Donald H. Penning

ORCID: 0000-0001-7010-2430
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Anesthesia and Pain Management
  • Neonatal and fetal brain pathology
  • Anesthesia and Neurotoxicity Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Neuroscience and Neuropharmacology Research
  • Respiratory Support and Mechanisms
  • Pain Management and Opioid Use
  • Nausea and vomiting management
  • Neonatal Respiratory Health Research
  • Prenatal Substance Exposure Effects
  • Healthcare Operations and Scheduling Optimization
  • Cardiovascular Issues in Pregnancy
  • Airway Management and Intubation Techniques
  • Cardiac Arrest and Resuscitation
  • Hospital Admissions and Outcomes
  • Neuroscience of respiration and sleep
  • Birth, Development, and Health
  • Pregnancy-related medical research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Pregnancy and preeclampsia studies
  • Maternal and Perinatal Health Interventions
  • Anesthesia and Sedative Agents
  • Assisted Reproductive Technology and Twin Pregnancy
  • Maternal and fetal healthcare
  • Preterm Birth and Chorioamnionitis

Université Libre de Bruxelles
2024

Erasmus Hospital
2024

Henry Ford Health System
2017-2024

Michigan State University
2023

Henry Ford Hospital
2020-2022

UPMC Presbyterian
2022

University of Pittsburgh Medical Center
2022

MedStar Harbor Hospital
2022

Wayne State University
2022

Duke University Health System
2022

Some studies suggest that epidural analgesia prolongs labor and increases the incidence of cesarean section, especially if it is administered before 5 cm cervical dilation. The purpose current study was to determine whether early administration affects obstetric outcome in nulliparous women who are spontaneous labor.Informed consent obtained from 344 healthy with a singleton fetus vertex presentation, requested during at least 36 weeks' gestation. Each patient randomized receive either or...

10.1097/00000542-199406000-00006 article EN Anesthesiology 1994-06-01

Background This study looks at the validity of sequential organ failure assessment score (SOFA) in detecting mortality patients with Coronavirus disease 2019 (COVID-19) pneumonia. Also, it is looking to determine optimal SOFA that will discriminate between and survival. Methods It a retrospective chart review admitted Henry Ford Hospital from March 2020 December COVID-19 pneumonia who developed severe respiratory distress. We collected following information; patient demographics (age, sex,...

10.7759/cureus.26911 article EN Cureus 2022-07-16

Administrators routinely seek to increase contribution margin (revenue minus variable costs) better cover fixed costs, provide indigent care, and meet other community service responsibilities. Hospitals with high operating room (OR) utilizations can allocate OR time for elective surgery surgeons based partly on their margins per hour of time. This applies particularly when caseload is limited by nursing recruitment. From a hospital's annual accounting data cases, we calculated the following...

10.1097/00000539-200201000-00026 article EN Anesthesia & Analgesia 2002-01-01

Background Administrators at hospitals with a fixed annual budget may want to focus surgical services on priority areas ensure its community receives the best health possible. However, many lack detailed managerial accounting data needed that such change does not increase operating costs. The authors used hospital cost database investigate by how much in allocations of room (OR) time among surgeons can perioperative variable Methods obtained financial for all patients who underwent...

10.1097/00000542-200203000-00031 article EN Anesthesiology 2002-03-01

Administrators routinely seek to increase contribution margin (revenue minus variable costs) better cover fixed costs, provide indigent care, and meet other community service responsibilities. Hospitals with high operating room (OR) utilizations can allocate OR time for elective surgery surgeons based partly on their margins per hour of time. This applies particularly when caseload is limited by nursing recruitment. From a hospital's annual accounting data cases, we calculated the following...

10.1213/00000539-200201000-00026 article EN Anesthesia & Analgesia 2002-01-01

The intercristal line is known to most frequently cross the L4 spinous process or L4-5 interspace; however, it speculated be positioned higher during pregnancy because of exaggerated lumbar lordosis. Clinical estimation vertebral levels relying on use has been shown often inaccurate. We hypothesized that level determined by palpation would than ultrasound in pregnant women.Fifty-one term patients were recruited. Two experienced anesthesiologists performed estimates position palpation. Using...

10.1213/ane.0b013e318222abe4 article EN Anesthesia & Analgesia 2011-06-17

Implications In this preliminary investigation, we evaluated the safety and analgesic efficacy of IV remifentanil for labor pain. Four women were studied, then trial was terminated because administration novel synthetic opioid produced significant maternal side effects in absence effective pain control.

10.1213/00000539-200009000-00020 article EN Anesthesia & Analgesia 2000-09-01

Background The optimal timing of intubation for critically ill patients with severe respiratory illness remains controversial among healthcare providers. coronavirus disease 2019 (COVID-19) pandemic has raised even more questions about when to implement this life-saving therapy. While one group providers prefers early distress because these may deteriorate rapidly without it, other believe that should be delayed or avoided its associated risks including worse outcomes. Research question Our...

10.7759/cureus.19620 article EN Cureus 2021-11-16

Glioblastoma (GBM) is the most common and aggressive primary brain tumor. GBM contains a small subpopulation of glioma stem cells (GSCs) that are implicated in treatment resistance, tumor infiltration, recurrence, thereby considered important therapeutic targets. Recent clinical studies have suggested choice general anesthetic (GA), particularly propofol, during resection, affects subsequent response to treatments patient prognosis. In this study, we investigated molecular mechanisms...

10.3390/cells12151921 article EN cc-by Cells 2023-07-25

Background Laparoscopic pronuclear stage transfer (PROST) is the preferred method of embryo after in vitro fertilization many infertility programs. There are scant data to recommend use or avoidance any particular anesthetic agent for women undergoing this procedure. The authors hypothesized that propofol would be an ideal laparoscopic PROST because its characteristic favorable recovery profile includes minimal sedation and a low incidence postoperative nausea vomiting. purpose study was...

10.1097/00000542-199502000-00005 article EN Anesthesiology 1995-02-01

To examine the effects of a non-reactive carbon dioxide absorbent (AMSORB® Plus) versus traditional (Medisorb™) on FGF used by anesthesia providers and an electronic educational feedback intervention using Carestation™ Insights (GE HealthCare) provider-specific change in FGF.

10.1016/j.jclinane.2024.111441 article EN cc-by-nc-nd Journal of Clinical Anesthesia 2024-03-07

Introduction One of the most challenging scenarios an anesthesia provider can face is treating a can't intubate ventilate (CICV) patient. The incidence CICV estimated to be around one in 10,000 cases. According American Society Anesthesiology Closed Claims Study, adverse respiratory events are common type injury, with difficult intubation and ventilation contributing majority these objective this non-interventional quality improvement project was evaluate prior training, exposure,...

10.7759/cureus.23260 article EN Cureus 2022-03-17

At some surgical suites, if each nurse in the postanesthesia care unit (PACU) is caring for as many patients staffing standards permit (typically two), then remain their operating rooms (ORs) until PACU nurses become available to them. Surgical suite costs increase frequently OR resulting overtime finish day's scheduled cases. In this case study, we describe at a which on more than half of workdays least one patient waited an opening PACU. We applied statistical method previously developed...

10.1097/00000539-200104000-00029 article EN Anesthesia & Analgesia 2001-04-01
Coming Soon ...