- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Erythropoietin and Anemia Treatment
- EEG and Brain-Computer Interfaces
- Health Systems, Economic Evaluations, Quality of Life
- Psychological Treatments and Disorders
- Attention Deficit Hyperactivity Disorder
- Botulinum Toxin and Related Neurological Disorders
- Genetic Neurodegenerative Diseases
- Functional Brain Connectivity Studies
- Electrochemical sensors and biosensors
- Developmental and Educational Neuropsychology
- Neuroscience and Neural Engineering
- Antiplatelet Therapy and Cardiovascular Diseases
- Aging, Health, and Disability
- Literature, Magical Realism, García Márquez
- Health, Nursing, Elderly Care
- Motivation and Self-Concept in Sports
- Diet and metabolism studies
- Cinema History and Criticism
- Medical research and treatments
- Nursing care and research
- Balance, Gait, and Falls Prevention
- Creativity in Education and Neuroscience
- Neurological and metabolic disorders
International Center of Neurologic Restoration
2016-2024
Cuban Neuroscience Center
2022
Universidad de La Laguna
2006
Servicio Canario de la Salud
2006
Understanding how a person lives with chronic illness, such as Parkinson's disease (PD), is necessary to provide individualized care and professionals role in person-centered at clinical community levels paramount. The present study was aimed analyze the psychometric properties of Living Chronic Illness-PD Scale (EC-PC) wide Spanish-speaking population PD. International cross-sectional retest carried out 324 patients from four Latin American countries Spain. Feasibility, acceptability,...
Global evaluations of Parkinson's disease (PD) severity are available, but their concordance and accuracy have not been previously tested. The present international, cross-sectional study was aimed at determining the agreement level among four global scales for PD (Hoehn Yahr, HY; Clinical Impression Severity, CGIS; Severity Index, CISI-PD; Patient PGIS) identifying which them better correlates with itemized assessments. Assessments included additional evaluation movement impairment,...
Objective: To evaluate EEG-derived functional connectivity (FC) patterns associated with mild cognitive impairment (MCI) in Parkinson’s disease (PD). METHODS: A sample of 15 patients without (PD-WCI), MCI (PD-MCI), and 26 healthy subjects were studied. The EEG was performed the waking state eyes closed, for analysis it used synchronization likelihood (SL) graph theory (GT). RESULTS: PD-MCI showed decreased FC frequencies alpha, posterior regions, delta a generalized distribution. Patients,...
Affective disorders in Parkinson’s disease (PD) concern several components of emotion. However, research on subjective feeling PD is scarce and has produced overall varying results. Therefore, this study, we aimed to evaluate the emotional experience its relationship with autonomic symptoms other non-motor features patients. We used a battery film excerpts elicit Amusement, Anger, Disgust, Fear, Sadness, Tenderness, Neutral State, 28 patients 17 healthy controls. Self-report scores emotion...
We report on the quantitative electroencephalogram (qEEG) and cognitive effects of Neuroepo in Parkinson's disease (PD) from a double-blind safety trial (https://clinicaltrials.gov/, number NCT04110678). is new erythropoietin (EPO) formulation with low sialic acid content satisfactory results animal models tolerance healthy participants PD patients. In this study, 26 patients were assigned randomly to (
La cirugía funcional constituye una alternativa terapéutica para los pacientes con enfermedad de Parkinson (EP). Es conocido que tanto la subtalamotomía como palidotomía bilaterales provocan complicaciones neurológicas, por lo en las técnicas ablativas no resulta recomendable el abordaje bilateral del GPi EP y se sugiere tener precaución indicación bilateral. Nuestro grupo ha perfeccionado técnica quirúrgica ablación núcleo subtalámico buscando disminuir aparición discinesias inducidas...
We used EEG source analysis to identify which cortical areas were involved in the automatic and controlled processes of inhibitory control on a flanker task compared potential efficacy recombinant-human erythropoietin (rHuEPO) performance Parkinson’s Disease patients. The samples 18 medicated PD patients (nine them received rHuEPO addition their usual anti-PD medication through random allocation other nine regular only) 9 age education-matched healthy controls (HCs) who completed with...
Abstract We used EEG source analysis to identify which cortical areas were involved in the automatic and controlled processes of inhibitory control on a flanker task compared potential efficacy recombinant-human erythropoietin (rHuEPO) performance Parkinson’ s Disease patients. The samples 18 medicated PD patients (nine them received rHuEPO addition their usual anti-PD medication through random allocation other nine regular only) 9 age education-matched healthy controls (HCs) who completed...
This study analyzes the relevance of motivational achievement and locus control variables on creative thinking. The sample was comprised 180 men 260 women from general population, between 18 65 years old (M = 28.68; SO 10.38). AI/ members were assessed with figural verbal forms Torrance Test Creative Thinking (TTCT) Pelechano's questionnaires Motivation, Achievement Anxiety Locus Control. Although percentage variance explained low, regression analyses showed that most important in "men's...
Introducción: El uso meticuloso de la neuroimagen para planificar posición del blanco quirúrgico y trayectoria hacia este, puede evitar los factores riesgo relacionados con cirugía, por lo que optimizar identificación anatómica núcleo Globo Pálido interno (GPi) el Subtalámico (NST) permitiría realizar menor cantidad registros cerebrales profundos, disminuiría tiempo quirúrgico, así como complicaciones asociadas a cirugía.Métodos: Se realizó un estudio retrospectivo, descriptivo-correlacional...
To analyze the responsiveness and interpretability of Living with Chronic Illness Scale in patients Parkinson's disease (LW-CI-PD).Longitudinal, international study, a convenience sample 153 PD Spanish Latin-American assessed at baseline one year later. The LW-CI-PD other clinical measures were applied. For responsiveness, Wilcoxon-Mann-Whitney test differences, correlation change between rating scales, standard error difference, relative change, Cohen's effect size standardized response...
Abstract Background Cognitive impairment is a feature of Parkinson’s Disease (PD) from the early stages, but currently, no treatment for cognitive deficits in PD available. Erythropoietin (EPO) has been studied its potential neuroprotective properties neurologic disorders with beneficial action on cognition. Objective To evaluate if NeuroEPO, new formulation EPO low content sialic acid, improves function patients. Methods A double-blind, randomized, placebo-controlled physician lead trial...