A5055628094- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Extracellular vesicles in disease
- Vestibular and auditory disorders
- Polyomavirus and related diseases
- Venous Thromboembolism Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Atrial Fibrillation Management and Outcomes
- Neurological Disorders and Treatments
- Infectious Encephalopathies and Encephalitis
- Immune cells in cancer
- Autoimmune Neurological Disorders and Treatments
- Alcoholism and Thiamine Deficiency
- Trigeminal Neuralgia and Treatments
- Moyamoya disease diagnosis and treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Retinal Imaging and Analysis
- Prion Diseases and Protein Misfolding
- Central Venous Catheters and Hemodialysis
- Glycogen Storage Diseases and Myoclonus
- Cerebrospinal fluid and hydrocephalus
- Cooperative Communication and Network Coding
- Long-Term Effects of COVID-19
Hospital La Paz Institute for Health Research
2022-2025
Universidad Autónoma de Madrid
2020-2025
Hospital Universitario La Paz
2024
Hospital Universitario de La Princesa
2019-2021
University of Glasgow
1989
New technologies could play a role in post-stroke aphasia (PSA). Our aims were to develop digital tool; evaluate its acceptance and usability by patients caregivers; demonstrate effectiveness improving language skills with PSA, applying it from the acute phase. The study consisted of two phases: development an interventional before-and-after study. During first week admission, tool, VerbalizAPP®, was installed for use help family/caregivers. PSA evaluated summarised version Boston Diagnostic...
Introduction: Extracellular vesicles (EVs) participate in cell-to-cell paracrine signaling and can be biomarkers of the pathophysiological processes underlying disease. In intracerebral hemorrhage, study number molecular content circulating EVs may help elucidate biological mechanisms involved damage repair, contributing valuable information to identification new therapeutic targets. Methods: The objective this was describe protein blood-derived following an hemorrhage (ICH). For purpose,...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main clinical features include fever, cough, and dyspnea; however, in a recent series, diarrhea (19.2%), headache (13.1%), impaired consciousness (7.5%) were also frequent symptoms.1 Rare associations like Miller-Fisher syndrome2 or encephalitis3 have been recently reported. However, to date, there are few studies demonstrating the presence of SARS-CoV-2 CSF neurologic symptoms.3
Abstract Introduction A consensus on the management of anticoagulated patients in acute phase ischaemic stroke has not yet been established. We aimed to evaluate clinical outcomes such based continuation or discontinuation anticoagulation. Methods Retrospective study with and cardioembolic source receiving anticoagulant therapy is done. Patients were classified anticoagulation at admission. Clinical outcomes, haemorrhagic events assessed. Multivariate logistic regression analysis, propensity...
Circulating extracellular vesicles (EVs) are proposed to participate in enhancing pathways of recovery after stroke through paracrine signaling. To verify this hypothesis a proof-of-concept study, blood-derived allogenic EVs from rats and xenogenic humans who experienced spontaneous good an intracerebral hemorrhage (ICH) were administered intravenously at 24 h subcortical ICH. At 28 days, both treatments improved the motor function assessment scales score, showed greater fiber preservation...
Despite the availability of effective photocoagulation treatment, diabetic retinopathy remains main cause blindness in persons aged between 20 and 64 years. We have examined effectiveness referral chain for by auditing medical records a representative sample being 226 patients (35% attenders) referred to special clinic. Patients were classified as ‘late’ or ‘not late’ using an algorithm which accounted state at previous frequency eye examination. Forty‐four (19%) considered been late. These...
The aim of the current study was to determine clinical characteristics migraine with aura (MA) as well frequency and patterns perfusion-computed tomography (PCT) alterations, in a series patients MA mimicking acute ischemic stroke.MA is one most frequent stroke mimics, following seizures psychiatric disorders. Previous case reports short have reported abnormal PCT MA.We conducted retrospective cohort including all consecutive presenting focal neurological symptoms during complete multimodal...
Background Timely coordination between stroke team members is of relevance for code management. We explore the feasibility and potential utility a smartphone application clinical neuroimaging data sharing improving workflow metrics pathways, professionals’ opinions about its use. Methods performed an observational pilot study including activations at La Paz University Hospital in Madrid, from June 2019 to March 2020. Patients were classified according activation or not JOIN app by attending...
Abstract Background and purpose Stroke mimics (SMs) account for a significant number of patients attended as stroke code (SC) with an increasing over the years. Recent studies show perfusion computed tomography (PCT) alterations in some SMs, especially seizures. The objective our study was to evaluate clinical characteristics PCT SMs SC order identify potential predictors SMs. Methods A retrospective performed including all activations undergoing multimodal CT non‐enhanced (CT), angiography...
Poststroke hyperglycaemia is an independent risk factor for poorer outcomes in patients treated with mechanical thrombectomy (MT) and associated a lower probability of functional recovery higher mortality at 3 months. This study aims to evaluate the association between glucose levels during cerebral reperfusion MT months, measured by subcutaneous continuous monitoring (CGM) devices. prospective observational recruit 100 ischaemic stroke large anterior circulation vessel occlusion, whom...
Background The increasing availability of neuroimaging tests has led to a rise in the identification incidental unruptured intracranial aneurysms (UIAs). Their management is under debate, with no consensus on their follow-up strategy, which can cause anxiety patients. Our aim evaluate impact diagnosis and imaging daily activities quality life. Methods A multicenter cross-sectional study was carried out patients UIAs undergoing watchful waiting. Exclusion criteria were history stroke, renal...
Unknown cardioembolic sources are frequent causes of cryptogenic stroke. We analyzed the risk atrial fibrillation (AF) or high burden ectopic activity (HBEA) in patients with stroke, assessing function and 1-year outcomes.
Deficits affecting hand motor skills negatively impact the quality of life patients. The NeuroData Tracker platform has been developed for objective and precise evaluation deficits. We describe design development analyse technological feasibility usability in a relevant clinical setting.A software application was Unity (C#) to obtain kinematic data from movement tracking by portable device with two cameras three infrared sensors (leap motion®). Four exercises were implemented: (a) wrist...
May 7, 2019April 9, 2019Free AccessPredictors of TC-Perfusion alterations in Stroke-Mimics attended as stroke-code (P3.3-066)Alicia Gonzalez-Martinez, Santiago Trillo-Senin, Carmen Benavides-Bernaldo de Quiros, Laura Casado Fernandez, Ines Muro Garcia, Maria Toledo Heras, Ana Beatriz Gago Veiga, Antonio Barbosa Del Olmo, Rafael Manzanares Soler, and Jose Aurelio Vivancos MoraAuthors Info & AffiliationsApril 2019 issue92 (15_supplement)https://doi.org/10.1212/WNL.92.15_supplement.P3.3-066...