A5027287788- Blood transfusion and management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Anesthesia and Sedative Agents
- Blood donation and transfusion practices
- Sepsis Diagnosis and Treatment
- Thermal Regulation in Medicine
- Hemoglobin structure and function
- Hemoglobinopathies and Related Disorders
- Anesthesia and Neurotoxicity Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac and Coronary Surgery Techniques
- Marriage and Sexual Relationships
- Anesthesia and Pain Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Plant and Fungal Species Descriptions
- Plant Diversity and Evolution
- Respiratory Support and Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Trauma and Emergency Care Studies
- Erythropoietin and Anemia Treatment
- Airway Management and Intubation Techniques
- Hemostasis and retained surgical items
Université Libre de Bruxelles
2012-2024
KU Leuven
2023
Spaarne Ziekenhuis
2022
Spaarne Gasthuis
2022
Centre Hospitalier Universitaire Brugmann
2006-2021
Grand Charleroi Hospital
2000-2021
Arthur B. McDonald-Canadian Astroparticle Physics Research Institute
2019
Université Paris-Sud
2019
Bicêtre Hospital
2019
Victor (Japan)
2019
The authors studied in a double-blind placebo-controlled study the effects of oral preoperative administration 5 micrograms/kg clonidine upon alfentanil and droperidol requirements, hemodynamic lability, distribution values heart rate blood pressure, plasma noradrenaline levels, two groups ten normotensive patients undergoing infrarenal aortic surgery. amounts supplementing standardized continuous infusion, injected to maintain stability, were statistically identical between (P = 0.23)....
BackgroundSusceptibility to Covid-19 has been found be associated with the ABO blood group, O type individuals being at a lower risk. However, underlying mechanism not elucidated. Here, we aimed test hypothesis that patients might have levels of antibodies than non-infected as they could offer some degree protection.MethodsAfter showing viral spike protein harbors glycan epitopes when produced by cells expressing relevant glycosyltransferases, like upper respiratory tract epithelial cells,...
BackgroundThe efficacy and safety of opioid-free anaesthesia during bariatric surgery remain debated, particularly when administering multimodal analgesia. As analgesia has become the standard care in many centres, we aimed to determine if such a strategy coupled with either dexmedetomidine (opioid-free anaesthesia) or remifentanil morphine transition (opioid-based anaesthesia), would reduce postoperative requirements opioid-related adverse events.MethodsIn this prospective double-blind...
The present study tested the hypothesis that anesthetic agents can alter tissue O2 extraction capabilities in a dog model of progressive hemorrhage. After administration pentobarbital sodium (25 mg/kg iv) and endotracheal intubation, dogs were paralyzed with pancuronium bromide, ventilated room air, splenectomized. A total 60 randomized 10 groups 6 each. first group served as control (C). second (P) received continuous infusion (4 mg.kg-2.h-2), which was started immediately after bolus dose....
The hemodynamic effects of dopamine and dobutamine (at doses 6 micrograms X kg-1 min-1) were compared during fluid resuscitation from septic shock induced by endotoxin (3 mg/kg) in the dog. In first part study, when a standard amount saline solution was infused (in 24 dogs), infusion resulted higher cardiac filling pressures than did infusion, whereas output. second titrated to maintain pulmonary artery balloon-occluded pressure at constant level total fluids significantly greater with used...
Abstract Introduction Six percent hydroxyethyl starch (HES) 130/0.4 is considered an alternative to human albumin (HA) and crystalloids for volume replacement in children undergoing cardiac surgery. In this large propensity-matched analysis, we aimed assess the efficacy safety of replacing HA with HES intraoperative therapy surgery cardiopulmonary bypass (CPB). Methods We retrospectively reviewed our database, including who underwent between January 2002 December 2010. Four was used until...
BACKGROUND Preoperative anaemia is associated with increased postoperative morbidity and mortality. Patient blood management (PBM) advocated to improve patient outcomes. OBJECTIVES NATA, the 'Network for advancement of management, haemostasis thrombosis', initiated a benchmark project aim providing basis educational strategies implement optimal PBM in participating centres. DESIGN Prospective, observational study online data collection 11 secondary tertiary care institutions interested...
This study was performed to test the hypothesis that tissue O2 extraction capabilities during hemorrhage may be greater when hematocrit (Hct) is initially reduced. Twenty-four anesthetized and splenectomized dogs were randomly assigned in three groups of eight each: group 1 (Hct 40), 40–45% Hct; 2 30), 30–35% 3 20), 20–25% Hct. In each animal, desired Hct obtained by normovolemic hemodilution using hydroxyethyl starch 450/0.7 maintained throughout experiment. delivery (DO2) progressively...
In paediatric cardiac surgery, red blood cell (RBC) transfusions are given to treat haemorrhage or increase oxygen delivery (therapeutic transfusion). Sometimes, RBCs added the prime solution avoid a too low haematocrit on bypass (CPB-driven Our study investigated whether reason for RBC transfusion might affect severe postoperative morbidity mortality. This retrospective cohort was conducted in tertiary care level, children's hospital. The charts of all patients admitted between 2006 and...
Fluid therapy during major hepatic resection aims at minimizing fluids the dissection phase to reduce central venous pressure, retrograde liver blood flow, and bleeding. This strategy, however, may lead hyperlactatemia. The Acumen assisted fluid management system uses novel decision support software, algorithm of which helps clinicians optimize therapy. study tested hypothesis that using this could decrease arterial lactate end when compared a more restrictive strategy.
Reduced cardiac output is a crucial determinant in hypovolemic, cardiogenic and obstructive types of acute circulatory failure, but considered less meaningful septic shock where the primary defect thought to be peripheral. In states, oxygen transport values are typically elevated, altered extraction (ratio uptake over supply) limits ability tissues increase their relation high needs. To correct tissue hypoxia, consumption should increased level equals demand lactic acidosis resolves. For...
In Brief Data on the effects of isovolemic hemodilution (IH) oxygenation during one-lung ventilation (OLV) are lacking. We studied 47 patients with hemoglobin >14 g/dL who were scheduled for lung surgery (17 normal function [group NL], 17 chronic obstructive pulmonary disease [COPD] COPD], and 13 COPD as control time/anesthesia CTRL]). Anesthesia was standardized. The tracheas intubated a double-lumen tube. Ventilatory settings fraction inspired oxygen remained constant. study performed in...