A5100335723- Catalytic C–H Functionalization Methods
- Synthesis and Catalytic Reactions
- Catalytic Cross-Coupling Reactions
- Ionic liquids properties and applications
- Electrochemical Analysis and Applications
- Crystallization and Solubility Studies
- Metamaterials and Metasurfaces Applications
- Analytical chemistry methods development
- Quinazolinone synthesis and applications
- Click Chemistry and Applications
- Radical Photochemical Reactions
- Analytical Chemistry and Chromatography
- Nanomaterials for catalytic reactions
- Asymmetric Hydrogenation and Catalysis
- Sulfur-Based Synthesis Techniques
- X-ray Diffraction in Crystallography
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Soft Robotics and Applications
- Electrochemical sensors and biosensors
- Carbohydrate Chemistry and Synthesis
- Advanced Antenna and Metasurface Technologies
- Catalytic Alkyne Reactions
- Crystal structures of chemical compounds
- Conducting polymers and applications
First Affiliated Hospital of Henan University
2019-2025
Yingkou Institute of Technology
2021-2025
Hebei University of Science and Technology
2019-2025
Zhejiang University of Technology
2021-2024
China Pharmaceutical University
2024
State Key Laboratory of Natural Medicine
2024
Zhejiang Shuren University
2024
Soochow University
2014-2024
Zhejiang A & F University
2022-2024
Shandong First Medical University
2024
Abstract An easily synthesized and accessible N,O‐bidentate auxiliary has been developed for selective CH activation under palladium catalysis. The novel showed its first powerful application in functionalization of remote positions. Both C(sp 2 )H 3 bonds at δ‐ ε‐positions were effectively activated, thus giving tetrahydroquinolines, benzomorpholines, pyrrolidines, indolines moderate to excellent yields by palladium‐catalyzed intramolecular amination.
Summary Plants modify their development to adapt environment, protecting themselves from detrimental conditions such as chilling stress by triggering a variety of signaling pathways; however, little is known about how plants coordinate developmental patterns and responses at the molecular level. Here, we demonstrate that interacting transcription factors Os MADS 57 TB 1 directly target defense gene WRKY 94 organogenesis D14 trade off functions controlling/moderating rice tolerance cold....
α-amino acids bearing aromatic side chains are important synthetic units in the synthesis of peptides and natural products. Although various β-C-H arylation methodologies for amino acid derivatives involving assistance directing groups have been extensively developed, syntheses that directly employ N-protected as starting materials remain rare. Herein, we report an N-acetylglycine-enabled Pd-catalysed carboxylate-directed β-C(sp3)-H aliphatic acids. In this way, non-natural can be prepared...
In this paper, we describe the advances in design, actuation, modeling, and control field of continuum robots. After decades pioneering research, many innovative structural design actuation methods have arisen. Untethered magnetic robots are a good example; its external characteristic allows for miniaturization, they gotten lot interest from academics. Furthermore, with proprioceptive abilities also studied. modeling approaches based on mechanics geometric shaping hypothesis made significant...
Binary DESPs and ternary are used for the separation of target compounds as efficient adhesive materials.
A rhodamine-inspired fluorescence dye (2) bearing 7-diethylaminocoumarin fluorophore was designed as a platform for the construction of an NIR and ratiometric fluorescent probe. The ring-open form 2 shows absorption emission; however, its ring-closed displays visible emission because intact involved in structure, providing basis based on spirocyclization-induced switching mechanism. With platform, we developed novel probe R1, thiolactone 2, sensing Hg2+, environmentally biologically...
