A5088001978- Advancements in Transdermal Drug Delivery
- Food composition and properties
- Advanced Drug Delivery Systems
- Microencapsulation and Drying Processes
- Polysaccharides Composition and Applications
- Nanoparticle-Based Drug Delivery
- Drug Solubulity and Delivery Systems
- Proteins in Food Systems
- Morinda citrifolia extract uses
- Analytical Methods in Pharmaceuticals
- Blood Pressure and Hypertension Studies
- Natural Antidiabetic Agents Studies
- Hormonal and reproductive studies
- Pharmaceutical Quality and Counterfeiting
- Bee Products Chemical Analysis
- Bioactive Compounds and Antitumor Agents
- Pharmaceutical Practices and Patient Outcomes
- Nanoparticles: synthesis and applications
- Pharmacological Effects of Natural Compounds
- Medical Case Reports and Studies
- Glycosylation and Glycoproteins Research
- Diverse Scientific Research Studies
- Phytochemicals and Medicinal Plants
- Vagus Nerve Stimulation Research
- Nigella sativa pharmacological applications
University of Malaya
2012-2025
Sumatera Institute of Technology
2021
Sunway University
2016
Kagoshima University
2004
Abstract: The objective of this study was to compare the oil extraction yield and essential composition Indian Iranian Nigella sativa L. extracted by using Supercritical Fluid Extraction (SFE) solvent methods. In study, a gas chromatography equipped with mass spectrophotometer detector employed for qualitative analysis N. results indicated that main fatty acid identified in oils SFE were linoleic (22.4%–61.85%) oleic (1.64%–18.97%). Thymoquinone (0.72%–21.03%) found be major volatile...
Luteolin is a flavonoid compound that has been widely studied for its various anti-cancer properties and sensitization to multidrug-resistant cells. However, the limited solubility bioavailability of Lut hindered potential clinical use. Theoretically, combination this with vitamin E TPGS poloxamer 407 can produce synergistic effect enhance tumor apoptosis P-glycoprotein inhibition. This study aimed develop optimize TPGS/Poloxamer micelles loaded luteolin through investigating certain factors...
Fast melt tablets (FMTs) provide a convenient dosage form that rapidly dissolves on the tongue without need for water. Cocoa butter serves as suitable matrix system FMTs formulation, facilitating rapid disintegration at body temperature.
An excipient intended for direct compression in pharmaceutical tableting must show important features of flowability and compactibility. This study investigated pregelatinised sago starch as an tablets. Pregelatinised was prepared characterised. Its powder bulk properties performance the tablet formulations with paracetamol a model drug were compared against two commercial, directly compressible excipients, namely Avicel® PH 101 Spress® B820. The results showed that pregelatinisation did not...
Hard-shell capsules commonly consist of gelatin which is not a universal material considering it extracted from animal parts. Moreover, the mad cow disease triggered scrutinization use in pharmaceutical products. Hence, an alternative to conventional hard-shell needed. Carrageenan- (CRG-) based were successfully prepared by cross-linking CRG with maltodextrin (MD) and plasticizing sorbitol (SOR). These CRG-MD/SOR produced as oral drug delivery system (DDS). The physical properties...
This survey studied the different types of Complementary Alternative Medicine (CAM) usage, reasons CAM usage and out-of-pocket expenditure incurred by users with Type 2 diabetes. Methods: was a descriptive, cross-sectional that involved 132 diabetes patients. Results: A total 30.2% patients used dietary supplements, followed traditional Chinese medicine (TCM) (25.1%) Malay (17.9%). Two main for using include: need more control their also dissatisfaction conventional medicine. More than half...
<title>Abstract</title> Differential scanning calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FTIR), and High-Resolution Transmission Electron Microscopy (HRTEM) are a crucial analytical tool in pharmaceutical technology, enabling the characterization of drug molecules excipients, facilitating optimization dosage design development. Causes testosterone peak absence DSC spectra niosome formulations were discussed evidenced using DSC, FTIR HRTEM. The niosomes fabricated 1% powder...
Carrageenan-based (CRG) hard capsules have a slower disintegration rate compared to that of gelatin capsules. Therefore, there is an urgent need optimize the performance this material using oligomerization process. The preparation was conducted by oligomerizing CRG, cross-linking it with maltodextrin (MD), and plasticizing sorbitol (SOR). Based on our research, we found capsule prepared code CRG(O)-MD/SOR had ash content 11.80% water 17.20 ± 1.20 %. No microbes or yeast were in capsule, only...
Background: Diabetic ketoacidosis (DKA) is increasing in patients with type 2 diabetes Asian countries. However, there little information regarding the frequency and characteristics of DKA for Malaysian population. Objective: To identify different clinical biochemical features between adult 1 diabetes. Methods: A cross-sectional, retrospective study was performed at University Malaya Medical Centre (UMMC) January 2000 December 2005. All (aged >18 years) type1 or were included this study....
Purpose: To determine the factors associated with severity of hypoglycemia in hospitalized type 2 diabetes mellitus patients a tertiary health facility Malaysia.Methods: This retrospective study involved 207 hospitalised T2DM hypoglycaemia episodes from January 2008 to December 2012 and was conducted University Malaya Medical Centre, Petaling Jaya, Malaysia. Patients were classified into groups, viz, those who had on admission during hospital stay. admitted due while stay other causes but...
Lawsonia inermis is one of the most significant plants used in traditional medicine. However, many details dermal toxicity L. remain unknown. The objective this study to evaluate vivo acute and sub-acute ethanolic extract leaves. In experiment, a total 20 rats were divided into four groups five rats. A 30 six for experiment. at single dose 2000 5000 mg/kg body weight did not produce treatment-related signs or mortality all tested during 14-day observation period. repeated 28-day study,...
A simple, rapid, and sensitive method of liquid chromatography-tandem mass spectrometry (LC/MS/MS) was developed validated for the determination vardenafil in rabbit plasma. simple protein precipitation with ice-cold acetonitrile used plasma extraction. The transitions m/z 489⟶151 390⟶169 were to measure tadalafil (internal standard), respectively, a total assay run time 6 min. limit detection 0.2 ng/mL. reproducible intra-assay interassay precision ranging 1.17%–9.17% 1.31%–5.86%,...