Shubhangi Aggarwal

ORCID: 0000-0001-7115-2931
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About
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Sulfur-Based Synthesis Techniques
  • Text and Document Classification Technologies
  • Fatty Acid Research and Health
  • Advanced Text Analysis Techniques
  • Click Chemistry and Applications
  • Spam and Phishing Detection
  • Telecommunications and Broadcasting Technologies
  • Lipid metabolism and biosynthesis
  • Coccidia and coccidiosis research
  • Synthesis of Indole Derivatives
  • Diversity and Career in Medicine
  • Covalent Organic Framework Applications
  • Advanced Data and IoT Technologies
  • Eurasian Exchange Networks
  • Reproductive tract infections research
  • Metal-Organic Frameworks: Synthesis and Applications
  • Dental Education, Practice, Research
  • Cyclopropane Reaction Mechanisms
  • Multimedia Communication and Technology
  • Catalytic C–H Functionalization Methods
  • Reproductive Health and Contraception
  • Synthesis and Biological Evaluation
  • Eicosanoids and Hypertension Pharmacology

Graphic Era University
2024

University of Southern California
2021-2024

University of Delhi
2023

Shyam Shah Medical College
2019

Indian Institute of Science Education and Research Pune
2016

The advent of ultra-large libraries drug-like compounds has significantly broadened the possibilities in structure-based virtual screening, accelerating discovery and optimization high-quality lead chemotypes for diverse clinical targets. Compared to traditional high-throughput which is constrained approximately one million compounds, screening approach offers substantial advantages both cost time efficiency. By expanding chemical space with synthesized from easily accessible reproducible...

10.1021/acschembio.3c00602 article EN ACS Chemical Biology 2024-04-10

Developing metal–organic framework (MOF)‐based proton‐conducting electrolytes for fuel‐cell applications is an important target that has drawn a lot of attention. A key approach involves the selective replacement guest species within pores to enhance performance. The modular and crystalline nature MOF permits controlled introduction such characterization their compositions with high precision, task which very difficult achieve in amorphous polymers. Herein, we partially replaced protons...

10.1002/ejic.201600364 article EN European Journal of Inorganic Chemistry 2016-06-20

Trichomonas vaginalis causes the most common, nonviral sexually transmitted infection. Only metronidazole (Mz) and tinidazole are approved for treating trichomoniasis, yet resistance is a clinical problem. The gold(I) complex, auranofin, active against T. other protozoa but has significant human toxicity. In systematic structure–activity exploration, we show here that diversification of complexes, particularly as halides with simple C1–C3 trialkyl phosphines or bistrialkyl phosphine can...

10.1021/acs.jmedchem.0c01926 article EN Journal of Medicinal Chemistry 2021-05-11

The first total convergent synthesis of 4(S),5(S)-oxido-17(S)-hydroxy-6(E),8(E),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid (1) is described. reported led to confirmation the native epoxydocosahexaenoic as biosynthetic precursor lipid mediators resolvin D3 and D4. These potent enzymatic products docosahexaenoic (DHA) are important signaling molecules in resolution inflammation. A stereocontrolled chiral pool-based synthetic strategy was employed, with key features including epoxide...

10.1039/d2ra01537d article EN cc-by-nc RSC Advances 2022-01-01

In this technology driven era, effective communication is the backbone for success of any business. Post- Covid times, and engaging digital communications have become integral part our day to lives ranging from basic online learning education delivery complex remote health care management. This increasing demand has given rise introduction many tools support video conferencing solutions. Many these limitation that they require dedicated hardware resources installation software at client host...

10.1063/5.0199040 article EN AIP conference proceedings 2024-01-01

In this day and age, software is an indispensable part of our per diem endeavours, thereby keeping a check on exploitable vulnerabilities has become vital function firm. The motivation paper to have better understanding vulnerabilities, creating tool for the industry practitioners identify critical vulnerability that could be detrimental firm's assets. article, 1999 related Google Chrome was analysed understand behaviour vulnerabilities. identification trends patterns using topic modelling...

10.31449/inf.v47i6.3712 article EN Informatica 2023-06-08

We describe a cascade reaction that selectively incorporates oxygen into the carbon−carbon backbone of alkynes using air as source. The process starts by lithiating readily available, electron-deficient 1,2,3-triazoles, resulting in an amphoteric lithium ketenimine intermediate. This intermediate can react with both electrophiles and nucleophiles. Under conditions outlined this study, we generate azavinyl radicals, which are rare subset captodative radicals. When exposed to atmospheric...

10.1021/jacs.3c06068 article EN Journal of the American Chemical Society 2023-09-21

Background: Specialised female surgical clinics are the need of day and not addressed routinely in Surgical Department. The management problems patients requires multidisciplinary approach mainly general surgery, obstetrics gynaecology, medicine, paediatrics, dermatology psychiatry. aim objective was to introduce a new concept subspecialty super speciality diseases.Methods: Prospective educational interventional study. 18 out 60 sensitised interns were introduced oriented specialised clinic....

10.18203/2349-2902.isj20191893 article EN International Surgery Journal 2019-04-29
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