A5049401870- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Radiomics and Machine Learning in Medical Imaging
- Clostridium difficile and Clostridium perfringens research
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
Shanghai Pudong New Area Gongli Hospital
2021-2023
Second Military Medical University
2021-2023
Shanghai Eighth People Hospital
2012
Wuhan No. 7 Hospital
2011
Objective We aimed to compare the cumulative efficacy and resistance of ADV monotherapy, add-on LAM (ADV + LAM), ETV ETV) combination therapy in LAM-resistant patients. Methods Ninety-one adult CHB patients with LAM-resistance mutations (YMDD) were identified. Of these 91, 29 treated 30 32 therapy, for at least 24 months. Results The mean serum HBV-DNA decreases from baseline 3, 6, 12, months -3.23, -4.41, -5.32, -5.58 log10IU/mL groups, respectively; most significant among three treatment...
Dear Editor, COVID-19 pandemic has brought an estimated 676 million cases and 6.88 deaths until March 2023. Multiple waves of outbreaks have been caused by SARS-CoV-2 its mutants, such as alpha, beta, gamma, delta, omicron. It remains a big challenge to limit the rapid spread mainly due our poor understanding pathological mechanisms. Upon infection, replicates in host cells, which does not standard rate or pattern. As such, incubation period viral load may vary between patients....
Abstract Background Corona Virus Disease 2019 (COVID-19) is currently a worldwide pandemic and has huge impact on public health socio-economic development. The purpose of this study to explore the diagnostic value quantitative computed tomography (CT) method by using different threshold segmentation techniques distinguish between patients with or without COVID-19 pneumonia. Methods A total 47 suspected were retrospectively analyzed, including nine positive real-time fluorescence reverse...
Hepatitis B virus (HBV) specifically infects hepatocytes, which can cause progressive liver fibrosis and a significantly increased risk of cancer. Multiple studies indicated host genetic, virological, immunological factors could affect the HBV infection. However, underlying mechanism involved in infection remained unclear. Based on analysis gene expression data 124 patients (GEO accession: GSE84044), molecular subgroups infected with hepatitis were identified this study, including C1, C2, C3...