A5058242155- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Hemodynamic Monitoring and Therapy
- Cardiac and Coronary Surgery Techniques
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Pain Management
- Airway Management and Intubation Techniques
- Anesthesia and Neurotoxicity Research
- EEG and Brain-Computer Interfaces
- Blood transfusion and management
- Cardiac Arrest and Resuscitation
- Non-Invasive Vital Sign Monitoring
- Intraoperative Neuromonitoring and Anesthetic Effects
- Sepsis Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Veterinary Pharmacology and Anesthesia
- Blood Pressure and Hypertension Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Nausea and vomiting management
- Optical Imaging and Spectroscopy Techniques
- Cardiac Ischemia and Reperfusion
Centre Hospitalier Universitaire Brugmann
2003-2024
Université Libre de Bruxelles
2004-2024
KU Leuven
2023
Antwerp University Hospital
2023
Erasmus Hospital
2003-2023
Queen Fabiola Children's University Hospital
2021-2023
Cliniques Universitaires Saint-Luc
2023
Hôpital Bichat-Claude-Bernard
2022
Technical University of Munich
2022
Université Claude Bernard Lyon 1
2022
Perioperative bleeding is common in patients undergoing noncardiac surgery. Tranexamic acid an antifibrinolytic drug that may safely decrease such bleeding. We conducted a trial involving Patients were randomly assigned to receive tranexamic (1-g intravenous bolus) or placebo at the start and end of surgery (reported here) and, with use partial factorial design, hypotension-avoidance hypertension-avoidance strategy (not reported here). The primary efficacy outcome was life-threatening...
Recent data indicated a high incidence of inappropriate management neuromuscular block, with rate residual paralysis and relaxant-associated postoperative complications. These are alarming in that the available monitoring, as well myorelaxants their antagonists basically allow tolerated blockade. In this first European Society Anaesthesiology Intensive Care (ESAIC) guideline on peri-operative we aim to present aggregated evidence-based recommendations assist clinicians provide best medical...
Among patients having noncardiac surgery, perioperative hemodynamic abnormalities are associated with vascular complications. Uncertainty remains about what intraoperative blood pressure to target and how manage long-term antihypertensive medications perioperatively.To compare the effects of a hypotension-avoidance hypertension-avoidance strategy on major complications after surgery.Partial factorial randomized trial 2 management strategies (reported here) tranexamic acid versus placebo....
The present study tested the hypothesis that anesthetic agents can alter tissue O2 extraction capabilities in a dog model of progressive hemorrhage. After administration pentobarbital sodium (25 mg/kg iv) and endotracheal intubation, dogs were paralyzed with pancuronium bromide, ventilated room air, splenectomized. A total 60 randomized 10 groups 6 each. first group served as control (C). second (P) received continuous infusion (4 mg.kg-2.h-2), which was started immediately after bolus dose....
BACKGROUND There is a controversy in the literature whether deep compared with moderate neuromuscular block (NMB) improves surgical conditions for laparoscopic surgery. OBJECTIVES The primary outcome measure was to examine switching from NMB surgery obese; secondary measures were changes intra-abdominal pressure, time required perform gastrojejunal anastomosis and peri-operative complications. DESIGN A single-centre, randomised controlled study. Each patient taken as their own control...
The effects of four commonly used anesthetic agents, halothane, isoflurane, alfentanil, and ketamine, on cardiovascular function oxygen balance were studied in a dog model septic shock. After initial pentobarbital administration, the dogs given Escherichia coli endotoxin (3 mg/kg) and, after 30 min, fluids to restore cardiac filling pressures baseline levels. This resulted low resistance shock all animals. Dogs then for 2 h either halothane (n = 9, 0.5 MAC), isoflurane or alfentanil 150...
Goal-directed fluid therapy (GDFT) based on dynamic indicators of responsiveness has been shown to decrease postoperative complications and hospital length stay (LOS) in patients undergoing major abdominal surgery. The usefulness this approach still needs be clarified low-to-moderate risk Both pulse-pressure variation (PPV) pleth variability index (PVI) can used guide GDFT strategies. objective prospective randomized controlled trial was determine if the use PVI guided GDFT, when compared...
Abstract Background For patients undergoing noncardiac surgery, bleeding and hypotension are frequent associated with increased mortality cardiovascular complications. Tranexamic acid (TXA) is an antifibrinolytic agent the potential to reduce surgical bleeding; however, there uncertainty about its efficacy safety in surgery. Although usual perioperative care commonly consistent a hypertension-avoidance strategy (i.e., most continue their antihypertensive medications throughout period...
Background Acceptance of a lower transfusion trigger in the perioperative period requires study effects anesthetic depth on tolerance to acute isovolemic anemia. Anesthetic agents with negative cardiovascular system may exert proportionately greater depressant cardiac output response than tissue oxygen demand, reducing Methods In first study, animals were anesthetized halothane (n = 14; 23.8 +/- 4.8 kg, mean SD). second ketamine 24.3 4.7 kg). each dogs randomly allocated receive either low...
Hundreds of millions general anesthesia are performed each year on patients all over the world. Among these patients, 0.1-0.2% victims Accidental Awareness during General Anesthesia (AAGA), i.e., an unexpected awakening a surgical procedure under anesthesia. Although anesthesiologists try to closely monitor using various techniques prevent this terrifying phenomenon, there is currently no efficient solution accurately detect its occurrence. We propose conception innovative passive...
Following up on the successful BeSARPP annual meeting sustainability in anesthesia held November 2022, Board Members of met to draft recommendations regarding use inhaled anesthetics, that would help anesthesiologists decrease professional environmental impact their daily practice operating room. This manuscript discusses rationale for these recommendations. The major premise was none should compromise patient safety or level care we provide our patients. For measures beyond those addressing...