A5079328620- CNS Lymphoma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Glioma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Bone and Joint Diseases
- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- Management of metastatic bone disease
- Immune cells in cancer
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
Austin Health
2025
St Vincent's Hospital
2020-2024
The University of Melbourne
1981-2021
The University of Texas MD Anderson Cancer Center
2017
Not available.
Abstract Background Despite recent advances, optimal therapeutic approaches applicable to subpopulations with primary central nervous system (CNS) lymphoma outside of clinical trials remain be determined. Methods We performed a retrospective study immunocompetent, adult patients histologically confirmed diffuse large B‐cell the CNS (PCNSL). 190/204 (93%) (median age: 65) received one five high‐dose methotrexate (HD‐MTX) containing chemotherapy regimens: MPV/Ara‐C (HD‐MTX, procarbazine, and...
Primary CNS lymphoma (PCNSL) in immunocompetent patients is a disease of older adults who are often unsuitable for the high dose therapy or experience substantial morbidity from whole brain radiotherapy. As therapeutic studies limited, there need real world data to guide patient care. Here we report series 38 consecutive with PCNSL treated curative intent using R-MPV/Ara-C omission consolidative radiotherapy patients. Outcomes aged < 60 years and > were similar overall response rates 100% vs...