A5081553552- Kawasaki Disease and Coronary Complications
- Sulfur Compounds in Biology
- Streptococcal Infections and Treatments
- Complement system in diseases
- Angiogenesis and VEGF in Cancer
- Plant tissue culture and regeneration
- Circular RNAs in diseases
- Mitochondrial Function and Pathology
- Outsourcing and Supply Chain Management
- Fibroblast Growth Factor Research
- MicroRNA in disease regulation
- PI3K/AKT/mTOR signaling in cancer
- Bioactive Compounds and Antitumor Agents
- Cancer, Hypoxia, and Metabolism
- Potato Plant Research
- GABA and Rice Research
- Biomedical Research and Pathophysiology
- Eicosanoids and Hypertension Pharmacology
- Corporate Governance and Law
- Polyamine Metabolism and Applications
- Cancer-related molecular mechanisms research
- Genetic Neurodegenerative Diseases
- Immunodeficiency and Autoimmune Disorders
- Autoimmune and Inflammatory Disorders Research
- Corporate Governance and Management
Al-Azhar University
2021-2023
Al-Azhar University
2020
Goethe University Frankfurt
2017-2019
University Hospital Frankfurt
2017
In this study, a set of novel benzoxazole derivatives were designed, synthesised, and biologically evaluated as potential VEGFR-2 inhibitors. Five compounds (12d, 12f, 12i, 12l, 13a) displayed high growth inhibitory activities against HepG2 MCF-7 cell lines further investigated for their activities. The most potent anti-proliferative member 12 l (IC50 = 10.50 μM 15.21 MCF-7, respectively) had the promising activity 97.38 nM). A biological evaluation revealed that compound 12l could arrest...
Ficolin-3 is one of the innate immunity molecules that was thought to play a pivotal role in Streptococcus pyogenes autoimmunity and its complications; rheumatic fever (RF) heart disease (RHD). We aimed disclose if there an association between ficolin-3 (FCN3) gene polymorphisms (rs4494157 rs10794501) RF with or without RHD for first time Egyptian adolescents.Serum level significantly elevated patients suffering from comparison control. Regarding FCN3 (rs4494157) polymorphism, significant...
Abstract Objective: Ficolin-3 is one of the innate immunity molecules that was thought to play a pivotal role in Streptococcus pyogenes autoimmunity and its complications; rheumatic fever (RF) heart disease (RHD). We aimed disclose if there an association between ficolin-3 ( FCN3) gene polymorphisms (rs4494157 rs10794501) RF with or without RHD for first time Egyptian adolescents. Results: Serum level significantly elevated patients suffering from comparison control. Regarding FCN3...
Abstract Background: The innate immunity molecules against Streptococcus pyogenes infections include ficolin-3 that was thought to have a role in autoimmune diseases resulting from this infection such as rheumatic fever (RF) which goes on and leads its most serious sequel, heart disease (RHD). We aimed study disclose if there is an association between gene polymorphisms (rs4494157 rs10794501) RF with or without RHD for the first time Egyptian adolescents. Methods: This carried out 160...