A5086100658- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Neuroscience and Neuropharmacology Research
- Obstructive Sleep Apnea Research
- Antibiotics Pharmacokinetics and Efficacy
- Respiratory and Cough-Related Research
- Intraoperative Neuromonitoring and Anesthetic Effects
- Voice and Speech Disorders
- Sleep and Wakefulness Research
- Neurofibromatosis and Schwannoma Cases
- Peripheral Nerve Disorders
- Nerve Injury and Rehabilitation
- Airway Management and Intubation Techniques
- Pharmaceutical studies and practices
- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
Hospital Universitario Doctor Peset
2009-2020
Hospital Clínico Universitario de Valladolid
2016
Summary Objective To analyze the effectiveness and tolerability of perampanel across different seizure types in routine clinical care patients with idiopathic generalized epilepsy ( IGE ). Methods This multicenter, retrospective, 1‐year observational study collected data from patient records at 21 specialist units Spain. All who were aged ≥12 years, prescribed before December 2016, had a confirmed diagnosis included. Results The population comprised 149 (60 juvenile myoclonic epilepsy, 51...
Abstract Objective To assess the effectiveness and tolerability of perampanel (PER) monotherapy in routine clinical practice for treatment focal onset generalized tonic‐clonic seizures (GTCS). Methods This multicenter, retrospective, observational study was conducted patients aged ≥12 years treated with PER as primary or converted to by progressive reduction background antiepileptic drugs. Outcomes included retention, responder, seizure‐free rate after 3, 6, 12 months throughout follow‐up....
Purpose Evaluate real-life experience with eslicarbazepine acetate (ESL) after first monotherapy failure in a large series of patients focal epilepsy. Method Multicentre, retrospective, 1-year, observational study older than 18 years, epilepsy, who had failed antiepileptic drug and received ESL. Data from clinical records were analysed at baseline, 3, 6 12 months to assess effectiveness tolerability. Results Eslicarbazepine was initiated 253 patients. The 1-year retention rate 92.9%, the...
Objective The aim of this study is to evaluate propofol and midazolam as sleep inducers in drug‐induced endoscopy, for the topographic diagnosis upper airway obstruction during sleep; compare one other well with natural polysomnography results. Method Prospective series 16 patients suspected obstructive apnea. Following physical examination conventional polysomnography, nasendoscopy along simultaneous was performed, obtaining apnea‐hypopnea index, lowest oxygen saturation, apnea durations,...
<h3>Purpose</h3> Real-life experience with eslicarbazepine acetate (ESL) after first monotherapy failure in a large series of patients partial epilepsy <h3>Method</h3> Multicenter, retrospective, 1 year, observational study. Inclusion criteria: 1) older than 18 years; 2) partial-onset seizures; 3) Failure for any reason (efficacy, tolerability, compliance). Time-points revision were at 3, 6 and 12 months. Main objectives to assess efficacy tolerability. <h3>Results</h3> A total 253...