Many adults are living longer with health conditions in the United States. Understanding disability-adjusted life years (DALYs) for such may help to inform healthcare providers and their patients, guide interventions, reduce costs, improve quality of life, increase longevity aging Americans. The purpose this study was determine burden 10 a nationally-representative sample aged 50 older Data from 1998–2014 waves Health Retirement Study were analyzed. At each wave, participants indicated if...

In Brief Fibromyalgia and opioid use disorder (OUD) are highly impactful chronic illnesses with substantially overlapping psychosocial, biological, clinical features. Little previous research has examined interactions between fibromyalgia OUD. Limiting such been the requirement of a examination to diagnose fibromyalgia. The 2011 American College Rheumatology Survey (ACR-FMS) is validated self-report instrument high sensitivity specificity for intended enable in settings where impractical....

Years of life lost (YLL) is an epidemiological estimate premature death which provides increased weight to mortality at younger ages. This study aims quantify the impact overdose in adolescents from 2016 2020 using YLL and document role illicitly manufactured fentanyl rising rates.Data were obtained Centers for Disease Control Prevention's Wide-Ranging Online Data Epidemiologic Research file years 2016-2020 investigate unintentional aged 10-19. Unintentional rates investigated by year,...

Background: Discovery of modifiable factors influencing subjective withdrawal experience might advance opioid use disorder (OUD) research and precision treatment. This study explores one factor – catastrophizing a negative cognitive emotional orientation toward characterized by excessive fear, worry or inability to divert attention from symptoms.

Abstract Background Buprenorphine is a highly effective medication for opioid use disorder that underused by health care professionals (HCPs). Medications (MOUD) misinformation may be an important barrier to buprenorphine access, but most implementation strategies have aimed reduce negative attitudes towards patients with (OUD) rather than specific use. In this study, we assessed the degree which HCPs endorsed related buprenorphine, and whether associated willingness provide OUD. Methods...

SummaryThe quantity of 1% saline consumed and the development salt hypertension in rats were comparably enhanced by addition either glucose or sucrose 5% concentration to drinking solution. Cardiac hypertrophy lesions equivalently increased. A curious, as yet unexplained finding, is that whereas kidney enlargement accompanied consumption sucrose-saline solution, such was not case with glucose-saline. Here weight did exceed controls, reno-vascular although present less pronounced than when...

Objective: To determine the association between spinal cord injury (SCI) etiology categories and mortality, examine sub-categories mortality.Design: Prospective cohort study.Setting: Model Systems Shriners Hospital SCI units.Participants: Data were analyzed from 42,627 cases in System Collaborative Survival Study Database 1973 to 2017. Those with etiologies categorized as vehicular, violent, sports, falls, pedestrian, medical included.Interventions: Not applicable.Outcome Measure: Time...

McGrath, RP, Kraemer, WJ, Vincent, BM, Hall, OT, and Peterson, MD. Muscle strength is protective against osteoporosis in an ethnically diverse sample of adults. J Strength Cond Res 31(9): 2586-2589, 2017-The odds developing may be affected by modifiable nonmodifiable factors such as muscle ethnicity. This study sought to (a) determine whether increased was associated with decreased (b) identify the differed Data from 2013 2014 National Health Nutrition Examination Survey were analyzed....

Black patients seeking addiction care experience poorer treatment access, retention, and outcomes when compared to White counterparts. may have elevated group-based medical mistrust, which has been associated with health increased experiences of racism across multiple healthcare contexts. The relationship between mistrust expectations for among individuals remains untested.

Heavy chronic alcohol use may produce pain amplification through neurochemical and neuroplastic changes at multiple levels of the nervous system. Similar are thought to underlie nociplastic pain. The American College Rheumatology Fibromyalgia Survey has been used as a surrogate for pain, including among individuals with disorder (AUD). However, studies linking pain-motivated drinking lacking. present study aimed determine if is associated in AUD. To achieve this aim, new scale-the...

Medications for opioid use disorder (MOUD) are the gold standard. However, significant barriers limit their in primary care setting, including limited knowledge of medications and stigmatizing attitudes. In this study, we assess levels among care-aligned professionals (PCPs) currently practice, whether MOUD is associated with stigma treatment

Intact control and DOCA-treated rats were allowed to drink distilled water, a 1% NaCl solution, or 5% sucrose solution. Fluid intake, blood pressure changes, organoleptic responses evaluated. Control drank more solution than saline water. Hormone treatment slightly increased water intake greatly augmented consumption, but invariably depressed that of even though considerable polydipsia remained in effect. Hypertension cardiorenal enlargement characterized all groups given DOCA. Both...

SummaryPolyvinyl alcohol of 3 different molecular weights, 37,000, 133,000 and 185,-000, was injected daily subcutaneously into rats on a high NaCl intake. The lowest weight material not demonstrated in any the tissues examined and, over period studied, produced only mild elevation blood pressure third animals which received it. High PVA infiltrated number organs tissues. Most prominently it affected renal glomeruli causing swelling multiplication endothelial epithelial cells often crescent...

The aim of the study was to quantify burden premature mortality because opioid overdose in Ohio, document role fentanyl poisoning contribution this evolving epidemic, examine geographic, demographic, and temporal patterns within measure effect on lifespan state.A serial cross-sectional analysis performed for all fatal poisonings (N = 12,782) state Ohio between January 1, 2010 December 31, 2016. calculated Years Life Lost (YLL). YLL were mapped with respect geographic cultural region. spread...

Abstract Despite evidence suggesting race and ethnicity are important factors in responses to environmental exposures, drug therapies, disease risk, few studies focus on the health needs of racially- ethnically-diverse aging adults. The objective this study was determine burden 10 conditions across for a nationally-representative sample Americans. Data from 1998 2014 waves Health Retirement Study, an ongoing longitudinal-panel study, were analyzed. Those aged over 50 years who identified as...

In Brief Accidental overdose is increasing among perinatal women in Ohio and now accounts for more than 40% of pregnancy-associated years life lost the state.

Emerging evidence suggests the composition of local illicit drug markets varies over time and availability relative lethality drugs may contribute to temporal trends in overdose mortality. Law enforcement seizures represent a unique opportunity sample makeup markets. Prior research has associated shifts types seized unintentional The present report builds on this work by demonstrating novel methodology, Street-Drug Lethality Index, which serve as low-lag predictor deaths.

Central sensitization (CS) involves dysfunctional central nervous system pain modulation resulting in heightened perception. is not commonly assessed among patients with opioid use disorder (OUD), despite the fact that has been implicated development, maintenance, and relapse of OUD chronic may produce opioid-induced hyperalgesia. a plausibly important mechanism underlying complex relationship between pain. However, this premise largely untested.Participants (n = 141) were recruited from an...