect the conductive layer against harsh conditions, which allows for fabricating washable wearable sensors. Dip‐coating parameters are optimized obtain maximum GnP coating rate. covering tailored achieve high stretchability beyond sensing limit of...
The natural local porosity variation in the native tissue can be replicated by graded scaffolds. Scaffolds with radial distribution a solution to improve both mechanical and biological functions of biomimetic In present study, fluid permeability as quantitative indicator performance is studied numerically experimentally for different pore shapes patterns scaffolds designed on basis triply periodic minimal surfaces (TPMSs). Among uniform scaffolds, those P* (P surface) Y** (G showed highest...
Laser additive manufacturing has led to a paradigm shift in the design of next-generation customized porous implants aiming integrate better with surrounding bone. However, conflicting criteria have limited development fully functional implants; increasing porosity improves body fluid/cell-laden prepolymer permeability at expense compromising mechanical stability. Here, functionally gradient and scaffolds designed based on interconnected triply periodic minimal surfaces (TPMS) are...
Blood loss by hemorrhaging wounds accounts for over one-third of ∼5 million trauma fatalities worldwide every year. If not controlled in a timely manner, exsanguination can take lives within few minutes. Developing new biomaterials that are easy to use non-expert patients and promote rapid blood coagulation is an unmet medical need. Here, biocompatible, biodegradable microneedle arrays (MNAs) based on gelatin methacryloyl (GelMA) biomaterial hybridized with silicate nanoplatelets (SNs)...
Hemorrhage and bacterial infections are major hurdles in the management of life-threatening surgical wounds. Most bioadhesives for wound closure lack sufficient hemostatic antibacterial properties. Furthermore, they suffer from weak sealing efficacy, particularly stretchable organs, such as lung bladder. Accordingly, there is an unmet need mechanically robust sealants with simultaneous effects. Here, injectable, photocrosslinkable, hydrogel sealant based on gelatin methacryloyl (GelMA),...
Mussel-inspired catechol-functionalization of degradable natural biomaterials has garnered significant interest as an approach to achieve bioadhesion for sutureless wound closure. However, conjugation capacity in standard coupling reactions, such carbodiimide chemistry, is limited by low yield and lack abundant sites. Here, a simple oxidative polymerization step before catechol-carrying molecules (i.e., 3,4-dihydroxy-l-phenylalanine, l-DOPA) potential amplify catechol function gelatin...