Abstract Graphene oxide (GO) has been developed as an inexpensive, environmental friendly, metal‐free carbocatalyst for the dehydrogenation of nitrogen heterocycles. Valuable compounds, such quinoline, 3,4‐dihydroisoquinoline, quinazoline, and indole derivatives, have successfully used substrates. The investigation various oxygen‐containing molecules with different conjugated systems indicated that both groups large π‐conjugated system in GO sheets are essential this reaction. magnified image
Reducing the lateral scale of two-dimensional (2D) materials to one-dimensional (1D) has attracted substantial research interest not only achieve competitive electronic applications but also for exploration fundamental physical properties. Controllable synthesis high-quality 1D nanoribbons (NRs) is thus highly desirable and essential further study. Here, we report implementation supervised machine learning (ML) chemical vapor deposition (CVD) quasi-1D few-layered WTe2 NRs. Feature importance...
Diabetic wounds severely influence life, facing grand challenges in clinical treatments. The demand for better treatment is growing dramatically. wound healing challenging because of inflammation, angiogenesis disruptions, and tissue remodeling. Based on sequencing results diabetic patients' skins artificial intelligence (AI)-assisted bioinformatics, we excavate a potential therapeutic agent Trichostatin A (TSA) target histone deacetylase 4 (HDAC4) healing. molecular docking simulation...
An Fe-catalyzed 2-deoxy glycosylation method was developed from 3,4-O-carbonate glycals directly at room temperature. This novel approach enabled facile access to alkyl and aryl glycosides in high yields with exclusive α-stereoselectivity, tolerating various alcohols, phenols, glycals. The synthetic utility advantage of this strategy have been demonstrated by the modification six natural products construction a tetrasaccharide.
A successful protocol has been developed for δ-arylation of β-arylethamines at the ortho position under mild conditions. The newly methodology first presents broad substrate scope, great functional group tolerance, and good to excellent yield in synthesis substituted β-arylethylamines. transformation represents a practical advantage oxalyl amide assistance with C–H functionalization remote position.
A palladium-catalyzed carboxylic acid-directed cross-coupling of an ortho-C(sp2) atom aromatic acids with aliphatic aziridines to construct the β-arylethylamine skeleton via C–H activation has been developed. The reaction proceeded under mild conditions great substrate scope. Meanwhile, in drugs or bioactive compounds could be easily generated a single step. catalytic amount cesium carbonate was crucial realizing selective synthesis.
Long-term agricultural management practices affect soil health, but identifying measurable properties that reflect health (soil indicators – SHIs) is a challenge. Five long-term (>40 years) crop rotations with varying cropping frequency, diversity, fertility and lime treatments were sampled as part of the Soil Heath Institute's North American Project to Evaluate Health Measurements (NAPESHM) at University Albert Breton Plots research site in 2019, additional samples collected 2020 for...
The composite of graphene oxide(GO) and chitosan(CS) effectively addresses the issues oxide aggregation, difficult recovery, poor mechanical properties small surface area chitosan, while significantly improving adsorption performance chitosan. However, during process, active sites chitosan may react, which reduces number available thereby impacts overall efficiency. In this study, a aerogel (GCG) was prepared using glutamine-modified oxide, its for methyl orange Cu 2+ investigated. results...
Abstract Using cardanol polyoxyethylene ether, maleic anhydride, and sodium bisulfite as main raw materials, a new type of surfactant, dicardanol sulfosuccinate anionic–nonionic surfactant was synthesized. The effects reaction temperature, material ratio, catalyst dosage on esterification were investigated by single factor orthogonal experiment method, the conditions sulfonation optimized. Fourier infrared spectroscopy, liquid chromatography‐mass spectrometry proton nuclear magnetic...
We present a visible-light-promoted radical cascade cyclization reaction via sulfonylmethylation, cyano insertion, and of unactivated alkenes bearing groups. This strategy enables the rapid synthesis sulfonylmethylated phenanthridines...
Palladium-catalyzed oxalyl amide directed ortho-alkynylation of arylalkylamine derivatives is reported for the first time. A wide variety β-arylethamine and γ-arylpropamine are compatible with this protocol. This method provides a general means to synthesize substituted alkynylarylalkylamine derivatives, highlighting ability in promoting C-H functionalization at unique δ ε positions.