Marko Spasić

ORCID: 0000-0001-7144-1696
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Glioma Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Pancreatic and Hepatic Oncology Research
  • Meningioma and schwannoma management
  • Pancreatitis Pathology and Treatment
  • Neurofibromatosis and Schwannoma Cases
  • CAR-T cell therapy research
  • Cancer and Skin Lesions
  • Breast Lesions and Carcinomas
  • Gastrointestinal disorders and treatments
  • Immunotherapy and Immune Responses
  • Intraperitoneal and Appendiceal Malignancies
  • Cancer Genomics and Diagnostics
  • Hearing, Cochlea, Tinnitus, Genetics
  • Breast Cancer Treatment Studies
  • Vestibular and auditory disorders
  • Trauma Management and Diagnosis
  • Appendicitis Diagnosis and Management
  • Pleural and Pulmonary Diseases
  • Ear Surgery and Otitis Media
  • Esophageal and GI Pathology
  • Oral and Maxillofacial Pathology
  • Neuroendocrine Tumor Research Advances
  • Gastroesophageal reflux and treatments
  • Metastasis and carcinoma case studies

University of Kragujevac
2016-2025

Clinical Centre of Kragujevac
2016-2025

University Clinical Centre
2024

Parker Institute for Cancer Immunotherapy
2021-2023

University of California, San Francisco
2019

University of California, Los Angeles
2011-2017

Neurological Surgery
2011-2016

UCLA Health
2015

Ronald Reagan UCLA Medical Center
2015

UCLA Medical Center
2015

Chemotherapy combined with immunotherapy has improved the treatment of certain solid tumors, but effective regimens remain elusive for pancreatic ductal adenocarcinoma (PDAC). We conducted a randomized phase 2 trial evaluating efficacy nivolumab (nivo; anti-PD-1) and/or sotigalimab (sotiga; CD40 agonistic antibody) gemcitabine/nab-paclitaxel (chemotherapy) in patients first-line metastatic PDAC ( NCT03214250 ). In 105 analyzed efficacy, primary endpoint 1-year overall survival (OS) was met...

10.1038/s41591-022-01829-9 article EN cc-by Nature Medicine 2022-06-01

Changing daily habits such as diet, hygiene and physical activity may be some of the consequences COVID-19 pandemic. The aim study was to analyze effect this pandemic on lifestyle, activity, eating among students.This cross-sectional involved 171 students from Faculty Medical Sciences, University Kragujevac, Serbia. Data were statistically analyzed using Wilcoxon Signed-Rank test, Marginal homogeneity test Chi-square test. differences considered significant when p ≤ 0.05.In study, it...

10.3389/fpubh.2022.862816 article EN cc-by Frontiers in Public Health 2022-03-17

This study investigates the synthesis, characterization, and cytotoxicity of dinuclear palladium(II) complexes with glycine (Pd1), alanine (Pd2), methionine (Pd3) as ligands. UV-Vis fluorescence spectroscopy were used to investigate complexes’ interactions calf thymus DNA (CT-DNA) bovine serum albumin. The obtained measurements demonstrate that Pd1 Pd2 have stronger binding affinities for CT-DNA compared Pd3, Pd3 exhibiting most significant against MDA-MB-231 cancer cell line. behavior was...

10.3390/molecules30071534 article EN cc-by Molecules 2025-03-30

OBJECTIVE Superior semicircular canal dehiscence (SSCD) is a rare disorder characterized by the formation of third opening in inner ear between superior and middle cranial fossa. Aberrant communication through this causes syndrome hearing loss, pulsatile tinnitus, disequilibrium, autophony. This study analyzed clinical outcomes single-institution series patients with SSCD undergoing surgical repair same otolaryngologist neurosurgeon. METHODS All who underwent at University California, Los...

10.3171/2015.8.jns15391 article EN Journal of neurosurgery 2016-02-12

The objective of this study was to evaluate the characteristic symptoms and treatments for lateral semicircular canal dehiscence (LSCD) posterior (PSCD) its proposed mechanism. A acquired in any canals may evoke various auditory (autophony inner ear conductive hearing loss) or vestibular (vertigo, Tullio phenomenon, Hennebert sign) by creating a "third mobile window" bone that enables aberrant communication between nearby structures. PubMed search performed using keywords lateral, posterior,...

10.1055/s-0035-1551667 article EN Journal of Neurological Surgery Part B Skull Base 2015-05-29

Abstract BACKGROUND: Superior semicircular canal dehiscence (SSCD) presents with varying degrees of auditory and vestibular dysfunction. The condition is confirmed on high-resolution computed tomography (CT) imaging, symptoms are often improved by surgical repair. Although a classic middle fossa craniotomy has been used good results, recent advances in technique have allowed for modification the traditional approach into smaller skin incision minimally invasive keyhole craniectomy roughly...

10.1093/ons/opw046 article EN Operative Neurosurgery 2017-04-19
Coming Soon ...