Helen Shulver
- Radiopharmaceutical Chemistry and Applications
- Animal Virus Infections Studies
- Prostate Cancer Treatment and Research
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Bone health and treatments
- Viral gastroenteritis research and epidemiology
- Cardiac, Anesthesia and Surgical Outcomes
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- Sepsis Diagnosis and Treatment
Northern General Hospital
2024
University of Sheffield
2017-2023
Weston Park Cancer Centre
2017
Adjuvant therapies can prevent/delay bone metastasis development in breast cancer. We investigated whether serum turnover markers early disease have clinical utility identifying patients with a high risk of developing metastasis.Markers formation (N-terminal propeptide type-1 collagen [P1NP]) and resorption (C-telopeptide [CTX], pyridinoline cross-linked carboxy-terminal telopeptide [1-CTP]) were measured baseline (pretreatment blood samples from 872 large randomized trial adjuvant...
The protection of fourth dose mRNA vaccination against SARS-CoV-2 is relevant to current global policy decisions regarding ongoing booster roll-out. We aimed estimate the effect vaccination, prior infection, and duration PCR positivity in a highly-vaccinated largely prior-COVID-19 infected cohort UK healthcare workers.
Abstract Background Many hospitals introduced procalcitonin (PCT) testing to help diagnose bacterial coinfection in individuals with COVID-19, and guide antibiotic decision-making during the COVID-19 pandemic UK. Objectives Evaluating cost-effectiveness of using PCT decisions hospitalized as part a wider research programme. Methods Retrospective individual-level data on patients were collected from 11 NHS acute hospital Trusts Health Boards England Wales, which varied their use baseline...